A discussion of every disease caused by modification of the various apoptotic pathways would be impractical, but the concept overlying each one is the same: the normal functioning of the pathway has been disrupted in such a way as to impair the ability of the cell to undergo normal apoptosis.

Instead of the gradual transition through the capillaries from arteries to veins that is typical of normal functioning vasculature, AVMs cause direct associations of the arteries and veins.

Persons with bipolar disorder may have periods of normal or near normal functioning between episodes.

An infection that does not and will not produce clinically evident impairment of normal functioning, such as the presence of the normal bacteria and yeasts in the gut, is not considered a disease ; by contrast, an infection that is asymptomatic during its incubation period, but expected to produce symptoms later, is usually considered a disease.

During 1920-50, the leaders of the Communist Party and Soviet state considered repressions as a tool for securing the normal functioning of the state system as well as preserving and strengthening positions of their social base, presented by working class, in society.

The achievements of the democratic period, such as the establishment, strengthening or expansion of the various governmental and civil society structures and integrative processes necessary for normal functioning of the reunited state and nation, were too easily overlooked.

Bernheim argued that anyone could be hypnotised, that it is an extension of normal psychological functioning, and that its effects are due to suggestion.

There are a number of chemicals and genetic disorders which disrupt normal functioning of ion channels and have disastrous consequences for the organism.

Population-based studies ( e. g. Michael, et al., 2000 ) using the SF-36 have found significant decrease in QoL dimensions, including role / physical, bodily pain, vitality and social function, results that were supported by Rothrock's ( et al., 2002 ) cross-sectional study of IC patients showing decreased physical functioning, decreased ability to function in one's normal role, decreased vitality, and depression.

Anxiety or fear that interferes with normal functioning may be classified as an anxiety disorder.

Many web design tutorials also point out that client-side redirecting tends to interfere with the normal functioning of a Web browser's " back " button.

In chronic opioid users, such as those on Chronic Opioid Analgesic Therapy ( COAT ) for managing severe, chronic pain, behavioural testing has shown normal functioning on perception, cognition, coordination and behaviour in most cases.

:# The avoidance, anxious anticipation or distress in the feared situation ( s ) interferes significantly with the person's normal routine, occupational ( or academic ) functioning, or social activities or relationships, or there is marked distress about having the phobia.

:# The avoidance, anxious anticipation, or distress in the feared social or performance situation ( s ) interferes significantly with the person's normal routine, occupational ( academic ) functioning, or social activities or relationships, or there is marked distress about having the phobia.

Although psi-related experiences can occur in the context of such psychopathologies as psychotic, dissociative, and other disorders, most individuals who endorse a belief in psi generally have normal intellectual functioning and lack serious psychopathology.

Short-lived psychosis triggered by stress is known as brief reactive psychosis, and patients may spontaneously recover normal functioning within two weeks.

These are characterised by problems with mood control and the psychotic episodes appear associated with disturbances in mood, and patients will often have periods of normal functioning between psychotic episodes even without medication.

Epithelial cells ( which are non-circulating ) normally have active integrins at their cell membrane, helping maintain their stable adhesion to underlying stromal cells that provide signals to maintain normal functioning.

* Civil disorder – A form of collective violence interfering with the peace, security, and normal functioning of the community.

Ellert Nijenhuis and colleagues suggest a distinction between personalities responsible for day-to-day functioning ( associated with blunted physiological responses and reduced emotional reactivity, referred to as the " apparently normal part of the personality " or ANP ) and those emerging in survival situations ( involving fight-or-flight responses, vivid traumatic memories and strong, painful emotions, the " emotional part of the personality " or EP ).

The examination of lesion data in order to deduce which brain areas are essential in the normal functioning of certain aspects of cognition is called the deficit-lesion method ; this method is especially important in the branch of neuroscience known as aphasiology.

A cross-section of a normal lower human leg is shown in Fig. 8 with the various parts labeled.

Apparently, however, Miller has relied heavily on the anatomy in dogs and cats, and he has been criticized for using pathologic human material in his normal study ( Loosli, '38 ).

Nakamura ( '58 ), Verloop ( '48 ), Marchand, Gilroy and Watson ( '50 ), Von Hayek ( '53 ), and Tobin ( '52 ) have all claimed their normal but relatively nonfunctional existence in the human being.

We have consoled ourselves with the thought that this is a normal human reaction and is one of the consequences of any decision in an adversary proceeding.

The attributes run from-25 ( normal human level ), through-10 ( normal level for a denizen of the Courts of Chaos ) and 0 ( normal level for an inhabitant of Amber ), upwards without limit.

Of the 22 standard amino acids, 9 are called essential amino acids because the human body cannot synthesize them from other compounds at the level needed for normal growth, so they must be obtained from food.

Under normal unstressed conditions, the human adrenal glands produce the equivalent of 35 – 40 mg of cortisone acetate per day.

The gain of a good quality full-range audio amplifier will be essentially flat between 20 Hz to about 20 kHz ( the range of normal human hearing ).

As a normal human digestive tract does not contain any anti-oligosaccharide enzymes, consumed oligosaccharides are typically digested by bacteria in the large intestine.

It was also suggested that individual genes are likely to have only a small effect and to be involved in some aspect related to the disorder ( and a broad range of " normal " human behavior ) rather than the disorder per se.

Candida species are frequently part of the human body's normal oral and intestinal flora.

Smallvilles Kent is particularly inwardly conflicted as he attempts to live the life of a normal human being, while keeping the secret of his alien heritage from his friends.

The consensus, however, in position statements from the American Psychiatric Association, American Psychological Association and other institutions in many other countries, is that the research and clinical literature demonstrate that homosexuality is a normal and positive variation of human sexuality, and that any social exclusion or difficulties with homosexuality are a problem of society.

In a recent article about the debate in the San Francisco Chronicle, Robbins notes that under the new guidelines, certain responses to grief could be labeled as pathological disorders, instead of being recognized as being normal human experiences.

In the future, as morality continues to degenerate, human life will continue to shorten to the point where the normal life span is 10 years, with people reaching sexual maturity at five

The soybean oil emulsion does not harm normal human cells, or the cells of most other higher organisms, with the exceptions of sperm cells and blood cells, which are vulnerable to nanoemulsions due to the peculiarities of their membrane structures.

He then re-calibrated his scale using the melting point of ice and normal human body temperature ( which were at 30 and 90 degrees ); he adjusted the scale so that the melting point of ice would be 32 degrees and body temperature 96 degrees, so that 64 intervals would separate the two, allowing him to mark degree lines on his instruments by simply bisecting the interval six times ( since 64 is 2 to the sixth power ).

It is for this reason that normal human body temperature is approximately 98 ° ( oral temperature ) on the revised scale ( whereas it was 90 ° on Fahrenheit's multiplication of Rømer, and 96 ° on his original scale ).

For instance, the human CFTR gene, which encodes a protein that transports chloride ions across cell membranes, can be dominant ( A ) as the normal version of the gene, or recessive ( a ) as a mutated version of the gene.

This is one of the few natural sources of carbon monoxide production in the human body, and is responsible for the normal blood levels of carbon monoxide even in people breathing pure air.

Several works of fiction portray a future in which human cloning has become the normal process of reproduction for various reasons.

On one occasion, Iceman suffered a severe chest injury while in his ice form and was able to heal himself by converting back into his normal human form.