Single-stranded

Single-stranded DNA is usually expanded to double-stranded in infected cells.

Single-stranded DNA-binding protein, or SSB, binds to single-stranded regions of DNA to prevent premature annealing, to protect the single-stranded DNA from being digested by nucleases, and to remove secondary structure from the DNA to allow other enzymes to function effectively upon it.

Single-stranded DNA is produced during all aspects of DNA metabolism: replication, recombination and repair.

** Single-stranded RNA satellite viruses

** Single-stranded satellite DNAs

** Single-stranded satellite RNAs

Single-stranded RNA replication involves RNA-dependent RNA synthesis which meant that virus-coding enzymes would make partial double-stranded RNA.