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In the soap's anniversary year, the longest standing character, Julia Parsons suffered with Lyme Disease and viewers saw the effect of the disease, such as memory loss and leaving granddaughter Chloe at a zoo.

Also, popular characters Michelle Corrigan and Ruth Pearce left the show, with Michelle going into the Army and Ruth moved to Boston in the USA.

2010 also saw the return of Dr. Joe Fenton, who left in 2008, persuading Ruth to move to America.