Page "Multiple sclerosis" Paragraph 23

Apart from demyelination, the other pathologic hallmark of the disease is inflammation.

According to a strictly immunological explanation of MS, the inflammatory process is caused by T cells, a kind of lymphocyte.

Lymphocytes are cells that play an important role in the body's defenses.

In MS, T cells gain entry into the brain via disruptions in the blood – brain barrier.

Evidence from animal models also point to a role of B cells in addition to T cells in development of the disease.