Caveolae are small ( approx.

Caveolae are one source of clathrin-independent raft-dependent endocytosis.

Caveolae are also involved in regulation of channels and in calcium signaling.

Caveolae, on the other hand, are flask shaped invaginations of the plasma membrane that contain caveolin proteins and are the most readily-observed structures in lipid rafts.

* Caveolae can be used for entry to the cell by some pathogens and so they avoid degradation in lysosomes.

* Caveolae have a role in the cell signaling, too.

* Caveolae can also serve as mechanosensors in various cell types.

* Caveolae also participate in lipid regulation.

Really, you are most indiscreet to drive him here yourself '', he said, frowning with displeasure.

Accidental war is so sensitive a subject that most of the people who could become directly involved in one are told just enough so they can perform their portions of incredibly complex tasks.

Now we must become vague, for we are approaching one of the nation's most guarded secrets.

These things are important to almost all Persians and perhaps most important to the most ordinary.

The men crying love poems in an orchard on any summer's night are as often as not the lutihaw, mustachioed toughs who spend most of their lives in and out of the local prisons, brothels, and teahouses.

The most effective political inventions seem to make maximum use of natural harbors and are aware that restraining breakwaters can play only a minor part in the whole scheme.

The most primitive feelings are rudimentary value feelings, both positive and negative: a desire to appropriate this or that part of the environment into oneself ; ;

Our most elemental and unavoidable impressions, he says, are those of being involved in a large arena of powers which have a longer past than our own, which are interrelated in a vast movement through the present toward the future.

they are the most valuable of commodities -- and the most salable, for their demand far exceeds supply.

True, ideas are important, perhaps life's most precious treasures.

Its ontological status is itself most tenuous because apart from individual men, who are its `` matter '', tradition, the `` form '' of society exists only as a shared perception of truth.

The ingredients of Faulkner's novels and stories are by no means new with him, and most of the problems he takes up have had the attention of authors before him.

nor is there need to add that among them are some of the most highly individualized and most successful of his characters.

The problem is rather to find out what is actually happening, and this is especially difficult for the reason that `` we are busily being defended from a knowledge of the present, sometimes by the very agencies -- our educational system, our mass media, our statesmen -- on which we have had to rely most heavily for understanding of ourselves ''.

The men who speculate on these institutions have, for the most part, come to at least one common conclusion: that many of the great enterprises and associations around which our democracy is formed are in themselves autocratic in nature, and possessed of power which can be used to frustrate the citizen who is trying to assert his individuality in the modern world ''.

and, `` I do think that families are the most beautiful things in all the world '', burst out Jo some five hundred pages later in that popular story of the March family, which had first appeared when Henrietta was eight ; ;

By the same test predispositions destructive of human personality exercise their most sinister impact, with the result that men of good will are often trapped and nullified.

I assume that the number of readers of this anthology who regard themselves as morally perfect is small, and that most readers are willing to consider procedures by which they may gain more insight into themselves and better understanding of others.

This understanding, of course, may in its turn take many forms and some of these -- especially those most interesting to the student of comparative literature -- are essentially historical.

In this essay, we are, along with most historians, interested in the more general or more inclusive ideas, that are so to speak `` writ large '' in history of literature where they recur continually.

This almost trivial example is nevertheless suggestive, for there are some elements in common between the antique fear that the days would get shorter and shorter and our present fear of war.

They are presumed to have plunged to a common grave in this fatal embrace.

A common meeting ground is desirable for those nations which are prepared to assist in the development effort.

claims are properly disposed of according to norms common to all parties.

What we have in mind does have something in common with the goals of psychoanalysis and with the methods by which they are sought.

Furthermore, in certain respects, there are norms common to colleges and universities across the country.

History has demonstrated many times that concerts of nations based solely on the negative spur of common danger are unlikely to survive when the external danger ceases to be dramatically urgent.

By comparison, Stone Harbor bird sanctuary's allies seem less formidable, for aside from the Audubon Society, they are mostly the snowy, common and cattle egrets and the Louisiana, green, little blue and black-crowned herons who nest and feed there.

Bridges, tunnels and ferries are the most common methods of river crossings.

So be it -- then we must embark on a crash program for 200-megaton bombs of the common or hydrogen variety, and neutron bombs, which do not exist but are said to be the coming thing.

These problems are not local to Rhode Island, but are recognized as common to all states.

The uniform fiscal year ensures conformance with another common sense rule, that of having cash in the bank before checks are drawn.

Important considerations common to each type of shelter are: 1.

Certain pianistic traits are common to all five Schnabelian renditions, most notably the `` Schnabel trill '' ( which differs from the conventional trill in that the two notes are struck simultaneously ).

The most common are the twist drill, the solid center shaft with interchangeable cutting blades, the double spur bit, and the power wood bit.

Moreover, if Af and Af are two planes intersecting in a line l, tangent to Q at a point P, the two free intersections of the image curves Af and Af must coincide at P', the image of P, and at this point Af and Af must have a common tangent l'.

The common ultimate values, ends and goals fostered by religion are a most important factor.

The question may be raised whether or not we are dealing with a common factor in anxiety and compulsivity.

But the major portions of the total costs of a utility business are common or joint to all, or nearly all, classes of customers ; ;

The general basis on which these common costs are assigned to differently measured units of service will be illustrated by the following highly simplified problem of an electric-utility cost analysis.

Plate 12 illustrates four examples, which are Ripe or Late Geometric work of common spirit but of different schools.

That a writer who is gay cannot be serious is a common professional illusion, sedulously fostered by all too many academics who mistakenly believe that their frivolous efforts should be taken seriously because they are expressed with that dreary solemnity which is the only mode of expression their authors are capable of.