Despite extensive attempts to obtain highly pure reagents, serious difficulty was experienced in obtaining reproducible rates of reaction.

Despite extensive oil and gas resources, diamonds, hydroelectric potential, and rich agricultural land, Angola remains poor, and a third of the population relies on subsistence agriculture.

Despite extensive internationally financed programs to upgrade the harbors at Moroni and Mutsamudu, by the early 1990s only Mutsamudu was operational as a deepwater facility.

Despite an extensive manhunt and an ongoing FBI investigation, the perpetrator has never been located or positively identified.

Despite extensive traditional medicinal use, melissa oil was initially prohibited by the International Fragrance Association ( IFRA )' s 43rd amendment, but this restriction appears to have been revisited and relaxed in the 44th amendment.

Despite extensive research into the interaction of modafinil with a large number of neurotransmitter systems, a precise mechanism or set of mechanisms of action remains unclear.

Despite being a time of great attrition for the religion in England before Catholic Emancipation in the 19th century, the recusant period reaped an extensive harvest of saints and martyrs.

Despite extensive constitutional protections, the Karimov government has actively suppressed the activities of political movements, continues to ban unsanctioned public meetings and demonstrations, and continues to suppress opposition figures.

Despite the extensive intervention of central banks, including partial and total nationalization of major European banks, the crisis of sovereign debt became particularly acute, first in Iceland, though as events of the early 2010s would show, it was not an isolated European example.

Despite the extensive classical art galleries and museums in the city, there is also a contemporary arts scene that has become increasingly prominent in recent times.

Despite his extensive knowledge of ancient history, classics, archaeology and what would be termed today cultural anthropology, he apparently had not even read enough in his nominal major to pass the required examination.

Despite her extensive research, she concluded " it is

Despite extensive research, no trace of documentation of the saying as Murphy's law has been found before 1951 ( see above ).

Despite active research spanning five decades, extensive regulatory actions, and an effective ban on their production since the 1970s, PCBs still persist in the environment and remain a focus of attention.

Despite such associations and contrary to stated Social Democratic Party policy, Sweden had in fact secretly maintained extensive military co-operation with NATO over a long period, and was even under the protection of a US military security guarantee ( see Swedish neutrality during the Cold War ).

Despite this, Bizet kept on good terms with his mother-in-law and maintained an extensive correspondence with her.

Despite Binet's extensive research interests and wide breadth of publications, today he is most widely known for his contributions to intelligence.

Despite an extensive tour and an appearance on Late Night with Conan O ' Brien, the album was not commercially successful, and when the label folded, the band and the label parted ways.

Despite the extensive cuts, the film was still negatively received by audiences, and remained an object of extreme controversy.

Despite extensive police resources channelled towards their capture, a wall of silence created by a mixture of fear and respect in the Shankill community, provided few leads that could be followed.

Despite the extensive project, builders retained the shell of the 1809 – 1812 building.

Despite extensive promotion by Benson, Home At Last generally received negative reviews, including that of Rupert Loydell who described it as " a disorganised, half-produced, and ultimately unsatisfying hotchpotch of songs ".

Despite extensive vaccination in many regions, it remains a major disease of dogs.

Despite his lack of an extensive formal education, Brock appreciated its importance.

Despite numerous searches, the city has never been found.

Despite systematic searches since 1931,, they have never been observed, and could very well not exist.

Despite a month of searches by the Civil Air Patrol ( CAP ) and others, Fossett could not be found, and the search by CAP was called off on October 2, 2007.

Despite repeated and extensive searches of the area nothing was ever found.

Despite the seizure of his computer equipment ; searches of his business, person, and home ; grand jury investigations ; FBI and ATF questioning ; facing years in prison and hundreds of death threats ; he did not reveal the identities of members of the Earth Liberation Front and Animal Liberation Front movements.

Despite repeated searches, the rest of the archive, including the third milk can, was never found.

Despite the apparent destruction of the comet, there were a number of searches for it during the later 20th century.

Despite exhaustive research, including searches of census records, voting rosters, and death records, nothing has been found to substantiate the existence of this group except for a few gravestones in the Columbia Cemetery where several of the surnames are found.

" Despite its natural timidity and the distress that other beings ' anger, fear and pain cause it, Prilicla uses its empathic ability in prolonged searches for survivors of space combat and accidents.

Despite exhaustive searches, Isabella Miller's body was not recovered for several days.

Despite searches, no planets are currently known to transit the star from the perspective of Earth, making it difficult to study their properties.

Despite the fact that no specific documentation has been found in sales literature ( on internet searches ), the January 2011 issue of " The Self-Starter ", the official magazine of the Cadillac-La Salle Club, lists a 1946 model 6267D Convertible for sale with " hydraulic windows ".

Despite numerous searches for his body on Saddleworth Moor, it has yet to be found.

Despite subsequent searches, her grave remains undiscovered.

Despite the unpopularity, in an example of Rule 34, pornographic fan art of the character —" some with a remarkable degree of verisimilitude to the real thing ", according to CBS News — appeared frequently in results for Internet searches of " Erin Esurance ", also likely contributing to the decision.

Despite several efforts, searches for verifiable physical evidence have been futile, as the only evidence for the existence of the mapinguari is anecdotal.

Despite extensive searches no trace of the ' plane or its crew was found.

Despite the danger, the Rebbe refused to leave his followers and made no effort to save himself from further searches.