Farbenindustrie AG at the Farbwerke Hoechst ( it is synthesised from 1, 1-diphenylbutane-2-sulfonic acid and dimethylamino-2-chloropropane ) who were looking for a synthetic opioid that could be created with readily available precursors, to solve Germany's opium shortage problem.

Arsphenamine was originally called " 606 " because it was the sixth in the sixth group of compounds synthesized for testing ; it was marketed by Hoechst AG under the trade name Salvarsan in 1910.

The former Hoechst AG and today's Industriepark Höchst

Hoechst AG () was a German chemicals then life-sciences company that became Aventis Deutschland after its merger with France's Rhône-Poulenc S. A. in 1999.

For the international market the name was simplified to " Farbwerke Hoechst AG ".

Until 1925 the Hoechst AG was independent.

In 1916, the Hoechst AG was one of the co-founders of IG Farben, a pressure group of Germany's chemicals industry to gain industrial power during and after World War I.

By 1953 Hoechst had acquired parts of Knapsack-Griesheim, Kalle AG, Behring Werke, Wacker Chemie and Ruhr Chemie, among others.

1994 ( September 17 )-Pharmacists For Life International joins the international boycott, "... against the American subsidiary of Hoechst, AG Hoechst-Roussel, Hoechst-Celanese, its generic subsidiary Copley Pharmaceutical, Inc. and the agricultural Hoechst subsidiary " while asking U. S. consumers to " focus on key Hoechst drugs which have the most economic impact rather than taking an across-the-board shotgun approach " and specifically listing Altace as a boycott list item.

1998 ( December 18 )-The King Pharmaceuticals wholly owned subsidiary Monarch Pharmaceuticals, Inc. acquires ownership of U. S. distribution rights to Altace and other Hoechst products from Hoechst AG subsidiary Hoechst Marion Roussel of Kansas City, Missouri.

1999-Aventis was formed when Hoechst AG merged with Rhône-Poulenc S. A.

ca: Hoechst AG

pt: Hoechst AG

In 1998, Hoechst combined most of its industrial chemical operations in a new company, Celanese AG, and, in 1999, Hoechst spun off Celanese AG as a publicly-traded, German corporation, traded on both the Frankfurt and New York stock exchanges.

Later he worked for the chemical company Meister Lucius und Brüning ( today Hoechst AG ).

* Hoechst AG market Arsphenamine under the trade name Salvarsan, the first organic antisyphilitic, its properties having been discovered the previous fall by bacteriologist Sahachiro Hata during systematic testing in the laboratory of Paul Ehrlich ; it rapidly becomes the world's most widely prescribed drug.

* The opioid Methadone is synthesized in Germany by scientists working at Hoechst AG.

The company, originally a split-off from the Hoechst AG, and headquartered in the Höchst Industrial Park, produces organic light-emitting materials for OLEDs.

Due to strong immigration of citizens from Frankfurt, the confessional ( mainly catholic in former times ) and the social structure changed: in addition to the long-established village residents, mostly craftsmen and farmers, an academic affected middle-class appeared ( employees of Hoechst AG )

On April 8, 1997, after buying the remaining 43. 5 % of Roussel-Uclaf stock in early 1997, Hoechst AG ($ 30 billion annual revenue ) announced the end of its manufacture and sale of Mifegyne ($ 3. 44 million annual revenue ) and the transfer of all rights for medical uses of mifepristone outside of the U. S. to Exelgyn S. A., a new single-product company immune to antiabortion boycotts, whose CEO was former Roussel-Uclaf CEO Édouard Sakiz.

More than 2000 German companies profited from slave labour during the Nazi era, including Daimler, Deutsche Bank, Siemens, Volkswagen, Hoechst, Dresdner Bank, Krupp, Allianz, BASF, Bayer, BMW, and Degussa.

Aventis was formed in 1999 when French company Rhône-Poulenc S. A. merged with the German corporation Hoechst Marion Roussel, which itself was formed from the 1995 merger of Hoechst AG with Roussel Uclaf and Marion Merrell Dow.

The Aventis Foundation, a German charitable trust, was established in 1996 as the Hoechst Foundation with an endowment of € 50 million.

The Farben cartel was created in 1925, when Hermann Schmitz, the master organizer, with the Wall Street financial assistance, created the super-giant chemical corporation, combining six already giant German chemical companies — Badische Anilin-und Sodafabrik Ludwigshafen ( BASF ), Bayer, Agfa, Hoechst, Weiler-ter-Meer, and Griesheim-Elektron.

Upjohn ( based in Kalamazoo up until its purchase by Pharmacia in the 1990s ) made deals with the German company Hoechst, maker of Rastinon.

* The first major biotechnology contract was signed between the Massachusetts General Hospital and the German pharmaceutical firm Hoechst AG, with the corporation agreeing to pay the hospital $ 70, 000, 000 over ten years for genetic research.

Farbenkonzern and Farbwerke Hoechst were no longer protected each pharmaceutical company interested in the formula could buy the rights for commercial production of methadone for just one dollar ( MOLL 1990 ).

World War II-Various Hoechst facilities were bombed during the Oil Campaign of World War II Its managers in charge were defendants, as the other IG Farben managers, in the Nuremberg trial against the company for its role in the exploitation of enslaved laborers and for testing drugs on concentration camp prisoners.

1987-Hoechst acquired the American chemical company Celanese and formed a new Hoechst subsidiary in the US, Hoechst Celanese.

The company is now ranked in one of top 10 pharma companies, having made a string of overseas acquisitions like the Indian subsidiaries of Roche, Boehringer Mannheim, Rhone Poulenc, ICI and Hoechst Research Centre.

The company Meister Lucius & Brüning AG ( later Hoechst AG ) in Frankfurt / Höchst purchased the large leftover stocks of tuberculin and the company later began production under the leadership of Koch ’ s student Arnold Libbertz.

These Bis-benzimides were originally developed by the Hoechst AG, which numbered all their compounds so that the dye Hoechst 33342 is the 33342nd compound made by the company.

Dade's private equity owners merged the company with DuPont's in vitro diagnostics business in May 1996 and subsequently with the Behring Diagnostics division of Hoechst AG in 1997.

Aventis, the successor of Hoechst, acquired 52 % of the combined company.

Roussel Uclaf S. A. was the second largest French pharmaceutical company before it was acquired by Hoechst AG of Frankfurt, Germany in 1997, with pharmaceutical operations combined into the Hoechst Marion Roussel ( HMR ) division.

Several years later, in 1952, the company was divided into several independent firms, including BASF, Bayer and Hoechst.

HeLa cells stained for the cell nucleus DNA with the Blue Hoechst stain | Hoechst dye.

Minor groove is a binding site for the dye Hoechst stain | Hoechst 33258.

Farbenkonzern at the Farbwerke Hoechst were confiscated by the U. S. Department of Commerce Intelligence, investigated by a Technical Industrial Committee of the U. S. Department of State and then brought to the US.

The latter finding, however, can in turn be explained by that the cells that establish endometrial lesions are not of the main cell type in ordinary endometrium, but rather of a side population cell type, as supported by exhibitition of a side population phenotype upon staining with Hoechst dye and by flow cytometric analysis.

Other accolades include the Ernst Jung Prize in Medicine, Mayor ’ s Award for Excellence in Science & Technology, the Squibb Award, and the Hoechst Marion Roussel Award.

The three major firms BASF, Bayer and Hoechst produced several hundred different dyes, along with the five smaller firms Agfa, Cassella, Chemische Fabrik Kalle, Chemische Fabrik Griesheim-Elektron and Chemische Fabrik vorm.

In 1904, after having returned to Germany he proposed a nationwide merger of the producers of dye and pharmaceuticals in a memorandum to Gustav von Brüning, the senior manager at Hoechst.

Hoechst and several pharmaceutical firms refused to join.

Instead, Hoechst and Cassella made an alliance based on mutual equity stakes in 1904.

The two alliances were loosely connected with each other through an agreement between BASF and Hoechst to jointly exploit the patent on the Heumann-Pfleger indigo synthesis.

In 1908 Hoechst and Cassella acquired 88 percent of the shares of Chemische Fabrik Kalle.

As Hoechst, Cassella and Kalle were connected by mutual equity shares and were located close to each other in the Frankfurt area, this allowed them to cooperate more successfully than the Dreibund, although they also did not rationalize or consolidate their production facilities.

Under the leadership of Carl Bosch, BASF founded IG Farben with Hoechst, Bayer, and three other companies, thus losing its independence.

Detection techniques include DNA Probe, enzyme immunoassays, PCR, plating on sensitive agar and staining with a DNA stain including DAPI or Hoechst.