The reign of his son and successor Seleucus IV Philopator ( 187-175 BC ) was largely spent in attempts to pay the large indemnity, and Seleucus was ultimately assassinated by his minister Heliodorus.

Seleucus ' younger brother, Antiochus IV Epiphanes, now seized the throne.

* 175 BC: Antiochus IV Epiphanes, took possession of the Syrian throne, at the murder of his brother Seleucus IV Philopator, which rightly belonged to his nephew Demetrius I Soter.

* 175 BC – Seleucus IV Philopator, king of the Seleucid dynasty, who has ruled from 187 BC ( b. c. 217 BC )

He is succeeded by his son, Seleucus IV, who inherits an empire consisting of Syria ( including Cilicia and Palestine ), Mesopotamia, Babylonia, Media and Persia.

* With the aid of the Greek statesman and historian Polybius, the son of the former Seleucid king Seleucus IV Philopator, Demetrius escapes from Rome, where he has been held as a hostage for many years, and returns to Syria to claim the throne from his nephew Antiochus V. In the resulting dispute, Antiochus V and his regent, Lysias, are overthrown and put to death.

To make matters worse for him, the Roman Senate is holding Demetrius, the son of the former king Seleucus IV and, therefore, the rightful heir to the Seleucid throne, as a hostage.

* King Seleucus IV of Syria arranges for the exchange of his brother Antiochus for Demetrius, the son of Seleucus VI, who has been a hostage in Rome following the Treaty of Apamea in 188 BC.

However, Seleucus IV is assassinated by his chief minister Heliodorus who then seizes the Syrian throne.

* Perseus of Macedonia marries Laodice, the daughter of the Seleucid king Seleucus IV.

In the mean time, Perseus builds up the Macedonian army and puts out feelers for creating an alliance with the Greek leagues, with his northern barbarian neighbours, and also with the Seleucid king Seleucus IV.

* Antiochus, first son of Seleucus IV Philopator

* Olympiodorus the Seleucid, ( c. 178 BC ), 2nd-century BC high-priest in Koile-Syria and Phoinike, commissioned by Seleucus IV Philopator

3rd century BC & 2nd century BC ), daughter of Antiochus III the Great and Laodice III, wife of Antiochus, Seleucus IV Philopator and Antiochus IV Epiphanes

2nd century BC ), daughter of Seleucus IV Philopator and Laodice IV, wife of Perseus of Macedon and later a possible wife of Demetrius I Soter

Demetrius was sent to Rome as a hostage during the reign of his father Seleucus IV Philopator and his mother Laodice IV.

Coin of Seleucus IV Philopator, stamp Ancient Greek | Greek: ( Β ) ΑΣΙΛΕΩΣ ( ΣΕ ) ΛΕΥΚΟΥ

Seleucus IV Philopator ( Greek: Σέλευκος Δ ' Φιλοπάτωρ ), ruler of the Hellenistic Seleucid Empire, reigned from 187 BC to 175 BC over a realm consisting of Syria ( now including Cilicia and Judea ), Mesopotamia, Babylonia and Nearer Iran ( Media and Persia ).

* Seleucus IV Philopator entry in historical sourcebook by Mahlon H. Smith

la: Seleucus IV Philopator

nl: Seleucus IV Philopator

* Seleucus IV Philopator ( c. 220-175 BC ), Antiochus III's successor

* Mithridates ( 215-164 BC ), succeeded his brother Seleucus IV Philopator in 175 BC under the regnal name Antiochus IV Epiphanes

Just before his death, Ptolemy V had planned to conduct a war against the Seleucid kingdom but when Cleopatra I became sole ruler, she immediately ended the war preparations directed against her brother Seleucus IV Philopator.

* Heliodorus ( minister ) a minister of Seleucus IV Philopator ca.

* Seleucus IV Philopator ( 187 – 175 BC )

Meanwhile, Demetrius I Soter, son of Seleucus IV Philopator and nephew of the late Antiochus IV Epiphanes, fled from Rome in defiance of the Roman Senate, arrived in Assyria, captured and killed Lysias and Antiochus Eupator, and usurped the throne.

Account for inactivity of Seleucus IV Philopator in Syria, who was characterized as weak and pacific, might be consisted in part by war exhaustion of Syria in this period

Laodice III bore Antiochus III eight children who were: Antiochus, Seleucus IV Philopator, Ardys, an unnamed daughter who was engaged to Demetrius I of Bactria, Laodice IV, Cleopatra I Syra, Antiochis and Antiochus IV Epiphanes born as Mithridates.

** Seleucus II Callinicus, king of the Seleucid kingdom from 246 BC

** Seleucus III, king of the Seleucid dynasty from 226 BC ( assassinated )

** Hermeias, the favourite and chief minister of the Seleucid king Seleucus III and, for a short time, chief minister to Antiochus III

* Seleucus VI Epiphanes becomes king of the Seleucid Empire following the death of his father Antiochus VIII Grypus, and defeating in battle Antiochus IX Cyzicenus.

* Seleucus V Philometor succeeds his father Demetrius II as king of the Seleucid Empire.

* Hermeias, the favourite and chief minister of the Seleucid king Seleucus III and, for a short time, chief minister to Antiochus III

* Ptolemy VI Philometor, aged 6, rules as co-regent with his mother, Cleopatra I, who, although a daughter of a Seleucid king, does not take King Seleucus IV's side and remains on friendly terms with Rome.

* The Seleucid king Seleucus III is assassinated in Phrygia by members of his army while on campaign against Attalus of Pergamon.

* Seleucus III, king of the Seleucid dynasty from 226 BC ( assassinated )

* Seleucus II Callinicus, king of the Seleucid kingdom from 246 BC

* King Attalus I Soter of Pergamum defeats Antiochus Hierax ( brother of the Seleucid king Seleucus II ) in three battles and thereby gains control over all the Seleucid domains in Anatolia except Cilicia in the southeast.

* The Seleucid king Seleucus II Callinicus undertakes an expedition into the interior of Iran to try to regain Parthia, but his efforts come to nothing.

* Seleucid king Antiochus I's eldest son Seleucus, who has ruled in the east of the kingdom as viceroy for a number of years, is put to death by his father on the charge of rebellion.

* Antiochus III the Great ( 241 – 187 BC, king 222 – 187 BC ), younger son of Seleucus II Callinicus, became the 6th ruler of the Seleucid Empire

* Antiochus makes his eldest son, Seleucus, king in the east, but he proves to be incompetent.

* With Antigonus and Demetrius now each assuming the title of king, Ptolemy, as well as Cassander, Lysimachus and Seleucus I Nicator, respond by doing the same.

* Arsinoe, daughter of Lysimachus, king of Thrace, marries Ptolemy II of Egypt as part of the alliance between Thrace and Egypt against Seleucus.

* The Macedonian King, Demetrius Poliorcetes, faces a combined attack from Lysimachus and Phyrrhus, king of Epirus, after Seleucus, Ptolemy and Lysimachus form a coalition to block plans by Demetrius to invade Asia Minor.

Stratonice bore five children to Antiochus: Seleucus ( he was executed for rebellion ), Laodice, Apama II, Stratonice of Macedon and Antiochus II Theos, who succeeded his father as king.