When the spindle checkpoint misfunctions, this can lead to chromosome missegregation, aneuploidy and even tumorigenesis.

Like Eliot, in my fantasies, I had a proud bearing and, with a skill that was vaguely continental, I would lead Jessica through an evening of dancing and handsome descriptions of my newest exploits, would guide her gently to the night's climax which, in my dreams, was always represented by our almost suffocating one another to death with deep, moist kisses burning with love.

In mammals, the sex of the offspring is determined by the sperm cell: a spermatozoon bearing a Y chromosome will lead to a male ( XY ) offspring, while one bearing an X chromosome will lead to a female ( XX ) offspring — the X chromosome.

The process of bearing witness was not intended to lead to the death of the witness, although it is known from ancient writers ( e. g. Josephus ) and from the New Testament that witnesses often died for their testimonies.

Modine has produced a variety of acid, lead, and copper bearing waste products which in previous decades were buried on site and also at a public dump a mile north east of the plant.

Like cage frequency vibration in a ball bearing, the half frequency whirl is a bearing instability that generates eccentric precession which can lead to poor performance and reduced life.

In forested areas, it was essential for rapid progress and accuracy that the lead chainman follow the correct bearing at all times, since no straightening of the chain was possible without backtracking around trees and re-measuring.

It contained a lion within a wreath of wheat ears below a red five-pointed star and above a ribbon bearing the years 681, the year of the establishment of the First Bulgarian Empire by Asparukh and 1944, the year when the Fatherland Front took power which lead to the establishment of the People's Republic of Bulgaria.

On 1 April 1998, an intact bottle bearing a lead closure similar to that recovered earlier in the year was discovered by expedition team members Bob Sheppard, Bob Creasy and Dr Michael McCarthy.

Vibration monitoring programs are proven to warn of impending failure, save money, reduce downtime, and improve safety in plants worldwide by detecting conditions such as wear and tear of bearings, shaft misalignment, rotor imbalance, gear failure or bearing fault which, if not attended to promptly, can lead to costly repairs.

He became renowned for his determination to lead from the front, for his impassive bearing under fire and for personal bravery verging on the foolhardy ( resulting in him being wounded on numerous occasions and having his horse shot from under him twice ).

It is the more serious of the two phenomena because it can lead to catastrophic failure of the bearing.

The company's only regular production item was a patented steel-backed lead bearing which was used in various high performance engines.

Ryan founded a flying service in San Diego that would lead to several aviation ventures bearing the Ryan name, including Ryan Airlines founded in 1925.

In addition, the determination of whether or not delivery actually occurred prior to death has a bearing on analyses of the mother's population, as the concentration of trace elements differ markedly between the skeletons of prepartum adult women ( before pregnancy ) and women who are lactating ; the identification of coffin birth would lead to more accurate analyses of the number of lactating women in a population or the rate of maternal mortality.

The expression a " run bearing " also derives from this style of bearing, since failure of lubrication will lead to heat build up due to friction in the bearing, eventually leading to the bearing metal liquefying and running out of the pillow block.

Berger retired on lap three with a broken piston whilst on lap 10 second place Michele Alboreto's wheel bearing broke and Nelson Piquet retired with a broken turbo pipe, handing the lead to Alain Prost from Teo Fabi and Stefan Johansson.

Liver blood stagnation may lead to amenorrhea, blood clotting, or a bearing down sensation with menstruation.

Roads from the Old Town valley lead towards the Victorian area of Clive Vale and the former village of Ore, from which " The Ridge ", marking the effective boundary of Hastings, extends north-westwards towards Battle.

) Because of MacLean's death in 1998, Lee handled the lead vocals on the MacLean songs " Alone Again Or " and " Old Man.

* Bryan MacLean: rhythm guitar, vocals ( lead vocals on " Old Man " and co-lead vocals on " Alone Again Or ")

The Old Fashioned is a cocktail of choice of Don Draper, the lead character on the Mad Men television series.

Pencil, from Old French pincel, a small paintbrush, from Latin a " little tail " ( see penis — pincellus is Latin from the post-classical period ) is an artist's fine brush of camel hair, also used for writing before modern lead or chalk pencils ; the meaning of " graphite writing implement " apparently evolved late in the 16th century.

In the Old World, the first metals smelted were tin and lead.

The voyages of Christopher Columbus from 1492 to 1502 resulted in permanent contact with European ( and subsequently, other Old World ) powers, which lead to the Columbian exchange.

The price increases lead to the Old Price Riots which last for 64 days.

In 1942, at the age of twelve, she played a lead in Don't Feed the Animals, a play produced by the East Falls Old Academy Players.

He describes how the " Old Man of the Mountain " ( Sabbah ) would drug his young followers with hashish, lead them to a " paradise ", and then claim that only he had the means to allow for their return.

In one collaboration, first-generation bluegrass fiddler Vassar Clements, progressive mandolin player David Grisman, Grateful Dead frontman Jerry Garcia ( on banjo ), and Peter Rowan on lead vocals played in the band called Old and in the Way.

These streets all lead up to Stirling Castle and are the favourite haunt of tourists who stop off at the Old Town Jail, Mar's Wark, Argyll's Lodging and the castle.

Old individuals are also capable of producing aerial roots ( chi chi ) on the undersides of large branches in response to disturbances such as crown damage ; these roots can lead to successful clonal reproduction upon contacting the soil.

By 1952 the popularity of the character convinced Dell to give Scrooge a try-out as a lead character in the seminal " Only a Poor Old Man ", a story Barks expert Michael Barrier has termed a masterpiece.

She is one of the most nominated actresses in Emmy Award history with a total of 13 nominations, seven for supporting actress in a comedy series for Seinfeld, and a combined six nominations for lead actress in a comedy series for The New Adventures of Old Christine and Veep.

Image: Old Lancaster Pike in Hockessin. JPG | Old Lancaster Pike in Hockessin, where historic homes lead to the business / retail area.

These forms would eventually lead to the standard pyramid tomb in the later Old Kingdom.

Each year on Patriots ' Day ( traditionally April 19 ; since 1969, observed on the 3rd Monday in April as part of a 3-day Patriots ' Day weekend ), the Acton Minutemen lead a march from Acton Center to the Old North Bridge in Concord.

The mines immediately east of the town, in what has been called the Old Lead Belt, were at one time one of the largest sources of lead in the United States.

The town is located in Old Lead Belt, formerly a large lead mining district.

A dark Western that deals frankly with the uglier aspects of violence and the myth of the Old West, it stars Eastwood in the lead role, with Gene Hackman, Morgan Freeman, and Richard Harris.

At the time of the Fanchers ' arrival, the Utah Territory was organized as a theocratic democracy under the lead of Brigham Young, who had established colonies along the California Trail and Old Spanish Trail.

These mining operations generally focused on discovering either lead or silver ore ; the company appointed Philip Francois Renault as commander of the mines, and in 1723 Boisbriand ceded land to Renault in Washington County ( in an area now known as the Old Mines ) and in the Mine La Motte area.