Within ninety days ( but usually less than a month ) of infection a painless but distinctive ' mother yaw ' appears, which is a painless nodule which enlarges and becomes warty in appearance.

SCC of the skin begins as a small nodule and as it enlarges the center becomes necrotic and sloughs and the nodule turns into an ulcer.

Studies over several years covering the key mineral area of the Central Pacific resulted in a technical study on biodiversity, species ranges and gene flow in the abyssal Pacific nodule province, with emphasis on predicting and managing the impacts of deep seabed mining A workshop at Manoa, Hawaii, in October 2007 produced a rationale and recommendations for the establishment of " preservation reference areas " in the Clarion-Clipperton Zone, where nodule mining would be prohibited in order to leave the natural environment intact.

The typical rheumatoid nodule may be a few millimetres to a few centimetres in diameter and is usually found over bony prominences, such as the olecranon, the calcaneal tuberosity, the metacarpophalangeal joint, or other areas that sustain repeated mechanical stress.

They earned the moniker " indeterminate " because they maintain an active apical meristem that produces new cells for growth over the life of the nodule.

Having discussed with colleagues the immunological nature of the " Aschoff nodule " ( an intracardiac, endomyocardial collection of myocytes and inflammatory cells ) in rheumatic fever, Albert had mulled over the nature of the antigens and antibodies that were involved in its formation.

With time, gummas eventually undergo fibrous degeneration, leaving behind an irregular scar or a round fibrous nodule.

If the nodule is benign, patients may receive thyroxine therapy to suppress thyroid-stimulating hormone and should be reevaluated in 6 months.

The promise of nodule exploitation was one of the main factors that led developing nations to propose that the deep seabed beyond the limits of national jurisdiction should be treated as a “ common heritage of mankind ”, with proceeds to be shared between those who developed this resource and the rest of the international community.

* Uninodular ( struma uninodosa ): can be either inactive or a toxic nodule

The initial pathologic process in nodule formation is unknown but may be essentially the same as the synovitis, since similar structural features occur in both.

The nodule has a central area of fibrinoid necrosis that may be fissured and which corresponds to the fibrin-rich necrotic material found in and around an affected synovial space.

Among these were the teeth of a reptile / mammal hybrid, Plagiaulax dawsoni, " found " in 1891 ( and whose teeth had been filed down in the same way that the teeth of Piltdown man would be some 20 years later ), the so-called " shadow figures " on the walls of Hastings Castle, a unique hafted stone axe, the Bexhill boat ( a hybrid seafaring vessel ), the Pevensey bricks ( allegedly the latest datable " finds " from Roman Britain ), the contents of the Lavant Caves ( a fraudulent " flint mine "), the Beauport Park " Roman " statuette ( a hybrid iron object ), the Bulverhythe Hammer ( shaped with an iron knife in the same way as the Piltdown elephant bone implement would later be ), a fraudulent " Chinese " bronze vase, the Brighton " Toad in the Hole " ( a toad entombed within a flint nodule ), the English Channel sea serpent, the Uckfield Horseshoe ( another hybrid iron object ) and the Lewes Prick Spur.

Often, the pigmentation scars can be avoided simply by avoiding aggravation of the nodule or cyst.

However, if the benign nodule is inhibiting the patient's normal functions of life ; such as breathing, speaking, or swallowing, the thyroid may need to be removed.

Often the chert nodule will be split in half to create two cherts with a flat circular face for use in walls constructed of lime.

However, until a better system of classification has been perfected, it appears as if we have to be content with the cross-inoculation grouping as a convenient and workable method of classifying root nodule bacteria into species.

Serological methods can be used as a means of obtaining information on the distribution of strains that can be recognised within an area, on widely separated areas, on the plant or within a nodule.

The calcified nodule can be within the lung, hila, or mediastinum.

A more severe form of infection produces diffuse swelling of a limb, which, unlike the papule or nodule, can be painful and accompanied by fever.

The microstructure of some demantoids is believed to be affected by the presence of ' horsetails ' ( the ' horsetail ' typically originates towards the centre of the nodule, with the fibres branching out and radiating towards the surface ), whereas horsetail-free demantoids from other sources frequently display flat crystal faces.

Mast cell tumors are known among veterinary oncologists as ' the great pretenders ' because their appearance can be varied, from a wart-like nodule to a soft subcutaneous lump ( similar on palpation to a benign lipoma ) to an ulcerated skin mass.

* The painful point can be felt as a nodule or band in the muscle, and a twitch response can be elicited on stimulation of the trigger point.

Usually there is a taut band in muscles containing trigger points, and a hard nodule can be felt.

If the chemistry is right, the organism ( or fragment of organism ) can act as a nucleus for the precipitation of minerals such as siderite, resulting in a nodule forming around it.

Less commonly, a single nodule is responsible for the excess hormone secretion, called a " hot " nodule.

Although leghemoglobin was once thought to provide a buffer for nodule oxygen, recent studies indicate that it stores only enough oxygen to support nodule respiration for a few seconds.

See vocal fold nodule for more information on nodules.

Like most members of their family, lupins can fix nitrogen from the atmosphere into ammonia via a rhizobium-root nodule symbiosis, fertilizing the soil for other plants.

Following throat surgery to remove a nodule from a vocal cord, Good holed up for three weeks in a hotel in Whistler to work on songs.

Indeed high nitrogen content blocks nodule development as there is no benefit for the plant of forming the symbiosis.

The energy for splitting the nitrogen gas in the nodule comes from sugar that is translocated from the leaf ( a product of photosynthesis ).

Investigations into the mechanisms of nodule formation showed that the ENOD40 gene, coding for a 12 – 13 amino acid protein, is up-regulated during nodule formation.

Nod factors act by inducing changes in gene expression in the legume, most notable the nodulin genes, which are needed for nodule organogenesis.

According to an interview, Garlin developed a harmful nodule in his throat due to the long process of recording his voice for this role.

If an infected person happens to have a chest X-ray following granuloma formation, the nodule may be large enough to resemble lung cancer on the X-ray and require a biopsy for a pathologic assessment.

An ugly reef is this of the Dhu Heartach ; no pleasant assemblage of shelves, and pools, and creeks, about which a child might play for a whole summer without weariness, like the Bell Rock or the Skerryvore, but one oval nodule of black-trap, sparsely bedabbled with an inconspicuous fucus, and alive in every crevice with a dingy insect between a slater and a bug.

This is where new nodule tissue is formed which will later differentiate into the other zones of the nodule.

From this microcolony, the bacteria enter the developing nodule through a structure called an infection thread, which grows through the root hair into the basal part of the epidermis cell, and onwards into the root cortex ; they are then surrounded by a plant-derived membrane and differentiate into bacteroids that fix nitrogen.

A variable degree of ventricular enlargement, either obstructive ( e. g. by a subependymal nodule in the region of the foramen of Monroe ) or idiopathic in nature.

* Sertoli cell nodule

When the nod factor is sensed by the root, a number of biochemical and morphological changes happen: cell division is triggered in the root to create the nodule, and the root hair growth is redirected to wind around the bacteria multiple times until it fully encapsulates 1 or more bacteria.

In anatomy and neuroscience, a dorsal root ganglion ( or spinal ganglion ) is a nodule on a dorsal root that contains cell bodies of neurons in afferent spinal nerves.

Till and McCulloch called the nodules ' spleen colonies ', and speculated that each nodule arose from a single marrow cell: perhaps a stem cell.

In later work, Till and McCulloch were joined by graduate student Andy Becker, and demonstrated that each nodule did indeed arise from a single cell.