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Page "Human skeleton" ¶ 16
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Bone and cells
Bone cells also release a hormone called osteocalcin, which contributes to the regulation of blood sugar ( glucose ) and fat deposition.
* Bone lining cells are essentially inactive osteoblasts.
Bone is formed by the hardening of this matrix entrapping the cells.
Bone is resorbed by osteoclast cells ( which derive from the bone marrow ), after which new bone is deposited by osteoblast cells.
Bone marrow has been found to be one of the rich sources of adult stem cells which have been used in treating several conditions including Spinal cord injury, Liver Cirrhosis, Chronic Limb Ischemia and Endstage heart failure.
Bone marrow transplantation is, as of 2009, the only established use of stem cells.
Bone tumors may be classified as " primary tumors ", which originate in bone or from bone-derived cells and tissues, and " secondary tumors " which originate in other sites and spread ( metastasize ) to the skeleton.
Specification of primordial germ cells in the laboratory mouse is initiated by high levels of Bone Morphogenetic Protein ( BMP ) signaling, which activates expression of the transcription factors Blimp-1 / Prdm1 and Prdm14.
Bone marrow ablation is a process whereby the human bone marrow cells are eliminated in preparation for a bone marrow transplant.
Bone marrow suppression or myelotoxicity ( adjective myelotoxic ) or myelosuppression, is the decrease in cells responsible for providing immunity, carrying oxygen, and those responsible for normal blood clotting.
1: Olfactory bulb 2: Mitral cell s 3: Bone 4: Nasal Epithelium 5: Glomerulus ( olfaction ) | Glomerulus 6: Olfactory receptor | Olfactory receptor cells
* Bone pain, joint pain ( caused by the spread of " blast " cells to the surface of the bone or into the joint from the marrow cavity )
Bone tissue is predominantly extracellular matrix, rather than living cells, and the few blood vessels needed to support this low metabolism are only able to bring a limited number of immune cells to an injury to fight infection.
Bone Marrow Stem cells especially the CD34 + cells have been found to be relatively more in men compared to women in the reproductive age group among spinal cord injury patients.
Bone marrow failure is caused by the accumulation of hairy cells and reticulin fibrosis in the bone marrow, as well as by the detrimental effects of dysregulated cytokine production.
*-" Cartilage and Bone and Bone Histogenesis: cells of *-" Cartilage and Bone and Bone Histogenesis: compact bone "* = D Histology at ou. edu
Bone marrow aspirates of 22 % of patients with localized prostate cancer ( stage B, 0 / 5 ; Stage C, 2 / 4 ), and 36 % patients with metastatic prostate cancer ( Stage D1, 0 / 7 patients ; Stage D2, 4 / 4 patients ) had antigen-positive cells in their bone marrow.
* Bone marrow / stem cells

Bone and release
The 1980s also saw the birth of the grunge genre, with the arrival of such bands as Soundgarden, Green River, Melvins, Screaming Trees, Malfunkshun, Skin Yard, The U-Men, Blood Circus, Nirvana, Tad, Mudhoney, Mother Love Bone and Alice in Chains ( who formed in 1987, but did not release their first album until three years later ).
Seattle group Green River chose to record their Dry as a Bone EP for Pavitt's new label in June 1986 ; Pavitt couldn't afford to release it until the following year.
On the 14th of April 2011, Bone Thugs-n-Harmony member Krayzie Bone announced he left the group after 20 years citing uncontrollable circumstances along with Wish Bone to pursue their solo careers further and release records on their label, The Life Entertainment.
Almost immediately following the release of Dry As a Bone, the group re-entered the studio to begin production on its first full-length album, Rehab Doll.
Mother Love Bone quickly rose to popularity in the Seattle scene, and were about to release its debut album in 1990, when Wood fatally overdosed on heroin.
After a tour with Overkill they added Fritha Jenkins on violin and keyboard and a second guitarist in the shape of baxter's friend Dave Pugh, allowing for a more Folk-based sound on their follow-up release A Burnt Offering for the Bone Idol in 1992.
Layton's summer 1991 release of " Without You ( One and One )" followed, again produced by Driza Bone.
1987 saw the release of Close to the Bone and the single " Get That Love ", which climbed to No. 31 in the US but failed in the UK.
Booth continued as a solo artist in 2004 with the release of his solo album Bone, co-written and produced by Lee Muddy Baker.
The band released the EP Come on Down in 1985 and followed it up with Dry As a Bone in 1987, the first release on Sub Pop records.
" References to the recording environment and process were made in the field-recorded interview segments made for the promotional CD release, Bone Machine: The Operator's Manual, which threaded together full studio tracks and conversation for a pre-recorded radio show format.
The music soundtrack became a cult favourite due ot the inclusion of many significant new wave acts – Patti Smith, The Pretenders, Talking Heads and Roxy Music – and it also became a collector's item for fans of English band XTC because their track " Take This Town ", written especially for the film, was for many years only available on the soundtrack LP ( until the release of Rag and Bone Buffet: Rare Cuts and Leftovers in 1990 ).
As of 2011, he and Layzie Bone of Bone Thugs-n-Harmony are planning to release a joint EP entitled FireSquad, which is set to be released late 2011 / early 2012.
The band released the EP Come on Down in 1985 and followed it up with Dry As a Bone in 1987, the first release on Sub Pop records.
Turner and Dead Fred had stints in Hawkwind before regrouping to release the albums New Anatomy, The President Tapes and the EP Blood and Bone.
Almost immediately following the release of Dry As a Bone, the group re-entered the studio in August 1987 to begin production on its first full-length album, Rehab Doll.
Though " Lady D ' Arbanville " would reach # 8 on the British charts, Mona Bone Jakon was only a modest success upon its initial release.
After " Hillbilly Bone " reached No. 1 in February, came the August release of " All About Tonight ", the lead-off single to his EP of the same name.
A student group had seized control of the Budapest political prison where Bone was held, and processed political prisoners for release.
A year after the " Bailamos " release, in 2000, Sean Paul sampled the melody of the refrain in his song " Tiger Bone " featuring Mr. Vegas on his debut album " Stage One ".

Bone and hormone
Bone building through increased secretion of osteoid is stimulated by the secretion of growth hormone by the pituitary, thyroid hormone and the sex hormones ( estrogens and androgens ).
Bone maturation is delayed with the variation of normal development termed Constitutional growth delay, but delay also accompanies growth failure due to growth hormone deficiency and hypothyroidism.
Bone growth in length is stimulated by the production of growth hormone ( GH ), a secretion of the anterior lobe of the pituitary gland.

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