[permalink] [id link]
Click chemistry is well suited to fill this niche, since click reactions are, by definition, rapid, spontaneous, selective, and high-yielding .< ref name =" pmid11433435 "> Unfortunately, the most famous " click reaction ," a cycloaddition between an azide and an acyclic alkyne, is copper-catalyzed, posing a serious problem for use in vivo due to copper ’ s toxicity .< ref name =" pmid12203546 ">
from
Wikipedia
Some Related Sentences
Click and chemistry
* Click chemistry, a chemical philosophy
Click chemistry is often cited as a style of chemical synthesis that is consistent with the goals of green chemistry.
Click chemistry was first fully described by K. Barry Sharpless of The Scripps Research Institute in 2001 < ref > and describes chemistry tailored to generate substances quickly and reliably by joining small units together.
Click chemistry is not a single specific reaction, but was meant to mimic nature, which also generates substances by joining small modular units.
A desirable Click chemistry reaction would:
Click chemistry in combination with combinatorial chemistry, high-throughput screening and building chemical libraries speeds up new drug discoveries by making each reaction in a multistep synthesis fast, efficient and predictable.
Many of the Click chemistry criteria are subjective, and even if measurable and objective criteria could be agreed upon, it is unlikely that any reaction will be perfect for every situation and application.
One of the most popular reactions within the Click chemistry concept is the azide alkyne Huisgen cycloaddition using a Copper ( Cu ) catalyst at room temperature.
Click chemistry has widespread applications.
Click chemistry has also been used for selectively labeling biomolecules within biological systems.
* Click Chemistry-a Chem Soc Rev themed issue highlighting the latest applications of click chemistry, guest edited by M G Finn and Valery Fokin.
da: Click chemistry
it: Click chemistry
Click image for details of the mineral chemistry.
Click and is
The show is entitled Click and Clack's As the Wrench Turns, and is based on the adventures of the fictional " Click and Clack " brothers ' garage at " Car Talk Plaza ".
* PBS NOVA: " The Archimedes Palimpsest " Click on " What is a Palimpsest?
( Click here then in ref below for diagram :) The paleopulmonic unidirectional airflow is in contrast to the mammalian system, in which the direction of airflow in the lung is tidal, reversing between inhalation and exhalation.
* Click ( 2006 ): February 5, 2017, is featured as the date when Adam Sandler's character becomes CEO of his architectural firm.
* Click ( 2006 ): Michael Newman uses his remote control and is unwillingly sent to 2023, among other years.
* Click, in which a man who often puts work before his family is shown a life in which work finally wins out and his family leaves him.
< div align =" center "> Pine Mountain Club is a private community that is managed by a property owners association. Click the images to see larger versions of the photos .</ div >
The WebSite for the city of Deepwater Missouri is Click Here
The total earnings amount is then divided by the number of clicks the affiliate sent to eBay and is reported as Earnings Per Click, or EPC.
Click tracks can also be essential for certain types of metal, especially if the music is played at an extremely high tempo.
The 2006 Adam Sandler film Click is the first film in which Hasselhoff plays a character, as Sandler's despicable boss.
* Click Click, a reference to a pilot's acknowledgement of a transmission by keying his mike twice, as he is otherwise occupied.
His music is still widely used in films, recent notable cases being Breakfast on Pluto, Death Proof, Lords of Dogtown, Billy Elliot, Jarhead, Moulin Rouge !, Herbie: Fully Loaded, Breaking-Up, Hot Fuzz, Click, School of Rock & Scott Pilgrim vs. the World.
Click here to see if your climbing equipment is UIAA certified or not: http :// www. theuiaa. org / certified_equipment. php This web page also provides access to a data base of climbing related products that have been recalled by the manufacturer.
LookSmart also licenses and manages ' white label ' search ad networks for clients that want to maintain their own branded content and is one of the five founding members of the IAB Click Measurement Panel.
Click of death is a term that became common in the late 1990s referring to the clicking sound in disk storage systems that signals a disk drive has failed, often catastrophically.
It is known for its chopped and screwed rap music, popularized by DJ Screw and the Screwed Up Click.
His second ex wife is Ma Barker, formerly of his crew 5 Family Click.
Click and well
Click on image for a larger version Schematic geological map of the Alps, showing the tectonic subdivision as well as the largest geological structures.
It had two singles that performed well on rock radio, " Your Disease " and " Click Click Boom ".
" as a running gag in Sandler's films The Waterboy, Little Nicky, 50 First Dates, The Longest Yard, and Bedtime Stories, as well as in a deleted scene from Click.
TV, which includes weekly instalments of video interviews with musicians, as well as a section titled Click Hear where readers can be guided to the latest music released on the internet.
Blake was a host on Current TV and starred on the TV series Fridays on Cartoon Network, Culture Click on Litton's Weekend Adventure, as well as in national television commercials for Sprite and Kinkos.
In 1996, then east coast Sales Manager, Robert Formentin sold the first Cost Per Click programs as well as the precursor to pop-ups called daughter windows to Grey Advertising for a Procter & Gamble Pampers campaign.
As well, she appeared as herself in Instant Star and in 2006 she had a mini-series on The N's The Click titled Stacey's NYC 101.
He last starred in the sitcom Everybody Hates Chris as Julius Rock, and his more modern movie appearances were alongside Adam Sandler in The Longest Yard, Click, and The Benchwarmers ( as well as the long-delayed Mike Judge film Idiocracy, where Crews played President Dwayne Elizondo Mountain Dew Herbert Camacho ).
Although their system, called Five-Speed Click, worked well, it proved an idea ahead of its time and did not catch on with the riding public.
The song was included on the setlist for Stefani's debut tour Harajuku Lovers Tour 2005, the tour's video album and the New Zealand compilation album Now That's What I Call Music 20, as well as in the 2006 comedy Click and the 2010 drama Somewhere.
The Click Five were known for appearing in matching Mod-based sharp-looking suits and ties coupled with moptop haircuts, as well as wearing bright red collared shirts underneath.
1.340 seconds.