Despite extensive attempts to obtain highly pure reagents, serious difficulty was experienced in obtaining reproducible rates of reaction.

Despite its difficulty of learning, this method remains popular in Chinese communities that use traditional Chinese characters, such as Hong Kong and Taiwan ; it is also the first method that allowed users to enter more than a hundred Chinese characters per minute.

Despite wide critical acclaim for its acts and a dedicated fanbase, Jeepster nevertheless found itself financially troubled by 2002, largely due to increasing recording and marketing costs, and difficulty cultivating the images of their acts in the eye of the general public.

Despite their inexperience as well as an increasing difficulty of the games, Ender devises new tactics and his squad soon excels and leads the competition.

Despite being the predicted winner of this year's Long Walk, having been described as " moose-like " and able to walk long distances with little difficulty, Scramm succumbs to pneumonia.

Despite the difficulty involved in constructing the road, the workers had access to a piano, gramophone, games, newspapers and magazines at the camps.

Despite having warned of the difficulty of provisioning Britain for a long war, he was blamed for the shortage of shells in the spring of 1915 – one of the events leading to the formation of a coalition government – and stripped of his control over munitions and strategy.

Despite the positive changes in the country, Bokassa had difficulty obtaining international recognition for his new government.

Despite the greater difficulty, nasotracheal intubation route is preferable to orotracheal intubation in children undergoing intensive care and requiring prolonged intubation because this route allows a more secure fixation of the tube.

Despite the fact that Britain had been caused severe difficulty by the U-Boat campaign in the First World War, the Admiralty completely ignored the threat of the submarine until the late 1930s.

Despite this newest theory of reading, Barthes remained concerned with the difficulty of achieving truly neutral writing, which required an avoidance of any labels that might carry an implied meaning or identity towards a given object.

Despite the high quality and lower difficulty of the questions, only sixteen teams attended ACF Nationals in 2001, and the future of the format seemed tenuous.

Despite the difficulty, a prompt diagnosis of DLB is important because of the risks of sensitivity to neuroleptic drugs and because appropriate treatment of symptoms can improve life for both the person with DLB and their caregivers.

Despite his popularity, Wain suffered financial difficulty throughout his life.

Despite the theoretical advantages of the reflector design, the difficulty of construction and the poor performance of the speculum metal mirrors being used at the time meant it took over 100 years for them to become popular.

Despite past attempts to repair these scars, they had difficulty in covering up those slashes ( as they found out that the painting was painted with tempera infused with diluted wax ).

Despite his rank, Travis had to recruit the men who were to serve under his command, but he had difficulty in finding willing colonists to enlist as regulars, because the majority wished to remain in their local militia units.

Despite continuing difficulty with arthritis in his wrists, Heilmann hit. 333 for the Reds in 1930 with 68 extra base hits, 19 home runs, and 91 RBIs.

Despite the difficulty of finding an opponent for Lingle, former State Senator Randy Iwase decided to run for Governor.

Despite these differences, communication between Auslan users from different regions poses little difficulty for most Deaf Australians, who often become aware of different regional vocabulary as they grow older, through travel and Deaf community networks, and because Deaf people are so well practised in bridging barriers to communication.

Despite securing his patent, Howe had considerable difficulty finding investors in the United States to finance production of his invention, so his elder brother Amasa Bemis Howe traveled to England in October 1846 to seek financing.

Despite vast land holdings that were worth a fortune, changing money values on mortgages held on the tracts of land sold and a depressed land market caused Phelps to get into financial difficulty.

Despite his difficulty in establishing his reputation, he attracts Madame Nadezhda von Meck as his patron.

Despite the work done by Walter and Michaux, current researchers have had difficulty interpreting their circumscriptions of species boundaries.

Unfortunately in the literature the definition is given in two variants: Despite the fact that Bernoulli defined B < sub > 1 </ sub > = 1 / 2 ( now known as " second Bernoulli numbers "), some authors set B < sub > 1 </ sub > = − 1 / 2 (" first Bernoulli numbers ").

Despite the ambiguity of Locke's definition of property, which limited property to " as much land as a man tills, plants, improves, cultivates, and can use the product of ", this principle held great appeal to individuals possessed of great wealth.

" Despite this ruling, a bill to add discrimination based on subculture affiliation to the definition of hate crime in British law was not presented to parliament.

Despite the regular holding of relatively free and fair elections to the National Assembly, Kuwait is not a democracy by the usual definition of the term because the prime minister is not responsible to parliament.

Despite its seemingly straightforward definition, the concept of the phenotype has hidden subtleties.

Despite the park administration's definition of the active delta as beginning at Porto Viro, there is another active channel upstream from it at Santa Maria in Punta, where the Fiume Po divides into the Po di Goro and the Po di Venezia.

Despite the lack of universal agreement upon definition for determining a stream's source, the United States Geological Survey, the National Geographic Society, and the Smithsonian Institution agree that a stream's source should be considered as the most distant point ( along watercourses from the river mouth ) in the drainage basin from which water runs.

Despite this very general definition, in the Prior Analytics, Aristotle limits himself to categorical syllogisms, which consist of three categorical propositions.

Despite its progress, there are still many fundamental problems faced by this field as " unlike medicine, evaluation is not a discipline that has been developed by practicing professionals over thousands of years, so we are not yet at the stage where we have huge encyclopaedias that will walk us through any evaluation step-by-step ", or provide a clear definition of what evaluation entails ( Davidson, 2005 ).

Despite this new approach, their definition of a Basque is still open to interpretation, with both Roberto López Ufarte and Benjamín being overlooked despite having Basque parents.

Despite the importance of some of his theories, Barbon's work ( especially A Discourse of Trade ) has been criticised for an excess of " definition and classification " instead of analysis and a disjointed style which lacked rigour.

Despite popular recognition of Rizal as " the Philippine national hero ", the title itself has no explicit legal definition in present Philippine law.

Despite this, many manufacturers are beginning to avoid the segment definition for their products, as speed and basic functionality alone are often not sufficient to differentiate the many features that the devices are capable of.

Despite this definition the country did not have a state religion until 1973, when a new constitution, more democratic and less secular, was adopted.

Despite the fact that some broadcasters, such as the BBC, consider Super16 a " non-HD " format, John Inwood believed that footage from his camera was not only sufficient to air in high definition, it " looked terrific.

Benjamin Madley wrote: " Despite over 170 years of debate over who or what was responsible for this near-extinction, no consensus exists on its origins, process, or whether or not it was genocide " however, using the " U. N. definition, sufficient evidence exists to designate the Tasmanian catastrophe genocide.

Despite this ambiguity, there does seem to be emerging some definition to what constitutes the contemporary visionary art ' scene ' and which artists can be considered especially influential.

Despite that, the definition of international students varies in each country in accordance to their own national education system.

Despite the centrality of the idea of " breeds " to animal husbandry, there is no scientifically accepted definition of the term.

Despite converging agreement about the definition of persistent vegetative state, recent reports have raised concerns about the accuracy of diagnosis in some patients, and the extent to which, in a selection of cases, residual cognitive functions may remain undetected and patients are diagnosed as being in a persistent vegetative state.

Despite there not being much change in the basic definition, 49 new metropolitan areas were formed as a result of the new rules for them.

Despite this RFC 2152 is quoted as the definition of UTF-7 in the IANA's list of charsets.

Despite these attempts calculus continued to be developed using non-rigorous methods until around 1830 when Augustin Cauchy, and later Bernhard Riemann and Karl Weierstrass, redefined the derivative and integral using a rigorous definition of the concept of limit.

Despite its name, it is not a county by the standard definition, as all municipal services are handled by a single level of government.