Despite being effective against drug resistant parasites, halofantrine is not commonly used in the treatment ( prophylactic or therapeutic ) of malaria due to its high cost.

Despite some evidence showing that all the major therapeutic orientations are about of equal effectiveness, there remains much debate about the efficacy of various forms treatment in use in clinical psychology.

Despite advances in technology and understanding of biological systems, drug discovery is still a lengthy, " expensive, difficult, and inefficient process " with low rate of new therapeutic discovery.

Despite literature on Dance Therapy dating back to the 1940s, there remains no scientific evidence what so ever for the therapeutic efficacy of DMT.

Despite these features which make MBDB less desirable as a recreational drug, it has been suggested that the drug may have greater therapeutic potential than MDMA.

Despite the value and importance of protecting the therapist-client relationship, the court decided that the clinician ’ s duty to society as a citizen of that society places certain limitations on the clinician ’ s loyalty to a client ’ s secrets, divulged in the context of the therapeutic relationship.

Despite pronouncements at the highest levels of government on the importance of free competition, Armenia is next to last in the effectiveness of its anti-monopoly policy according to the 2010 results of the World Economic Forum Global Competitiveness Report.

Despite there having been many versions over the years, somehow the perception of many users is that the current map actually is, more or less, Beck's original version from the 1930s — a testament to the effectiveness of his design.

Despite the effectiveness of the vaccination, outbreaks of this disease continue to occur nationally.

Despite strong evidence for the effectiveness of the jigsaw classroom, the strategy was not widely used ( arguably because of strong attitudes existing outside of the schools, which still resisted the notion that racial and ethnic minority groups are equal to Whites and, similarly, should be integrated into schools ).

Despite the effectiveness of clozapine for treatment-resistant schizophrenia, agents with a more favourable side effect profile were sought after for widespread use.

Despite their effectiveness, CCB's often have a high mortality rate over extended periods of use, and have been known to have multiple side effects.

Despite steaming side-by-side with Schley's flagship at about and even with some good shooting which knocked out a secondary gun aboard Brooklyn, almost none of the Spaniards ' nearly 300 shots caused significant damage, while Brooklyn pounded Vizcaya with effectiveness.

Despite continuous cuts and restructuring in the public sector and legislation aimed at reducing the effectiveness of unions, PSA membership continues to grow, particularly in community-based services.

Despite these events, she maintained a strong outlook on life, helping to maintain discipline, reduce tension, and increase the team's effectiveness throughout Europe.

Despite their effectiveness, non-water agents do not cleanse the hands of organic material, but simply disinfect them.

Despite the effectiveness of yorkers, they are notoriously difficult to bowl correctly and will usually be attempted only a handful of times during a sequence of several overs.

Despite the technical developments, chemical weapons suffered from diminishing effectiveness as the war progressed because of the protective equipment and training which the use engendered on both sides.

Despite being sometimes contested, the format remains popular due to its utility, reliability, and cost effectiveness.

Despite their effectiveness, the sable's horns have contributed to the sharp decline of the animal, being a highly prized hunting trophy.

Despite the rain and the soft ground which reduced the effect of the shell bursts, the effectiveness of the artillery was aided by the otherwise favourable technical conditions which prevailed, including the location of the infantry between the guns and the assaulting Viet Cong, the convenient range of at which the engagement occurred, good communications afforded by the newly issued PRC-25 radios, the airburst affect created by rounds exploding in the rubber trees, and a large supply of rounds which had been stock-piled at Nui Dat.

Despite being a high priority target, Fireflies appear to have had a statistically lower chance of being knocked out than standard Shermans ; this was probably due more to how they were employed than to the actual effectiveness of the attempted camouflaging of the long barrel.

Despite its proven effectiveness, some officers, notably Captain Kenneth Adams, RCN, opposed fitting Squid to escorts because it meant sacrificing guns, which would make ships unsuitable for fleet actions.

Despite the volume of work carried out, controversy continues today concerning the procedure's effectiveness.

Despite the fact that the international community addressed the effectiveness issue through the Paris Declaration and the subsequent Accra Agenda for Action, the implementation of this agenda has been difficult.

Despite his arm not being fully healed and his slider's reduced effectiveness, he still managed to save an impressive 32 games for the Jays, good enough to place 6th on the AL list of top saves by closers.

Summarizing a 2011 national survey of more than 5, 300 middle school and high school counselors, researchers argued: " Despite the aspirations of counselors to effectively help students succeed in school and fulfill their dreams, the mission and roles of counselors in the education system must be more clearly defined ; schools must create measures of accountability to track their effectiveness ; and policymakers and key stakeholders must integrate counselors into reform efforts to maximize their impact in schools across America ".

Despite the success and effectiveness of ORT, its uptake has recently slowed and even reversed in some developing countries.

Despite their effectiveness, there are noteworthy challenges related with mobile ANPRs.

Despite the fact that it has not been formally proven, the Church – Turing thesis now has near-universal acceptance.

Despite some allegations that EMR exposure has negative health consequences, at this time, no link has been verifiably proven between the radio-frequency EMR that tin foil hats are meant to protect against and subsequent ill health.

Despite its inherent association with extremely flammable substances and objects with a pointed tip traveling at high speeds, model rocketry historically has proven to be a very safe hobby and has been credited as a significant source of inspiration for children who eventually become scientists and engineers.

Despite Louie sometimes fails to understand people's aims, he has proven to be a rational thinker ; when the trio come up with a plan for a particular situation Louie is usually the first of the boys to have second thoughts and rethink the plan and compare it to the situation.

Despite an investment of A $ 600 million developing the car, initial sales projections have so far proven optimistic ; after only six months Mitsubishi scaled back production from 90 / day, and reduced the working week from five days to four.

Despite the Stars ' demise, Salt Lake City had proven it could support big-time professional basketball.

Despite his low status and general disrespect by his peers, Coconuts has proven that he is much smarter than Scratch and Grounder, often being the only one to see through Sonic's disguises.

Despite some arguable theories ( for instance, the Book of Veles ), it has not been proven that the Slavs had any sort of writing system before the arrival of Saints Cyril and Methodius to Slavic lands in 862.

Despite the fact that the scroll is proven to be authentic, most Klingons still see their Emperor as a semi-divine figure.

Despite this, Tecún Umán's existence is not well documented, and it has proven to be difficult to separate the man from the legend.

Despite its age, the Open Inventor API is still widely used for a wide range of scientific and engineering visualization systems around the world, having proven itself well designed for effective development of complex 3D application software.

Despite Avro Canada's success in producing the CF-100, Canada's first jet fighter for the Royal Canadian Air Force ( RCAF ), aircraft development had proven to be a time-consuming and expensive process.

Despite the proven armour-penetration capability of firearms, they were also very inaccurate, slow-loading, and susceptible to damp conditions, and did not fit well with the fast-paced attack tactics used by the Swiss mercenary pike forces.

Despite the infrequency of these plays, some receivers have proven to be capable passers, particularly those with prior experience as a quarterback.

Despite these limitaitons, MUF has proven to be a very successful and appropriate tool for its intended purposes.

Despite the increased ease of use of PLM tools, cross-training all personnel on the entire PLM tool-set has not proven to be practical.

Despite being named for Ferdinand Georg Frobenius, the theorem was first proven by Alfred Clebsch and Feodor Deahna.

Despite their reduction, light forces have proven successful in Afghanistan ( Operation Enduring Freedom ), underlining the continued need for light infantry.

Despite great demand, many such products and treatments have not been proven to give lasting or major positive effects.

Despite this, it is unlikely that the British East India Company would have deliberately attempted to annex the Punjab had the war not occurred, as they simply did not have the manpower or resources to keep a hold on the territories ( as proven by the outbreak of the Second Anglo-Sikh War ).

Despite efforts from everybody she knows to convince her otherwise, her love for Ataru remains unchanged because he has consistently proven that he genuinely cares for her well-being in spite of his idiotic facade.

Despite being initially written for a single computer architecture, Open64 has proven that it can generate efficient code for CISC, RISC, and VLIW architectures, including MIPS, x86, IA-64, ARM, and others.

Despite his controversial history, Abu Bakr has proven to be a survivor in Trinidadian politics.