During the Fifth cholera pandemic in 1891 he ordered the construction of a hospice inside the Vatican.

During infection, V. cholerae secretes cholera toxin, a protein that causes profuse, watery diarrhea.

During the California Gold Rush, emigrants brought in cholera.

During the construction an epidemic of cholera broke out and dozens of men were buried along the banks of the canal and the Delaware River.

During these years Della Chiesa helped negotiate the resolution of a dispute between Germany and Spain over the Caroline Islands as well as organising relief during a cholera epidemic.

During the cholera outbreak in 1831, he did not hesitate to take real risks in visiting the sickest cases in the Hôtel-Dieu de Paris, accompanied by Casimir Perier ( who caught the disease and died ).

During his various tenures of office, Franscini was frequently sent on extraordinary missions, such as relief and calming missions in the Mendrisiotto during a cholera epidemic in 1836, and again during the famine of 1847.

During the 18th century Komárom experienced many natural disasters including floods, fires, earthquakes, and cholera and plague epidemics.

During the 1840s and 1850s, hundreds died each year in Philadelphia and the surrounding districts from diseases such as malaria, smallpox, tuberculosis, and cholera, related to poor sanitation and diseases brought by immigrants ; the poor suffered the most fatalities.

During the early 19th century the River Thames was an open sewer, with disastrous consequences for public health in London, including cholera epidemics.

During the cholera epidemic of 1831-32, she was interested in the relief of the sufferers.

During colonial rule an estimated 23 million people died from cholera between 1865 and 1949, and millions more died from plague, malaria, influenza and tuberculosis.

During 2004 and 2005, there was an outbreak of cholera, with eight people recorded to have suffered the disease.

During this journey, Whitman treated several fur trappers during an outbreak of cholera.

During the Hamburg cholera epidemic of 1892 he was detailed for duty with the New York quarantine station as a consultant on disinfection as applied to ships, their personnel, and cargo.

During the early years of settlement, the river acted as both the city ’ s primary water source and main sewer, leading to outbreaks of typhus and cholera.

During the Sacramento Cholera Epidemic of October 1850, Bigler contracted cholera as a direct result of his remaining in the city and assisting doctors and undertakers.

During a cholera epidemic he stayed in Buda in 1831.

During 1867, when Alice was 15 years old, a cholera epidemic broke out among the Seminole tribe, and she assisted her father in caring for the sick.

During the national cholera epidemic in 1833, Delany became apprenticed to Dr. Andrew N. McDowell, where he learned contemporary techniques of fire cupping and leeching, then considered the primary techniques to treat disease.

During another cholera outbreak in 1854, most doctors abandoned the city, as did many residents who could leave, as no one knew how the disease was caused nor how to control the epidemic.

During the Black Hawk War of 1832, General Winfield Scott's troops brought cholera with them from the East Coast, where an epidemic raged.

During the Crimean War an Ottoman garrison led by British officers including General William Fenwick Williams kept the Russians at bay during a protracted siege ; but after the garrison had been devastated by cholera and food supplies had depleted, the town was surrendered to General Mouravieff in November 1855.

During his apprenticeship, he aided his uncle in treating victims of cholera outbreaks in Lexington and Paris.

Within a short while, he grasps what is at stake and warns the authorities that unless steps are taken immediately, the epidemic could kill off half the town's population of two hundred thousand within a couple of months .</ br > During the epidemic, Rieux heads an auxiliary hospital and works long hours treating the victims.

During the negotiations Himmler falsely claimed that the crematoria had been built to deal with the dead from a typhus epidemic.

During the nineteenth century, due to the absence of drainage systems and the weak economy of the region, the excess water of this area flooded many acres of the land in the vicinity of residential areas causing a malaria epidemic in the region.

During the return trip to Germany an epidemic broke out among the troops.

During the second year of the Peloponnesian War ( 430 BC ), the city-state of Athens in ancient Greece was hit by a devastating epidemic, known as the Plague of Athens, which killed, among others, Pericles and his two elder sons.

During World War II he had been responsible at the German Supreme High Command institute for virus and typhus research in Kraków to produce Rudolf Weigl's vaccine against epidemic typhus.

During this period, an epidemic of feline leukemia virus occurred, and many wild cats apparently had a natural immunity to the disease.

During the 1918 influenza epidemic, an African-American nurse ( Viola Pettus ) living in the border area of Brewster County became legendary for her courageous and selfless treatment of anyone with the disease – including raiders and refugees from Mexico, and local members of the Ku Klux Klan.

During the flu epidemic, the local undertaker left town in the middle of the night taking the cemetery records with him.

During 2005, the largest recorded epidemic of diarrhoea occurred in Nicaragua.

During the smallpox epidemic of 1711, which killed Louis, le Grand Dauphin and three siblings of the future Holy Roman Emperor Francis I, Joseph became infected.

During the 10th and the 11th centuries, the city strengthened its link with the papal court: In fact, the popes began to consider the old capital city of the Hernici a safer and healthier spot compared to Rome, which was the place of frequent epidemic diseases.

During the epidemic in the US between 1962 – 1965, Rubella virus infections during pregnancy were estimated to have caused 30, 000 still births and 20, 000 children to be born impaired or disabled as a result of CRS.

During the epidemic, there were only a small number of men who remained healthy and bore the responsibility of caring for the sick.

During his presidency, George Washington and his family lodged at the Deshler-Morris House in Germantown to escape the city and the yellow fever epidemic of 1793.

During the late 1970s, ethchlorvynol was sometimes over-prescribed causing a minor epidemic of persons who became addicted to this powerful drug.

During the fall of 1862 an epidemic of measles and typhoid fever ran rampant through the troops congregated there.

During the expansion of the American and Canadian West, boosterism became epidemic as the leaders and owners of small towns made extravagant predictions for their settlement, in the hope of attracting more residents and, not coincidentally, inflating the prices of local real estate.

During the second year of the Peloponnesian War, the city-state of Athens was hit by a devastating epidemic, known as the Plague of Athens, which killed, among others, Pericles and his two elder sons.

During a diphtheria epidemic, both Easter and Jane come down with the disease.

During the Great Plague of 1665 the area of Derby, England fell victim to the bubonic plague epidemic, with many deaths.