Early stages of malignancy that are thus limited to the epithelial layer by the basement membrane are called carcinoma in situ.

Early 3270s offered three types of keyboards.

Early analog synthesizers were usually monophonic ( capable of playing only one note at a time ), and controlled via a voltage produced by their keyboards.

Early during his on-stage career, Wilson primarily played bass on stage, but gradually transitioned to primarily playing piano / keyboards.

* Apple Macintosh: Early Mac OS supported system extensions known generally as FKEYS which could be installed in the System file and could be accessed with a Command-Shift -( number ) keystroke combination ( Command-Shift-3 was the screen capture function included with the system, and was installed as an FKEY ); however, early Macintosh keyboards did not support numbered function keys in the normal sense.

Rafting by ice of stones into marine environments occurred during much of the Cretaceous but evidence of deposition directly from glaciers is limited to the Early Cretaceous of the Eromanga Basin in southern Australia.

Early food processing techniques were limited by available food preservation, packaging, and transportation.

Early fighters were very small and lightly armed by later standards, and most were biplanes built with a wooden frame, covered with fabric, and limited to about 100 mph.

Early ICBMs had limited accuracy that allowed them to be used only against the largest targets such as cities.

Early encodings were limited to 7 bits because of restrictions of some data transmission protocols, and partially for historical reasons.

Early MUMPS memory partitions were limited to 2048 bytes so aggressive abbreviation greatly aided multi-programming on severely resource limited hardware, because more than one MUMPS job could fit into the very small memories extant in hardware at the time.

Early operating system kernels were rather small, partly because computer memory was limited.

Early Neolithic farming was limited to a narrow range of plants, both wild and domesticated, which included einkorn wheat, millet and spelt, and the keeping of dogs, sheep and goats.

Early on in the history of British television, agreements with the actors ' union Equity and other trade bodies limited the number of times a single program could be broadcast, usually only twice, and these showings were limited to within a set time period such as five years.

* Trumpet: Early trumpets had no valves, and were limited to the tones present in the overtone series.

Early iron blades have rounded points due to the limited metallurgy of the time.

So far evidence for the earliest periods of the Early Bronze Age in Mesopotamia is very limited. Mesh-Ane-pada is the first king mentioned in the Sumerian King List, and appears to have lived in the 26th century BC.

Early individual experimental radio stations in the United States began limited operations in the 1910s.

Early modern exploration of the oceans was primarily for cartography and mainly limited to its surfaces and of the creatures that fishermen brought up in nets, though depth soundings by lead line were taken.

Early progress was limited, and it was not until the early 20th century that conclusive detections of astronomical objects other than the Sun and Moon were detected in infrared light.

Early public displays were mainly limited to the wearing of certain fashion items, such as collars and cuffs.

Early settlers discovered that the amount of useful agricultural land was limited as was the waterpower potential in the town.

Early serfdom in Poland was mostly limited on the royal territories ( królewszczyzny ).

Early cannons had only a limited range, were unreliable and in addition early stone cannon balls were relatively ineffective when fired at against stone castle walls.

Early enthusiasts could often get by with limited patching, but the repair requirements have slowly risen, although even to this day it is possible to find original 1920s ' instruments that still work after a fashion — a tribute to their quality, and an indication of their continued popularity.

Early speech recognition systems were DSP technology based, and were limited to small vocabularies.

Early machines were crude, used a lot of battery power, and worked only to a very limited degree.

The relative scarcity of fossil evidence prevents precise dating, but the most recent molecular study, based on multilocus sequence typing, suggest a Late Carboniferous – Early Permian origin of extant amphibians.

Early dirigible developments included machine-powered propulsion ( Henri Giffard, 1852 ), rigid frames ( David Schwarz, 1896 ), and improved speed and maneuverability ( Alberto Santos-Dumont, 1901 )

Early MUMPS programmers would often store a structure of related information as a delimited string, parsing it after it was read in ; this saved disk access time and offered considerable speed advantages on some hardware.

Early hard disks were expensive and notoriously unreliable ; if available and working, they were used primarily for speed of swapping, and not for permanent file storage.

Early assays such as the HLA-DQ alpha reverse dot blot strips grew to be very popular due to their ease of use, and the speed with which a result could be obtained.

Early dirigible developments included machine-powered propulsion ( Henri Giffard, 1852 ), rigid frames ( David Schwarz, 1896 ), and improved speed and maneuverability ( Alberto Santos-Dumont, 1901 )

Early tanks were not weapons of mobile warfare — with a top speed of, they were easily outpaced by the infantry — but were designed for trench warfare.

Early in 1952, a high-speed shifter was added, which improved the speed for shifting by a factor of five.

Early drivers were buggy and slow, while 3dfx cards enjoyed efficient, high speed, mature Glide API and / or MiniGL support for the majority of games.

Early speed metal bands include Running Wild, Grave Digger, Rage, and to some extent Accept & Warlock.

Early generation Zip drives were in direct competition with the SuperDisk or LS-120 drives, which held 20 % more data and could also read standard 3½ " 1. 44 MB diskettes, but they had a lower data transfer rate due to lower rotational speed.

Early sawmills simply adapted the whipsaw to mechanical power, generally driven by a water wheel to speed up the process.

Early cars used AC's elderly two-litre overhead cam straight-six engine ( first seen soon after the end of the First World War ), which, according to a 1954 road test by Motor magazine, gave a top speed of and in 11. 4 seconds and a fuel consumption of.

Early steam engines employed a purely reciprocating motion, and were used for pumping water – an application that could tolerate variations in the working speed.

Early S & C allowed only a very slow speed on the subsidiary route ( the " turnout "), so geometrical design was not too important.

Early 1999 marked the release of their latest video codec, Bink Video, which provided better than DVD quality compression in true color at up to three times the playback speed.

Early glass cockpits, found in the McDonnell Douglas MD-80 / 90, Boeing 737 Classic, 757 and 767-200 /- 300, and in the Airbus A300-600 and A310, used Electronic Flight Instrument Systems ( EFIS ) to display attitude and navigational information only, with traditional mechanical gauges retained for airspeed, altitude and vertical speed.

Early diagnosis of the disorder can diminish familial stress, speed up referral to special educational programs and influence family planning.

Early Marders could achieve a road speed of 75 km / h in 4th gear, but the extra armour of later vehicles reduced this to 65 km / h.

Early fire control consisted of range measurements and calculation of the submarines course and speed.

Early in the morning of 15 August, Viktor Tsoi was driving on the road Sloka-Talsi from a fishing trip when his Aleko collided with a bus outside Tukums at high speed.

Early designs like the SPARC and MIPS often ran over 10 times as fast as Intel and Motorola CISC solutions at the same clock speed and price.

Early researches by Friedrich Wilhelm Bessel ( 1784 – 1846 ) in Königsberg and Adolf Hirsch led to the development of a highly precise chronoscope by Mathias Hipp that, in turn, was based on a design by Charles Wheatstone for a device that measured the speed of artillery shells ( Edgell & Symes, 1906 ).

Early engines were designed for simplicity, and used a single large compressor spinning at a single speed.

Early in his career, Colón had excellent speed on his four-seam fastball, throwing it in the mid 90s and occasionally touching 100 mph.