On December 2, 1942, physicist Enrico Fermi conducted the world's first controlled nuclear reaction at the University of Chicago as part of the top-secret Manhattan Project.

In 1939, with Enrico Fermi, Szilárd proved this neutron-multiplying reaction in uranium.

Demonstration of a self-sustaining nuclear chain reaction was accomplished by Enrico Fermi and others, in the successful operation of Chicago Pile-1, the first artificial nuclear reactor, in late 1942.

* 1942 – Manhattan Project: A team led by Enrico Fermi initiates the first self-sustaining nuclear chain reaction.

More recent campaigning by anti-nuclear groups has related to several nuclear power plants including the Enrico Fermi Nuclear Power Plant, Indian Point Energy Center, Oyster Creek Nuclear Generating Station, Pilgrim Nuclear Generating Station, Salem Nuclear Power Plant, and Vermont Yankee Nuclear Power Plant.

Enrico Fermi (; 29 September 1901 – 28 November 1954 ) was an Italian physicist, naturalized American later in his life, particularly known for his work on the development of the first nuclear reactor, Chicago Pile-1, and for his contributions to the development of quantum theory, nuclear and particle physics, and statistical mechanics.

Several awards, concepts, and institutions are named after Fermi, such as the Enrico Fermi Award, the Enrico Fermi Institute, the Fermi National Accelerator Laboratory, the Fermi Gamma-ray Space Telescope, the Enrico Fermi Nuclear Generating Station, a class of particles called fermions, the synthetic element fermium, and many more.

Evenings, he was frequently to be seen at restaurants like Enrico & Paglieri's or Peter's Backyard drunkenly donning ladies' hats and singing `` O Sole Mio ''.

Initially named " Digital European Cordless Telephone " at its launch by CEPT in November 1987, following a suggestion by Enrico Tosato of Italy, its name was soon changed to " Digital European Cordless Telecommunications " to reflect its broader range of application, including data services.

When Giulio died unexpectedly of a throat abscess in 1915, Enrico was distraught, and immersed himself in scientific study to distract himself.

In 1923, while writing the appendix for the Italian edition of the book The Mathematical Theory of Relativity by A. Kopff, Enrico Fermi pointed out, for the first time, that hidden inside the famous Einstein equation (), there was an enormous amount of nuclear potential energy to be exploited.

On 25 January 1939, a Columbia University team conducted the first nuclear fission experiment in the United States, which was done in the basement of Pupin Hall ; the members of the team were Herbert L. Anderson, Eugene T. Booth, John R. Dunning, Enrico Fermi, G. Norris Glasoe, and Francis G. Slack.

It was discovered in the debris of the first hydrogen bomb explosion in 1952, and named after Nobel laureate Enrico Fermi, one of the pioneers of nuclear physics.

The element was named after Enrico Fermi.

In 1993, Dyson was given the Enrico Fermi Award.

Fiorello Henry LaGuardia (; born Fiorello Enrico La Guardia ; December 11, 1882September 20, 1947 ) was Mayor of New York for three terms from 1934 to 1945 as a Republican.

His middle name “ Enrico ” was changed to “ Henry ” ( the English form of Enrico ) when he was a child.

The equation was formulated by Dr. Frank Drake in 1961, a decade after the objections raised by Enrico Fermi, in an attempt to find a systematic means to evaluate the numerous probabilities involved in alien life.

Hayek's first class at Chicago was a faculty seminar on the philosophy of science attended by many of the University's most notable scientists of the time, including Enrico Fermi, Sewall Wright and Leó Szilárd.

He was the cousin of Enrico Berlinguer.

According to Italian journalist Enrico Deaglio, Cossiga to justify his lack of action " accused the leaders of CGIL and of the Italian Communist Party to know the location where Moro was detained ".

This was commissioned by, and first performed at, the Metropolitan Opera in New York on 10 December 1910 with Met stars Enrico Caruso and Emmy Destinn for whom Puccini created the leading roles of Dick Johnson and Minnie.

Enrico Arrigoni ( pseudonym: Frank Brand ) was an Italian American individualist anarchist Lathe operator, house painter, bricklayer, dramatist and political activist influenced by the work of Max Stirner.

Founded in 1897 as Sport Club Juventus by a group of young Torinese students, among them, who was their first president, Eugenio Canfari, and his brother Enrico, author of the company's historical memory ; they are managed by the industrial Agnelli family since 1923, which constitutes the oldest sporting partnership in Italy, thus making Juventus the first professional club in the country.

He was the father of Giovanni and Enrico Berlinguer, outstanding members of the Italian Communist Party.

After nuclear fission was discovered by others in 1938, Szilárd and Enrico Fermi in 1939 searched for, and discovered, neutron multiplication in uranium, proving that a nuclear chain reaction by this mechanism was indeed possible.

Enrico Bombieri ( born 26 November 1940 in Milan, Italy ) is a mathematician who has been working at the Institute for Advanced Study in Princeton, New Jersey.

* August 2 – Enrico Caruso, Italian tenor ( born 1873 )

Notable people born here include the former presidents of the Italian Republic, Antonio Segni and Francesco Cossiga, and Enrico Berlinguer, secretary of the Italian Communist Party.

The son of Mario Berlinguer and Maria Loriga, Enrico Berlinguer was born in Sassari, Italy to a noble and important Sardinian family, in a notable cultural context, with family ties and political contacts that would heavily influence his life and career.

Enrico Mattei was born in Acqualagna, in the province of Pesaro and Urbino, Marche, as the second of five children of Antonio Mattei ( a carabiniere ( a member of the Italian national gendarmerie ) and Angela Galvani.

Enrico De Nicola was born in Naples and became famous as one of the most esteemed penal lawyers in Italy.

It was directed from July 1935 to May 1963 by the Italian Henri Théodore Pigozzi ( born Enrico Teodoro Pigozzi, 1898 – 1964 ).

Henri Théodore Pigozzi ( born Teodoro Enrico Pigozzi ) was active in the automotive business in the early 1920s when he met Fiat founder, Giovanni Agnelli.

Its official name is Airport Enrico Forlanini, after the Italian inventor and aeronautical pioneer born in Milan.

Enrico Anthony " Rick " Lazio (; born March 13, 1958 ) is a former U. S. Representative from the state of New York.

Under scrutiny, the claims of Maria Pia ( or Hilda ) are similar to those of several Europeans born outside marriage who entertain the idea, or fantasy, of descent from royalty ; Enrico Vigo, who claims the Byzantine Crown, is another example.

* November 29 – Enrico Fermi ( born 1901 ), Italian American physicist.

Enrico Gatti ( born in 1955 in Perugia, Italy ) is a baroque violinist.

Sheila Hancock was born in Blackgang on the Isle of Wight, the daughter of Ivy Louise ( née Woodward ) and Enrico Cameron Hancock, who was a publican.

* Enrico Clementi ( born 1931 ), an Italian pioneer in computational techniques

Henri Pigozzi ( Henri Théodore Pigozzi ) ( 26 June 1898 – 18 November 1964 ), a car merchant and industrialist, was born as Enrico Teodoro Pigozzi in Turin, Italy.

Enrico was born to Francesco Forlanini, a notable physician and director of the Ospedale Fatebenefratelli in Milan.

Enrico Colantoni ( born February 14, 1963 ) is a Canadian actor, probably best known for portraying Elliot DiMauro in the sitcom Just Shoot Me !, Keith Mars on the television series Veronica Mars, and Sergeant Greg Parker on the television series Flashpoint.

* Enrico Rossi Chauvenet ( born 1984 ) Italian footballer

Armetta was born Enrico Armetta in Palermo, Sicily.

Enrico Bertaggia ( born September 19, 1964 in Noale, Venice ) is a former racing driver from Italy.

Enrico Tellini was born in Castelnuovo di Garfagnana in the province of Lucca in Tuscany.

Enrico Chiesa (; born December 29, 1970 in Genoa ) is an Italian football coach and former striker.