Firstly the outer membrane is removed as the particle enters the cell ; secondly the virus particle ( without the outer membrane ) is uncoated further to release the core into the cytoplasm.

Firstly, Pichia, as mentioned above, is a methylotroph, meaning it can grow with the simple alcohol methanol as its only source of energy — Pichia can easily be grown in cell suspension in reasonably strong methanol solutions that would kill most other micro-organisms, a system that is cheap to set up and maintain.

Firstly, cyberspace describes the flow of digital data through the network of interconnected computers: it is at once not " real ", since one could not spatially locate it as a tangible object, and clearly " real " in its effects.

The problems other philosophers have had with Mill's position center around the following issues: Firstly, Mill's formulation encounters difficulty when it describes what direct experience is by differentiating only between actual and possible sensations.

This is for two reasons: Firstly, many ethnic Faroese live in Denmark and few who are born there return to the Faroes with their parents or as adults.

Firstly, there is metaphysical or philosophical materialism, in which matter-in-motion is considered primary and thought about matter-in-motion, or thought about abstractions, secondary.

Firstly, the " aboutness " of the material is ascertained.

Firstly, particularly in the Discourses on Livy, Machiavelli is unusual in the positive side he sometimes seems to describe in factionalism in republics.

Firstly, it is applicable only to situations in which there is only a ' finite ' number of possible outcomes.

Firstly, a few inches below a branch-trunk joint on a tree trunk where the moth is in shadow ; secondly, on the underside of branches and thirdly on foliate twigs.

Firstly, it is the extent of self-determination a people are given to protect themselves and determine how they wish to be ruled and what role is played by human rights violations, cultural eradication and pogroms by the Azerbaijani majority against the Armenian communities of Azerbaijan in a decision.

Firstly, the urge to transcend one ’ s self is universal through times and cultures ( and was characterized by H. G.

Firstly, XMI 2. x is large and complex in its own right, since it purports to address a technical problem more ambitious than exchanging UML 2. x models.

Firstly, as there is no authentication, an attacker can edit a message and recompute the CRC without the substitution being detected.

Firstly, the file system is not a single tree, but instead is a forest with each tree corresponding to a device.

Firstly, the spreading out of electromagnetic energy in free space is determined by the inverse square law, i. e.

Firstly there was the Aristotelian view that there simply was no void and that everything that exists objectively is in the category of substance.

Firstly, the mathematical and geometrical nature of the construction is an image of the orderly universe, in which an underlying rationality and logic can be perceived.

Firstly, the accepted mathematical structure of quantum mechanics is based on fairly abstract mathematics, such as Hilbert spaces and operators on those spaces.

Firstly, the use of such a weapon is of no use to an occupying force, as the target area becomes uninhabitable ( due to the fallout caused by radioactive poisoning of the involved environment ).

Firstly, property 1 ensures W is nonempty.

Firstly there was a cover of David Bowie's 1972 glam-rock classic " Suffragette City ", slightly renamed to " SufferRAGEette City " to fit in with the " Rage Hard " promotion.

Firstly, it recognizes that any object or situation can be rendered hazardous by the involvement of someone with an inappropriate disposition towards risk ; whether too risk taking or too risk averse.

Firstly, the containers were rather small, with 52 % of them having a volume of less than.

Firstly, contemporary works, including concertos and sonatas, usually specifically written for Segovia himself by composers he forged working relationships with, notably Spaniards such as Federico Moreno Torroba, Federico Mompou, and Joaquín Rodrigo, the Mexican composer Manuel Ponce, the Italian composer Mario Castelnuovo-Tedesco, and the great Brazilian composer Heitor Villa-Lobos.

Firstly, the Great St. Albans Chase, which had clashed with the steeplechase at Aintree, was not renewed after 1838, leaving a major hole in the chasing calendar.

Firstly, he took the best troops in the army, and arranged them 50 ranks deep ( as opposed to the normal 8 – 12 ranks ) on the left wing, opposite Cleombrotus and the Spartans, with Pelopidas and the Sacred Band on the extreme left flank.

Firstly, a former High Master of St Paul's School, Richard Mulcaster is credited with taking mob football and turning it into an organised, refereed team sport that was considered beneficial for schoolboys.

Firstly, suppose with.

Firstly he was the first Australian overall commander of Australian forces and took, as subsequent Australian commanders did, a relatively independent line with his British superiors.

Firstly, the ideology entails built-in tensions and frequently requires conscious living with inconsistency ( even in the term itself: modernity vs. orthodoxy ).

Firstly, the northeast lowlands of Java were suitable for rice cultivation, and during Majapahit's prime numerous irrigation projects were undertaken, some with government assistance.

Firstly, Hillel ben Samuel's importance in the history of medieval Jewish philosophy lies in his attempt to deal, systematically, with the question of the immortality of the soul.

Firstly, the European Union passed Directive 91 / 440, which prescribed, among other things, the ( formal ) separation of the national railways into two separate companies, one which deals with the infrastructure, and the other which deals with the transport activities.

Firstly, an institution with an entrepreneurial philosophy will set entrepreneurial goals and strategies as a whole, but maybe even more importantly, it will foster an entrepreneurial milieu, allowing each entity to pursue emergent opportunities.

Firstly, large numbers of connections ( for example, those with peer-to-peer ( P2P ) software ) would cause the connection to slow down and eventually freeze the modem part of the STB ( also required for interactive TV services, which suffered a similar effect when downloading ).

Firstly, it's not to be confused with today's surgically enhanced Hollywood porn starlets or even slim, naturally endowed actresses.

Firstly, IBM chose to stick to the hierarchical model with semi-network extensions in their established products such as IMS and DL / I.

Firstly there were the canal owners with which it was being built to compete.

Firstly the Jomar MK2, a sports racing car, with either fibreglass or aluminum bodywork and 1, 098 c. c.

Firstly, unlike preceding classes, the " maximum battleships " were designed with a continuous flush main deck.