From the neolithic age Asia Minor was the route of the forward-Asiatic cultural stream which moved from the Near East to the west and spread the agriculture to the east coasts of Greece and Crete during the 5th millennium BC and then to the Balkan region and the whole of Europe.

From the Black Sea, trade could continue to Asia along the Silk Road, another ancient trade route.

From Elmers End to Woodside route 1 and route 4 ( and route 2 from Arena ) follow the former British Rail branch line to Addiscombe, then diverge to reach Addiscombe tram stop, which is 500 metres west of the now-demolished Addiscombe railway station.

From Woodside to near Sandilands ( routes 1, 2 and 4 ) and from near Sandilands almost to Lloyd Park ( route 3 ) Tramlink follows the former Woodside and South Croydon Railway, including the Park Hill ( or Sandilands ) tunnels.

From Haparanda on the Finnish border, it stretches south along the Gulf of Bothnia to Gävle, then on a more inland route southwards.

From Sinope he took a sea route to Crimea, arriving so in the Golden Horde realm.

From about 1500, Portuguese trading posts and forts became regular ports of call on the new route to the east.

From the roundabout are four exits ; one to the high street, one to Kingston upon Thames, and two others which go to the main A3 London to Portsmouth Road which has been the main route from the south of England docks to Central London for several hundred years.

From 1930 to 1931 the US Army Corp of Engineers survey team of 300 men, surveyed the route of any future canal, called the Forty-Niners route because it followed closely the route that miners took in the 1840s California Gold Rush.

From Huancayo the route is extended by the Ferrocarril Huancayo-Huancavelica.

From there the communications traffic was routed to the US border by a microwave radio relay link, and in Brunswick, Maine the route joined the main US network and branched to Montreal to connect with the Canadian network.

From there, she probably took a common route for fleeing slaves-northeast along the Choptank River, through Delaware and then north into Pennsylvania.

From the headwaters of the Rio Grande Wolf Creek Pass is the route of U. S. Highway 160 between Del Norte, Colorado and Pagosa Springs, Colorado, while Slumgullion Pass is the route of State Highway 149 between U. S. Highway 160 and Lake City, Colorado.

From San Luis, the National Geographic road trip suggests traveling west on Colorado State Highway 142 through Manassa, Colorado, then south on United States Highway 285 past Conejos, Colorado then west on Colorado State Highway 17 over Cumbres Pass to Chama, New Mexico paralleling the route of the narrow gauge Cumbres & Toltec Scenic Railroad.

From 28 August 2011, irregular route numbers started changing, aiming to simplify the numbering system, thus avoiding passenger confusion.

From Norton to Foxton, the route is a narrow canal.

From Leicester to the Trent, the route is effectively the River Soar and the locks and bridges are wide.

From then until the 18th century the town remained a small settlement on a trade route between Masovia and Silesia.

From about 1500, Portuguese trading posts and forts became regular ports of call on the new route to the east.

From here he took the land route to Yokohama, visiting along the way the three big cities of Osaka, Kyoto and Tokyo.

From the northern shore of Manhattan, Broadway crosses Spuyten Duyvil Creek via the Broadway Bridge and continues through Marble Hill ( a discontinuous portion of the borough of Manhattan ) and the Bronx into Westchester County.

From its headwater, the Apure crosses the llanos in a generally eastward direction.

From Truro, the highway continues east for to New Glasgow ( where it links with provincial Highway 106 — that portion of the Trans-Canada running to the ferry terminal at Caribou ), and then northeast for another to the Canso Causeway which crosses the Strait of Canso to Cape Breton Island near Port Hawkesbury.

From the 19th century, many large modern versions have been erected for various functions, and smaller Celtic crosses have become popular for individual grave monuments, usually featuring only abstract ornament, usually interlace.

From Vindolanda the Stanegate crosses the route of the present-day Military Road and passes just south of the minor fort of Haltwhistle Burn.

From Brampton Old Church, the road crosses the River Irthing and continues east through Irthington and High Crosby.

From the Ohio border just north of Toledo, it proceeds northerly via Monroe, Detroit, Flint, Saginaw and Grayling, crosses the Mackinac Bridge after passing through the village and continues on to the Upper Peninsula and Sault Ste.

From just before Newbridge, where the modern A614 road crosses the waterway, this branch of the navigation runs parallel to the Dutch River, an artificial channel built in 1635 to alleviate flooding caused by Cornelius Vermuyden's original diversion of the River Don northwards to the River Aire in 1628.

From here, the Adelson Ferry, a vehicular cable ferry crosses to Adelsö.

From here, the route turns northwest and crosses County Route 543 before heading through a mix of farm fields and suburban residential neighborhoods.

From north to south, the Appalachian Basin Province crosses New York, Pennsylvania, eastern Ohio, West Virginia, western Maryland, eastern Kentucky, western Virginia, eastern Tennessee, northwestern Georgia, and northeastern Alabama.

From this interchange, the road continues north-northeast and crosses Newton Creek into Haddon Township.

From the roundabout with the A461 ( for Dudley ) at Great Bridge, it overlaps the A461 ( to Walsall ), crosses the Tame Valley Canal, meets the A4037 at a roundabout and goes under the Midland Metro near Wednesbury Parkway station.

From Junction 4 it runs across the northern suburbs of Farnborough it enters a more rural setting, crosses the South Western Railway Main Line, and passes close to the Basingstoke Canal before reaching the outskirts of Basingstoke.

From northwest to southeast, Massachusetts Route 97 also crosses through town.

From there, Route 140 crosses to the north of another truck stop and intersects with County Route 551 ( South Pennsville-Auburn Road ).

From the monument it descends steeply to the valley of the River Calder, which it crosses about 1. 6 km ( 1 mi ) west of the town of Hebden Bridge, the largest settlement near the route.

From Lothersdale the trail crosses Pinhaw Beacon to Thornton-in-Craven.

From Keld the path crosses the route of the Coast to Coast Walk, then ascends a side valley known as Stones Dale to reach Tan Hill and its isolated inn at the northern boundary of the National Park.

From Baldersdale the trail crosses Lunedale and descends to the small town of Middleton-in-Teesdale.

From the village of Adwick upon Dearne, which is a little further to the south, Harlington Road crosses the river at Adwick Bridge, a grade II listed twin-arched bridge built of sandstone around 1800.

From launch until 1985, both the Burrard Otter and the Burrard Beaver were painted a bright orange colour — the idea being to make them highly visible to other ships / tugs using the harbour since its route crosses the path of other traffic.

From there, it passes through Dunstable, where it crosses and briefly multiplexes with the A505.

From just north of Milton Keynes, the road resumes as a single carriageway that continues through Towcester where it crosses the A43 dual carriageway just north of the town.

From this junction it proceeds south to the west of Bebington through junction 4 and then further south for ( where it crosses the Wirral railway line ), before narrowing to dual 2 lanes and turning sharply to the east.