Further investigation showed that this had metastasised to her left kidney and bones, including her spine and left ribs.

Further heart troubles, angina and a broken hip led to the kidney trouble which caused her to retire from acting in 1997.

Further compaction leads to transcriptionally inactive heterochromatin.

Further, selection arises because different types of sequences tend to replicate at different rates, which leads to the suppression of sequences that replicate more slowly in favor of sequences that replicate faster.

Further scarring from acid damage to the lower esophagus many times leads to the development of fibrotic narrowing, also known as strictures which can be treated by dilatation, and Barrett's esophagus.

Further description leads the two spacemen to believe that this man is Jesus ( though he is never named, leaving room for other religious personas ).

Further studies. showed that this model when combined with a lumbar spinal cord myelotomy leads to the hindbrain herniation characteristic of the Chiari II malformation and that in utero surgery restores normal hindbrain anatomy by stopping the leak of cerebrospinal fluid through the myelomeningocele lesion.

Further investigation leads to Sir August who is now trying to blackmail the world's leaders with his control of the weather, but Steed and Mrs. Peel defeat him on his secret island.

Further, stimulation of beta-adrenergic receptors leads to glycogenolysis and gluconeogenesis and thus elevation of blood glucose levels ).

Further, an activation of the coagulation cascade leads to microthrombi formation and aggravates the perfusion problem.

Further investigation leads the crew to Earth, the homeworld of the Old Empire.

Further trekking leads along a major secondary valley to the Larkha La.

Further lipid evolution leads to self-supporting lipid membranes and closed cells.

Further work on the information from the trucking company leads IFOR to a Sarajevo address.

Further increasing the phosphorus content leads to formation of a very hard compound Cu < sub > 3 </ sub > P ( copper phosphide ), resulting in a brittle form of phosphor bronze, which has a narrow range of applications.

Further south a valley and jeep track leads west towards the Wakhjir Pass to the Wakhan Corridor.

Further casting sessions for secondary leads and ensemble were set for September 2001.

Further automation leads to the idea of a silicon compiler.

Further investigation leads Nancy to believe Gay Moreau, an actress sent to prison by her father for forgery and larceny, may be involved in the case.

Further leads send Marked One towards the Chernobyl Nuclear Power Plant, where the Wish Granter may be located.

Further experiments with magnets attached to the backs of homing pigeons demonstrated that disruption of the bird ’ s ability to sense the Earth's magnetic field leads to a loss of proper orientation behavior under overcast conditions.

Further investigation of mole rat magnetoreception lead to the finding that exposure to magnetic fields leads to an increase in neural activity within the superior colliculus as measured by immediate early gene expression.

Further exacerbating the tensions of the day, Helene's black boyfriend Gbatokai ( Gbatokai Dakinah ) shows up, enraging the racist Michael who later leads most of the partygoers in a racist children's song to offend him.

Further information decoded from Dr. Onishi's microchip leads the Autobots to the site of a crashed Cybertronian spaceship containing six protoform Autobots.

Further cell division leads to the tadpole stage, with further elongation resulting in the first stage juvenile, which is roughly four times as long as the egg.

Further altercations between the Indians and the American settlers leads Red Cloud ( Raoul Trujillo ) to begin to gather the forces that will lead to Red Cloud's War.

Further innovations increased comfort and ushered in a second bicycle craze, the 1890s ' Golden Age of Bicycles.

Further developments in electrostatics revealed that the dielectric material was not essential, but increased the storage capability ( capacitance ) and prevented arcing between the plates.

Further, most of Paraguay's increased wealth wound up in the hands of wealthy supporters of the regime.

Further, the act increased the tariff on carpet wool, a wool of very low quality that is not produced in the US.

Further development in the following years increased the size of the city with major new developments in the Chilonzar area, north-east and south-east of the city.

Further support is provided by studies indicating that emission can be increased by addition of reactive oxygen species ( ROS ).

Further, Gay. com states that closeted individuals are reported to be at increased risk for suicide.

Further, with the increased consumption, health and education grow, also contributing to economic growth.

Further improvements included increased rates of fire ; carbon dioxide ( CO < sub > 2 </ sub >) tanks from 9 to 20 oz, and compressed air or nitrogen in sizes from 44 to 88 ci, and finally pressures up to 4500 PSI.

Further, the regimental system offers the advantage of grouping like units together for centralized administrative, training, and logistical purposes, thereby creating an “ economies of scale ” effect and its ensuing increased efficiency.

Further, Starko suggests that the wave of aspirin poisonings was due to a " perfect storm " of events: Bayer's patent on aspirin ran out, so that many companies rushed in to make a profit and greatly increased the supply ; this coincided with the flu pandemic ; and the symptoms of aspirin poisoning ( such as Reye's syndrome ) were not known at the time.

" Further, according to Wright, in the time period between the implementation of NAFTA in 1994 and the year 2001, " the homicide rate for men increased by 300 percent, while for women it increased by 600 percent.

Further, as the speed and range of land-based aircraft increased, the commercial competitiveness of flying boats diminished ; their design compromised aerodynamic efficiency and speed to accomplish the feat of waterborne takeoff and landing.

Further albums For Monkeys and compilation The Melancholy Collection followed, but the band's popularity increased in 2000 with the release of Pennybridge Pioneers, an album with more of a rock influence than the band's previous skate punk sound.

Further development of more affordable housing has increased the population of the town to approximately 28, 000 and the town remains affluent.

Further, the number of disciplines for which the award is given was increased to include indigenous games and the physically handicapped category.

Further taxonomic revision increased the number of species, by adding A. ramanantsoavana and A. betsileo.

Further, the criteria for a diagnosis of Tourette's were changed in 2000, when the impairment criteria was removed from the DSM-IV-TR for all tic disorders, resulting in increased diagnoses of milder cases.

Further ground improvements increased the official capacity of the ground to 183, 388 in 1937, but the SFA were only allowed to issue 150, 000 tickets for games.

Further, he proposed a marriage alliance, offering a dowry of £ 500, 000 ( later increased to £ 600, 000 ), which seemed especially attractive to James after the failure of the Parliament of 1614 to provide him with the financial subsidies he requested.

Further delay in changing over from left-to right-hand traffic would have greatly increased the cost burden to vehicle owners.

Further gameplay repeats the scenes with increased difficulty.

Further reforms were curtailed by the increased international tension which came to occupy most of his time.