Quinine can cause hemolysis in G6PD deficiency ( an inherited deficiency ), but this risk is small and the physician should not hesitate to use quinine in patients with G6PD deficiency when there is no alternative.

A 4-year-old boy with icteric ( jaundiced ) sclera which later proved to be a manifestation of hemolytic anemia due to G6PD deficiency following fava bean consumption.

In vivo hemolysis can be caused by a large number of medical conditions, including many Gram-positive bacteria ( e. g., Streptococcus, Enterococcus, and Staphylococcus ), some parasites ( e. g., Plasmodium ), some autoimmune disorders ( e. g., Hemolytic disease of the newborn ), and some genetic disorders ( e. g., Sickle-cell disease or G6PD deficiency ).

Hemolytic crises are a major concern with sickle-cell disease and G6PD deficiency.

Host factors associated with severe or fatal Rocky Mountain spotted fever include advanced age, male sex, African or Caribbean background, chronic alcohol abuse, and glucose-6-phosphate dehydrogenase ( G6PD ) deficiency.

Similarly, patients with Glucose-6-phosphate dehydrogenase ( G6PD ) deficiency may have impaired production of another co-factor, NADPH.

* G6PD deficiency

Gilbert's syndrome and G6PD deficiency occurring together especially increases the risk for kernicterus.

It has been reported that GS may contribute to an accelerated onset of neonatal jaundice, especially in the presence of increased hemolysis due to diseases like G6PD deficiency.

Glucose-6-phosphate dehydrogenase deficiency is an X-linked recessive hereditary disease characterised by abnormally low levels of glucose-6-phosphate dehydrogenase ( abbreviated G6PD or G6PDH ), a metabolic enzyme involved in the pentose phosphate pathway, especially important in red blood cell metabolism.

G6PD deficiency is closely linked to favism, a disorder characterized by a hemolytic reaction to consumption of broad beans, with a name derived from the Italian name of the broad bean ( fava ).

The name favism is sometimes used to refer to the enzyme deficiency as a whole, although this is misleading as not all people with G6PD deficiency will manifest a physically observable reaction to consumption of broad beans.

The World Health Organization classifies G6PD genetic variants into five classes, the first three of which are deficiency states.

Most individuals with G6PD deficiency are asymptomatic.

Abnormal red blood cell breakdown ( hemolysis ) in G6PD deficiency can manifest in a number of ways, including the following:

* Prolonged neonatal jaundice, possibly leading to kernicterus ( arguably the most serious complication of G6PD deficiency )

All individuals with favism show G6PD deficiency.

However, not all individuals with G6PD deficiency show favism.

Deficiency of G6PD is a sex-linked genetic condition affecting about 12 percent of the Afro-American male population.

Favism is known to be more prevalent in infants and children, and G6PD genetic variant can influence chemical sensitivity.

There is evidence that other antimalarials may also exacerbate G6PD deficiency, but only at higher doses.

G6PD ( Glucose-6-phosphate dehydrogenase ) human polymorphism is also implicated in malarial resistance.

This has been reported in women who are homozygous for the genetic defect causing glucose-6-phosphate dehydrogenase deficiency ( G6PD ), which is characterised by reduced NADPH levels.

This disease is worst for elderly patients, males, African-Americans, alcoholics, and patients with G6PD deficiency.

Pyruvate kinase deficiency is the second most common cause of enzyme-deficient hemolytic anemia, following G6PD deficiency.

The most dangerous adverse effect of primaquine is hemolysis in patients with G6PD deficiency ( blacks or Caucasians of Mediterranean descent ).

Eradication of the liver stages is achieved by giving primaquine, after checking the patients G6PD status to reduce the risk of haemolysis.

However, in severe G6PD deficiency, primaquine is contraindicated and should not be used.

A genetic study done on Mon and Bamar showed a high prevalence of a particular glucose-6-phosphate dehydrogenase ( G6PD ) mutation not found among Khmers, Laotians and Thais.

For example, in a small study of 757 Saudi men, more than 42 % showed a variant of G6PD deficiency, but none displayed symptoms of favism.

Other than this, the specifics of the chemical relationship between favism and G6PD are not well understood.

Many substances are potentially harmful to people with G6PD deficiency.

If the deficiency persists long enough, it is reasonable to suppose that the Af label will reflect the Af distribution in the thyroglobulin.

this is really a deficiency in the scalar field, namely, that it is not algebraically closed.

This is clearly a deficiency in T.

In West Africa, for example, where meat is a luxury and babies must be weaned early to make room at the breast for later arrivals, a childhood menace is kwashiorkor, or `` Red Johnny '', a growth-stunting protein deficiency ( signs: reddish hair, bloated belly ) that kills more than half its victims, leaves the rest prey for parasites and lingering tropical disease.

An atom containing an equal number of protons and electrons is electrically neutral, otherwise it has a positive charge if there are fewer electrons ( electron deficiency ) or negative charge if there are more electrons ( electron excess ).

"... Baeyer is an excellent experimentor, but he is only an empiricist, lacking sense and capability, and his interpretations of his experiments show particular deficiency in his familiarity with the principles of true science ..."

Chromium deficiency is controversial or is at least extremely rare.

Common competition policy is also helpful to avoid competition deficiency.

Cretinism is a condition of severely stunted physical and mental growth due to untreated congenital deficiency of thyroid hormones ( congenital hypothyroidism ) usually due to maternal hypothyroidism.

Dyslexia is distinct from reading difficulties resulting from other causes, such as a non-neurological deficiency with vision or hearing, or from poor or inadequate reading instruction.

For instance, 30 % of the world's population either has, or is at risk for developing, iodine deficiency.

It is estimated that at least 3 million children are blind due to vitamin A deficiency.

If total cash available is less than cash needs, a deficiency exists.

The Edelman algorithm works equally well for sparse and non-sparse data, since it is based on the compressibility ( rank deficiency ) of the Fourier matrix itself rather than the compressibility ( sparsity ) of the data.

Worldwide, the most common cause for goitre is iodine deficiency, usually seen in countries that do not use iodized salt.

Selenium deficiency is also considered a contributing factor.

Hemoglobin deficiency is, in general, strictly distinguished from hypoxemia, defined as decreased partial pressure of oxygen in blood, although both are causes of hypoxia ( insufficient oxygen supply to tissues ).

The major deficiency of Q1 is in the language: particularly noticeable in the opening lines of the famous " To be, or not to be " soliloquy: " To be, or not to be, aye there's the point.

Other classifications used also include: ḥasan ( good ), which refers to an otherwise ṣaḥīḥ report suffering from minor deficiency, or a weak report strengthened due to numerous other corroborating reports ; and munkar ( denounced ) which is a report that is rejected due to the presence of an unreliable transmitter contradicting another more reliable narrator.

This is a great deficiency as trade theory, for intermediate goods occupy the major part of the world international trade.