[permalink] [id link]
Genomic imprinting is an epigenetic process that involves methylation and histone modifications in order to achieve monoallelic gene expression without altering the genetic sequence.
from
Wikipedia
Some Related Sentences
Genomic and imprinting
Genomic imprinting is a genetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner.
* Genomic imprinting
* Genomic imprinting
* Genomic imprinting, an inherited repression of an allele, relying on DNA methylation
* Genomic imprinting ( genetic imprinting ), a mechanism of regulating gene expression
Genomic imprinting represents yet another example of non-Mendelian inheritance.
# REDIRECT Genomic imprinting
# REDIRECT Genomic imprinting
Genomic and is
Venter founded Celera Genomics, The Institute for Genomic Research ( TIGR ) and the J. Craig Venter Institute ( JCVI ), and is now working at JCVI to create synthetic biological organisms.
Genomic evolution is the process that changes the structure ( sequence ) or size of a genome over time.
The yellow fever mosquito ( Aedes aegypti ) genome is being sequenced by the Broad Institute and The Institute for Genomic Research ( TIGR ).
He is often featured on the Forbes Midas list and is currently on the Board of Directors of ten companies ; CardioDX, Crescendo Bioscience, Inc., Genomic Health Incorporated, Five Prime Therapeutics, OptiMedica, HX Diagnostics, Pacific Biosciences, Inc., Tethys, Veracyte, Inc. and XDx, Inc.
Genomic DNA is fragmented into random pieces and cloned as a bacterial library.
Proponents of this theory claim that 90 % of HIV RNA is found in Visna and 10 % in HTLV I. Genomic analysis, however, shows that such claims are false.
Genomic sense RNA packaged into the arenavirus virion is designated negative-sense RNA, and must first be copied into a positive-sense mRNA in order to produce viral protein.
Genomic reprogramming is the key biological process behind nuclear transfer.
The Center is establishing a Genomic Research Laboratory Core that will support the Center in its epidemiologic research.
Genomic and involves
* Preimplantation genetic diagnosis ( PGD ) involves the use of genetic screening mechanisms such as Fluorescent In Situ Hybridization ( FISH ) or Comparative Genomic Hybridization ( CGH ) to help identify genetically abnormal embryos and improve healthy outcomes.
Genomic and gene
* Genomic evolution, like horizontal gene transfer, genome fusions in endosymbioses, and adaptive changes in genome size.
Genomic duplication and triplication of the gene appear to be a rare cause of Parkinson's disease in other lineages, although more common than point mutations.
& Lupski, J. R. Genomic rearrangements and gene copy-number alterations as a cause of nervous system disorders.
Genomic and genetic
* Genomic Standards Consortium, an organization dedicated to standardizing genetic terminology
According to the Institute for Genomic Research ( TIGR ), the closest kin they could find in the database in 1996 were the Ngobe people of Panama, but the later research has shown her to share genetic patterns found in people from the Andes.
Genomic amplification occurs when a cell gains many copies ( often 20 or more ) of a small chromosomal region, usually containing one or more oncogenes and adjacent genetic material.
Genomic and sequence
The so-called shotgun sequencing technique ( which was used, for example, by The Institute for Genomic Research to sequence the first bacterial genome, Haemophilus influenzae ) does not produce entire chromosomes.
The short cDNA sequence fragments discovered by this method are called expressed sequence tags ( ESTs ), a name coined by Anthony Kerlavage at The Institute for Genomic Research.
Shortly afterward, in 1996, the first genome sequence for an archaeon, Methanococcus jannaschii, was completed, again by The Institute for Genomic Research.
* Genomic sequence
* Locus Reference Genomic, DNA sequence format
Genomic and .
The first genome annotation software system was designed in 1995 by Dr. Owen White, who was part of the team at The Institute for Genomic Research that sequenced and analyzed the first genome of a free-living organism to be decoded, the bacterium Haemophilus influenzae.
Genomic knowledge of the genes involved in diseases, disease pathways, and drug-response sites are expected to lead to the discovery of thousands more new targets.
The first bacterial genome to be sequenced was that of Haemophilus influenzae, completed by a team at The Institute for Genomic Research in 1995.
from the Laboratory of Genomic Diversity Study, part of the National Cancer Institute of the United States.
Genomic analysis of cultivated coconut ( Coco nucifera L .) has shed light on the movements of Austronesian peoples.
* MIT OpenCourseWare HST. 512 Genomic Medicine A free, self-study course in genomic medicine.
* Puente XS, Sanchez LM, Overall CM, Lopez-Otin C. Human and Mouse Proteases: a Comparative Genomic Approach.
* Puente XS, Lopez-Otin C. A Genomic Analysis of Rat Proteases and Protease Inhibitors.
Genetics company, Signature Genomic Laboratories and technology company, Itron are headquartered in the city.
Originally headquartered in Rockville, Maryland ( relocated to Alameda, California ), it was established in May 1998 by PE Corporation ( later renamed to Applera ), with Dr. J. Craig Venter from The Institute for Genomic Research ( TIGR ) as its first president.
Genomic DNA consists of two antiparallel and reverse complementary strands, each having 5 ' and 3 ' ends.
imprinting and is
Finally, Teg is awakened by Sheeana using imprinting techniques.
Appropriate expression of imprinted genes is important for normal development, with numerous genetic diseases associated with imprinting defects including Beckwith – Wiedemann syndrome, Silver – Russell syndrome, Angelman syndrome and Prader – Willi syndrome.
In insects, imprinting describes the silencing of the paternal genome in males, and thus is involved in sex determination.
This process of erasure and reprogramming is necessary such that the current imprinting status is relevant to the sex of the individual.
The control of expression of specific genes by genomic imprinting is unique to therian mammals ( placental mammals and marsupials ) and flowering plants.
A widely accepted hypothesis for the evolution of genomic imprinting is the " parental conflict hypothesis.
" Also known as the kinship theory of genomic imprinting, this hypothesis states that the inequality between parental genomes due to imprinting is a result of the differing interests of each parent in terms of the evolutionary fitness of their genes.
In support of this hypothesis, genomic imprinting has been found in all placental mammals, where post-fertilisation offspring resource consumption at the expense of the mother is high ; although it has also been found in oviparous birds where there is relatively little post-fertilisation resource transfer and therefore less parental conflict.
However, our understanding of the molecular mechanisms behind genomic imprinting show that it is the maternal genome that controls much of the imprinting of both its own and the paternally-derived genes in the zygote, making it difficult to explain why the maternal genes would willingly relinquish their dominance to that of the paternally-derived genes in light of the conflict hypothesis.
Others have approached their study of the origins of genomic imprinting from a different side, arguing that natural selection is operating on the role of epigenetic marks as machinery for homologous chromosome recognition during meiosis, rather than on their role in differential expression.
The removed egg hatches in an incubator and is raised with a condor handpuppet to prevent human imprinting, while the second egg is raised by its parents.
DNMT1 is essential for proper embryonic development, imprinting and X-inactivation.
These are normal genetic diseases caused by gene deletions or inactivation of the genes, but are unusually common because individuals are essentially hemizygous because of genomic imprinting, and therefore a single gene knock out is sufficient to cause the disease, where most cases would require both copies to be knocked out.
The best-known case of imprinting in human disorders is that of Angelman syndrome and Prader-Willi syndrome — both can be produced by the same genetic mutation, chromosome 15q partial deletion, and the particular syndrome that will develop depends on whether the mutation is inherited from the child's mother or from their father.
This is due to the presence of genomic imprinting in the region.
Beckwith-Wiedemann syndrome is also associated with genomic imprinting, often caused by abnormalities in maternal genomic imprinting of a region on chromosome 11.
0.189 seconds.