However, the problem still remained insurmountable, until in 1953 Max Perutz discovered that the phase problem in analysis of the diffraction patterns could be solved by multiple isomorphous replacement — comparison of patterns from several crystals ; one from the native protein, and others that had been soaked in solutions of heavy metals and had metal ions introduced in different well-defined positions.

( However, post-war publications by people concerned with the project ( e. g., Perutz and Goodeve ) all restore the proper ( one ' B ' and three ' K's ) spelling.

However, by comparing the TV snatches, two different radio station re-runs, and the censored Los Angeles Times version, I found that the radio stations had edited out questions ( ABC removed the one regarding Laos ) or even a paragraph out of the middle of the President's answer.

However few fossils have been found, of the Menyanthaceae-Asteraceae clade in the Oligocene, about 29 Mya.

However, another randomized controlled trial found primary closure led to 35 % failing to heal primarily and primary closure longer median number of days to closure ( 8. 9 versus 7. 8 ).

However, details of these beliefs can be found in almost everything he wrote, from his early Summa de bono to his last work, the Summa theologiae.

However, should he decide to testify, he is subject to cross-examination and could be found guilty of perjury.

" However some earlier high zinc, low iron brasses such as the 1530 Wightman brass memorial plaque from England may have been made by alloying copper with zinc and include traces of cadmium similar those found in some zinc ingots from China.

However, the 9 / 11 Commission found that although " former Sudanese officials claim that Sudan offered to expel Bin Laden to the United States ", " we have not found any reliable evidence to support the Sudanese claim.

However, Beethoven did not retain this version, and kept rewriting until he had found its final form, with the words < em lang =" de ">" O Freunde, nicht diese Töne "</ em > (" O friends, not these tones ").

However, the disease found in northern Europe ( including the UK ) in 2006 and 2007 has been caused by serotype 8.

However, certain Zarubintsy elements remained, found scattered throughout neighbouring areas of eastern Europe.

However, the strict acrostic style of four of the five poems is not found at all in the Book of Jeremiah itself and Jeremiah's name is not found anywhere in the book itself ( nor any other name, for that matter ), so authorship of Lamentations is disputed.

However, before reaching the transition temperature, the specific heat of the superconductor becomes even higher than that of the normal conductor ( measured immediately above the transition ) and the ratio of these two values is found to be universally given by 2. 5.

However, the 3DS and its predecessor the DSi lack the Game Boy Advance slot found on the DS and DS Lite, causing certain titles to lose functionality when played on the systems.

However, Kusche's research showed that the unclassified version of the Air Force investigation report stated that the debris field defining the second " crash site " was examined by a search and rescue ship, and found to be a mass of seaweed and driftwood tangled in an old buoy.

However, this statement for integers can be found already in the work of another French mathematician, Claude Gaspard Bachet de Méziriac ( 1581 – 1638 ).

However, no real evidence has been found for this.

However, the top of the system is sharply defined, being placed at an iridium-rich layer found worldwide that is believed to be associated with the Chicxulub impact crater in Yucatan and the Gulf of Mexico.

However he, and many refugees, also report that cannibalism was practiced non-ritually when there was no food to be found.

Most cycle deaths result from a collision with a car or heavy goods vehicle, both motorist and cyclist having been found responsible for collisions However, around a fifth of non-fatal injuries to cyclists do not involve any other person or vehicle.

However, one group of researchers have found that carob seeds in fact have typical variability compared to the seeds of other species.

However, contemporaneous representations of hybrid centaurs can be found in archaic Greek art.

However, since the contras failed to win widespread popular support or military victories within Nicaragua, since opinion polls indicated that a majority of the U. S. public was not supportive of the contras, since the Reagan administration lost much of its support regarding its contra policy within Congress after disclosure of CIA mining of Nicaraguan ports, and since a report of the Bureau of Intelligence and Research commissioned by the State Department found Reagan's allegations about Soviet influence in Nicaragua " exaggerated ", Congress cut off all funds for the contras in 1985 by the third Boland Amendment.

However, because of the Reid v. Covert decision, the U. S. adds a reservation to the text of every treaty that says, in effect, that the U. S. intends to abide by the treaty, but if the treaty is found to be in violation of the Constitution, then the U. S. legally can't abide by the treaty since the U. S. signature would be ultra vires.

However, the problem of consumer acceptability remains.

However, a major problem here is one of scale of processing ; ;

However needed this may be, the fundamental problem is not information but active commitment to the total mission of the church of Christ in the world.

However, the problem of infinite charge of the universe remains.

However, Hume admits that there is one objection to his account: the problem of " The Missing Shade of Blue ".

However, this left many universities with the problem of supporting IP on their many LocalTalk-equipped Macs.

However, false advertising and so-called " quack " advertisements became a problem, which ushered in the regulation of advertising content.

However, the problem is being addressed by community organizations and city government: Trees Atlanta, a non-profit organization founded in 1985, has planted and distributed over 75, 000 shade trees in the city, while Atlanta ’ s government has awarded $ 130, 000 in grants to neighborhood groups to plant trees.

" However, he also added, " Another movie ... the problem is it takes a year and half, two years, two and a half years — maybe — to do that right.

However, beyond this theoretical significance, efficient and scalable algorithms for SAT that were developed over the last decade have contributed to dramatic advances in our ability to automatically solve problem instances involving tens of thousands of variables and millions of constraints.

However, despite the success of Drude's free electron model, it had one notable problem, in that it was unable to correctly explain the electronic contribution to the specific heat of metals, as well as the temperature dependence of resistivity at low temperatures.

However, this problem has been alleviated somewhat by the development of the TransMilenio Bus Rapid System and the restriction of vehicles through a daily, rotating ban on private cars depending on plate numbers.

( However, the intersection of a context-free language and a regular language is context-free, so if were a regular language, this problem becomes decidable.

However, only a couple of months later a new problem arose: the company that commercially ran the circuit ( CENAV ), called in the receiver and went out of business, marking the end of " Circuit van Zandvoort ".

However, it remains difficult to find a solution to the coronal heating problem as these structures are being observed remotely, where many ambiguities are present ( i. e. radiation contributions along the LOS ).

However, Russell's theory analyses proper names into a logical structure which makes sense of this problem.

However, centuries of efforts failed to find a solution to this problem, until Pierre Wantzel published a proof in 1837 that such a construction was impossible.

However, combining the therapy with chemotheraputic treatments can help to solve this problem.

However, this is not a serious problem ; we have formulated a very simplistic hidden variable theory, and a more sophisticated theory might be able to patch it up.

However, if there is no " obvious " Euclidean function, then determining whether R is a PID is generally a much easier problem than determining whether it is a Euclidean domain.

However, the roots of the problem lay deeper in changing economic and social circumstances.

However, given the right problem, the use of an appropriate 4GL can be spectacularly successful as was seen with MARK-IV and MAPPER ( see History Section, Santa Fe real-time tracking of their freight cars – the productivity gains were estimated to be 8 times over COBOL ).

However, posted limits are in place on many dangerous or congested stretches as well as where traffic noise or pollution poses a problem.

However, complications can arise in the many-body problem.

However, push IMAP has not been generally accepted and current IETF work has addressed the problem in other ways ( see the Lemonade Profile for more information ).