However, the potential for clozapine to cause toxic side effects, including agranulocytosis, limits its usefulness.

However, technologists such as Bill Joy have warned of the potential power which genetic engineering might place in the hands of future bio-terrorists.

However, they are much less toxic than their predecessors, the barbiturates, and death rarely results when a benzodiazepine is the only drug taken ; however, when combined with other central nervous system depressants such as alcohol and opiates, the potential for toxicity and fatal overdose increases.

However, the Ionian Revolt had directly threatened the integrity of the Persian empire, and the states of mainland Greece remained a potential menace to its future stability.

However, Pedro de Valdivia, captain of the army, realizing the potential for expanding the Spanish empire southward, asked Pizarro's permission to invade and conquer the southern lands.

However, he allowed both Plectrude and the young Theudoald to live and treated them with kindness — unusual for those times, when mercy to a former gaoler, or a potential rival, was rare.

However, the rebellion of Tacfarinas had shown how exposed Africa Proconsularis was to its west and how the Mauretanian client kings were unable to provide protection to the province, and it is thus possible that Caligula's expansion was a prudent response to potential future threats.

However, Khrushchev and Malenkov were able to gather enough support for Beria's ouster, but only when a rumour of a potential coup led by Beria began to take hold within the party leadership.

However, a mulatto who escaped the destruction of Syn's previous ship stowed away in Clegg's ship and accused him before the crew ; Clegg quelled the potential mutiny by having the mulatto's tongue cut out, marooning him on a coral reef and violently killing Yellow Pete, the ship's Chinese cook, who represented the crew in their wish to rescue the mulatto.

However, these potential bite marks were first noticed in photographs years after the trials and were not inspected by a board-certified medical examiner until four years after the murders.

However, the reactions are reversible and the role of a particular electrode in a cell depends on the relative oxidation / reduction potential of both electrodes.

In order for this reaction to occur the power supply should provide at least a potential of 4 V. However, larger voltages must be used for this reaction to occur at a high rate.

However, it was to take another three years, and a change of coach, before the team's obvious potential was translated into tangible success.

However, this is a specific property of hydrogen and is no longer true for more complicated atoms which have a ( effective ) potential differing from the form 1 / r ( due to the presence of the inner electrons shielding the nucleus potential ).

However, some states are the subject of potential irredentism from their inception.

However, in order to not limit potential detainee's freedoms too much it is characterized by the time limit of near future.

However, more recently researchers have brought attention to potential underlying causes of OCBs, including social pressure, coercion, and other external forces.

However, according to Painter unlike the Testimonium this issue has not generated a great deal of controversy, although viewed as a potential reason for doubting authenticity.

However, other scientists have written that " the full potential PCR was not realized " until Mullis ' work in 1983, and that Mullis ' colleagues failed to see the potential of the technique when he presented it to them.

However, it soon became apparent that the Slipstream project had the potential to be much more than a peripheral.

However, there is also significant potential for extremes of hot and cold swings in temperature all year long.

However shielded twisted pair was used in IBM's Token Ring implementation, and in 1984 StarLAN showed the potential of simple unshielded twisted pair by using Cat3 — the same simple cable used for telephone systems.

However in 2010, only 330, 000 passengers of a potential 11 million Tube passengers claimed compensation for delays.

" However, as Stocking notes, Tylor mainly concerned himself with describing and mapping the distribution of particular elements of culture, rather than with the larger function, and he generally seemed to assume a Victorian idea of progress rather than the idea of non-directional, multilineal cultural development proposed by later anthropologists.

However, Rieux does not function as a first-person narrator.

However, in CL it is necessary to explicitly refer to the function namespace when passing a function as an argument — which is also a common occurrence, as in the example above.

However, alternative analysis suggests that the nominal particles do not function as clitics, but as phrasal affixes.

However, it is known that cortisone impairs memory function by reducing the blood flow in the right parahippocampal gyrus, left visual cortex, and the Cerebellum.

However, some resolvers function more simply by communicating only with a single name server.

However, if there is no " obvious " Euclidean function, then determining whether R is a PID is generally a much easier problem than determining whether it is a Euclidean domain.

However, it took a few more decades until the new regulation was universally accepted and the new court actually began to function ; only in 1512 would the Imperial Circles be finalised.

However, they did not make any conclusions regarding the specific function of DNA as hereditary material, and only said that it must have some undefined role.

However, the expression sin < sup >− 1 </ sup > x usually does not represent the multiplicative inverse to sin x, but the inverse of the sine function applied to x ( actually a partial inverse ; see below ).

However in Stirner's political thinking there can be found a surprising convergence with poststructuralist theory, particularly with regard to the function of power.

However, the latter chip was necessary in order to provide the FERR signal to the mainboard and appear to function as a normal floating point unit.

However, the reason for this correction to the partition function remained obscure until the discovery of quantum mechanics.

However, in the untyped lambda calculus, there's no way to prevent our function from being applied to truth values, or strings, for instance.

However, it can be made invariant by making the inertial mass of an object a function of velocity:

However, its function has evolved from and replaced the macro languages that were originally included in some of these applications.

However, on average and across the most commonly studied variables, acquiring firms ' financial performance does not positively change as a function of their acquisition activity.

However, like methadone, buprenorphine produces similar cognitive dehabilitation in multiple areas of mental function in both memory and timed choice task tests, which may persist after cessation of substitution treatment.

However, none of this research and criticism was originally known to most of the English-language commentators, by function of the dates when they were writing and, to some extent, of the language in which it was written.

However, in the context of topology, sequences do not fully encode all information about a function between topological spaces.

However, in this circuit V < sub >−</ sub > is a function of V < sub > out </ sub > because of the negative feedback through the R < sub > 1 </ sub > R < sub > 2 </ sub > network.

However, the physiological function of the prion protein remains a controversial matter.

However, the function of the prime minister has evolved with increasing power.

However licensing was gradually liberalised after the 1960s, until contested licensing applications became very rare, and the remaining administrative function was transferred to Local Authorities in 2005.