However, others argue that the effects of the high concentrations of macromolecules in cells extend throughout the cytosol and that water in cells behaves very differently from the water in dilute solutions.

However, this value is only approximate, as reaction quotient is defined in terms of ion activities which can be approximated with the concentrations as calculated here.

However, carbon dioxide has an advantage in this respect as it kills organisms through hypercarbia and depending on concentration hypoxia and, requiring concentrations of above 35 %, or so.

However, HDL carries many lipid and protein species, several of which have very low concentrations but are biologically very active.

However, in addition to lysosomotropism, high tissue concentrations and long elimination half-life is explained also by lipophilicity and absorption of drugs to fatty tissue structures.

However, when these commercial varieties turn green, even they can approach concentrations of solanine of 1000 mg / kg ( 1000 ppmw ).

However, it is possible to measure the concentration of hydrogen ions directly, if the electrode is calibrated in terms of hydrogen ion concentrations.

However, mutant p53 proteins often do not induce MDM2, and are thus able to accumulate at very high concentrations.

However, local eruptions of volcanoes or other events that give off large amounts of carbon dioxide can reduce local concentrations of carbon-14 and give inaccurate dates.

However, baking and brewing yeasts typically belong to different strains, cultivated to favour different characteristics: baking yeast strains are more aggressive, to carbonate dough in the shortest amount of time possible ; brewing yeast strains act slower, but tend to produce fewer off-flavours and tolerate higher alcohol concentrations ( with some strains, up to 22 %).

However, the ozone hole is most usually measured not in terms of ozone concentrations at these levels ( which are typically of a few parts per million ) but by reduction in the total column ozone, above a point on the Earth's surface, which is normally expressed in Dobson units, abbreviated as " DU ".

However, use of activities is very inconvenient, so the equilibrium constant is usually divided by the quotient of activity coefficients, to become a quotient of concentrations.

However, in the case of the proton, the evidence suggested three distinct concentrations of charge ( quarks ) and not one.

However, DSO ores can contain significantly higher concentrations of penalty elements, typically being higher in phosphorus, water content ( especially pisolite sedimentary accumulations ) and aluminum ( clays within pisolites ).

However, a study, published in the Journal of the American Water Resources Association ( April 2008 ) completed by researchers at Northeastern University found high concentrations of E. coli bacteria in the Charles River after a long period of no rain.

However, his report contains the assumption that lower concentrations are required for delousing than to kill humans and other warm blooded creatures ; in fact, with their simpler structures and slower metabolisms, insects are more resistant to such gross metabolic poisons than mammals.

However, there is not always a precise distinction between them and bactericidal antibiotics ; high concentrations of some bacteriostatic agents are also bactericidal, whereas low concentrations of some bacteriocidal agents are bacteriostatic.

However, there are circumstances where the activity and the concentration are significantly different and, as such, it is not valid to approximate with concentrations where activities are required.

However it was argued that the concentrations of the alternative energy substrates used in these experiments were non-physiological and the GABA-shift was instead caused by changes in pH resulting from the substrates acting as " weak acids ".

However, Kesselring divined the Allies ' intentions ; on 18 November, Lemelsen had signaled Kesselring to the effect that the Allied concentrations on the coast led him to expect the main attack on his left wing.

However, due to poor biodegradability, these chelating agents are found in alarmingly high concentrations in some water sources from which municipal tap water is taken.

However, subsequent German attacks closed in so tightly that further artillery concentrations could not be called in without hitting British positions.

However, the Lamm equation is most ideal for modeling concentrations of ideal, non-interacting solutes.

However, air observers have been use since the beginning of indirect fire and were quickly joined by air photography.

However, air show accidents are rare and where there is proper supervision air shows have impressive safety records.

However, they are now increasingly of low-floor design and optionally also ' kneel ' air suspension and have electrically or hydraulically extended under-floor ramps to provide level access for wheelchair users and people with baby carriages.

However since the Second World War land or sea battles have come to rely on air support.

However, unless the airflow is adjusted as well, the flame temperature will decrease because an increased amount of gas is now mixed with the same amount of air, starving the flame of oxygen.

However, its use in terrestrial applications is usually limited by its high reactivity with air.

However, it does suffer from nitrogen embrittlement, reacting with nitrogen from air and forming brittle nitrides at the high temperatures necessary to work the metal parts.

However, Empedocles of Acragas ( c. 495-c. 435 BC ) selected four archai for his four roots: air, fire, water and earth.

However, water conducts sound better than air, so the external ear is unneeded: it is a tiny hole in the skin, just behind the eye.

However when combined with land mines, snipers, barbed wire, and air cover, crossfire became a difficult tactic to counter in the early 20th century.

However, in scuba diving, nitrox is normally differentiated and handled differently from air.

However, some flutes, such as the whistle, gemshorn, flageolet, recorder, tin whistle, tonette, fujara, and ocarina have a duct that directs the air onto the edge ( an arrangement that is termed a " fipple ").

However in 1946, when Sir Miles Clifford arrived as governor, there were no air services, no roads outside Stanley and an indifferent sea service.

However, external services continued to be supplied almost exclusively by foreign airlines until Guyana Airways Corporation commenced regional air services in 1979.

However, it tarnishes quickly in moist air, forming a loosely adhering gadolinium ( III ) oxide ( Gd < sub > 2 </ sub > O < sub > 3 </ sub >), which spalls off, exposing more surface to oxidation.

However, it reacts with water and rusts readily, and will also burn in air when heated.

However, the court players may catch and touch the ball in the air within it as long as the player starts their jump outside the zone and releases the ball before they land ( landing inside the perimeter is allowed in this case as long as the ball has been released ).

However if the region of air breakdown extends to another conductor at a different voltage it will create a conductive path between them, and a large current will flow through the air, creating an " electric arc ".

However, when exposed to moist air at room temperature, lanthanum oxide forms a hydrated oxide with a large volume increase.

However, Luftstreitkräfte, or " air armed force ", is also sometimes used as a translation of " air force ".

However, this does not take into the account that Germany's economic situation suffered from limited resources – mainly raw materials like oil and aluminium – which did not provide for much beyond a tactical air force.