However, recent publications indicate that different alkaloids may be at work to achieve mild stimulation versus sedation: whereas higher concentrations of mitragynine are attributed to act as a sedative, 7-hydroxymitragynine appears to be a significant alkaloid for reducing stress associated with opioid craving.

However, early efforts to isolate an active alkaloid were unsuccessful.

However, Dr. Mendel Friedman of the federal Department of Agriculture contradicts this claim stating that tomatine, a relatively benign alkaloid, is the tomato alkaloid while solanine is found in potatoes.

However, on February 6, 2004 the Food and Drug Administration ( FDA ) banned the sale of ephedra and its alkaloid, ephedrine, for use in weight loss formulas.

However, applets have very little control over web page content outside the applet dedicated area, so they are less useful for improving the site appearance in general ( while applets like news tickers or WYSIWYG editors are also known ).

However, false advertising and so-called " quack " advertisements became a problem, which ushered in the regulation of advertising content.

However with decreased fat content there is decreased marbling of meat, which means the meat tenderness is reduced.

However the carcass value of double-muscled animals may be enhanced due to increased dressing yield, lean carcass content, and upgrading of some cuts leading to a higher proportion of higher valued cuts.

However, a large body of work uses the term chromosome regardless of chromatin content.

However, works such as the Great Soviet Encyclopedia, which were created in the public domain, exist as free content encyclopedias in other languages.

However, the local complaints had no effect on the content or release of the film.

However, in the last couple of years the British graffiti scene has been struck by self-titled ' art terrorist ' Banksy, who has revolutionized the style of UK graffiti ( bringing to the forefront stencils to aid the speed of painting ) as well as the content ; making his work largely satirical of the sociological state of cities, or the political climate of war, often using monkeys and rats as motifs.

However, the sulfur content of traditional gunpowders caused corrosion problems with Cordite Mk I and this led to the introduction of a range of sulfur-free gunpowders, of varying grain sizes.

However, applets have very little control over web page content outside the applet dedicated area, so they are less useful for improving the site appearance in general ( while applets like news tickers or WYSIWYG editors are also known ).

However, the nectar is still high in both water content and natural yeasts, which, unchecked, would cause the sugars in the nectar to ferment.

However, amino acid content is almost negligible in honey, accounting for only 0. 05 – 0. 1 % of the composition.

However, 1-inch-thick green Red Oak requires about 28 days to dry down to a moisture content of 8 %.

However, the conclusion was ambiguous as the overall content was above that expected of a male, and variations across the body may have been due to environmental factors.

However, in 2010 the Tokyo Metropolitan Government passed a bill to restrict harmful content.

However, Salon's David Futrelle opined that such content was very much a part of Mads past:

However, there is an enormous amount of non-annotated data available ( including, among other things, the entire content of the World Wide Web ), which can often make up for the inferior results.

However, free content has preserved the requirement ( present in both open source and free software ) that licenses allow commercial use and adaptation.

However, the narrower definition used in the Open Definition effectively limits open content to libre content ; any free content license would qualify as an open content license.

However, not only because of the message conveyed, but also Bearden ’ s vernacular realism represented in the work makes The Visitation noteworthy ; Bearden describes two figures in The Visitation somewhat realistically but does not fully follow the pure realism by distorting and exaggerating some parts of their body, to “ convey an experiential feeling or subjective disposition .” Bearden ’ s quotation also demonstrates his supportive view to vernacular realism: “ the Negro artists must not be content with merely recording a scene as a machine.

However, formal reasoners are content to contemplate axiomatically independent and sometimes mutually contradictory systems side by side, for example, the various alternative geometries.

However, while the critique from the right emphasized moral degeneracy ascribed to sexual and racial influences within popular culture, Adorno located the problem not with the content, but with the objective realities of the production of mass culture and its effects, e. g. as a form of reverse psychology.

However, the narcotic properties of coca were known only locally until 1786, when Lamarck listed the leaf in his botanical encyclopedia.

However the reduction in cultivation may not have actual effects on cocaine production, as recent advances in coca growing and more efficient processing methods allow for greater cocaine yield.

However, the reader is made aware of the truly addictive effects of the drug when rats, who have found the coca ( Erythroxylum coca ), become seriously addicted and scour the ship looking for it.

However, eradication efforts have been hampered by the lack of a suitable replacement crop for rural communities that have cultivated coca for generations.

However, the new legislation did not affect the coca ingredient ( cocaine ), which remained in the formula until the end of the 19th century.

However, a March 2005 report by the ONDCP indicated that despite record aerial spraying of over 1, 300 km² of coca in Colombia in 2004, the total area under coca cultivation remained " statistically unchanged " at 1, 140 km².

However, the increasing U. S. involvement in El Chapare with the tacit support of the Bolivian government angered Evo, who returned to campaigning on behalf of the coca growers.

However this leaves no prize for herself.

However, the argument concludes that the conceptual challenge of bare particulars leaves a bundle of properties and nothing more as the only possible conception of an object, thus justifying bundle theory.

However, according to the architectural historian Vitruvius, the column was created by the sculptor Callimachus, probably an Athenian, who drew acanthus leaves growing around a votive basket.

However in the DVD, the Davros Connections, director Gary Russell points out that the explosion of Davros ' life-support chair leaves the listener to believe there is little of Davros left.

However, it is argued that this approach fails to properly define euthanasia, as it leaves open a number of possible actions which would meet the requirements of the definition, but would not be seen as euthanasia.

However, subsequent bombardment from American naval vessels leaves it gravely wounded.

However, the composition and origin of the magma which differentiates into granite, leaves certain geochemical and mineral evidence as to what the granite's parental rock was.

However, while this may suggest that perceived OBEs are a type of lucid dream which takes place in a dream environment that mimics the actual environment of the dreamer, this falls short of supporting the idea that some conscious form of the dreamer actually leaves the body and perceives their external environment while still in a sleeping state.

However, neither the leaves nor paper were as durable as the metal document in the hot, humid climate.

However, the statute of limitation is suspended during his term, and enquiries and prosecutions can be restarted, at the latest one month after he leaves office.

However, Nero leaves the battle to continue his assault on the planet Vulcan.

However, Singapore soon leaves this new country,

However, when the bowl becomes full, she leaves to pour out the venom.

However, he knows that he has been seen and so leaves, on pretense of finishing a task, and gives the key to his room to the abbot, who then goes to see the girl for himself.

However, were the diacritics to be kept, the system reveals a symmetry that leaves no overlap:

However, his relationship with Buffy gradually disintegrates, and in Season Five he leaves to join another army unit.

However, he returns several times after Drusilla leaves him.

However, defining physical objects in terms of fundamental particles ( e. g. quarks ) leaves open the question of what is the nature of a fundamental particle and thus asks what categories of being can be used to explain physical objects.

However, true leaves and cotyledons are developmentally distinct.

However, the leaves are believed to contain also an additional, unidentified toxin, which might be an anthraquinone glycoside ( also known as senna glycosides ).

However, the attribution was disputed by reports showing the plant extracts from fresh leaves contained another substance more behaviorally active than cathine.

However, at his death, Baldwin leaves Friday a subsidy to finance her emigration to any planet of her choice, except Olympia, where the " supermen " went at some indeterminate point in the past.

However, she refuses to apologize for her past, and Holden leaves feeling angry and confused.

However, the Toxicodendron radicans ( Poison Ivy ) generally has trifoliolate leaves.