However, treatment resistance is widely defined as lack of therapeutic response to two antidepressants at adequate doses for an adequate duration and with good compliance.

However, the science of Ayurveda looks upon aconite as a therapeutic entity.

However, many practitioners continue to rely on projective testing, and some testing experts ( e. g., Cohen, Anastasi ) suggest that these measures can be useful in developing therapeutic rapport.

However, some exemptions are made for athletes who take banned substances for therapeutic use, and athletes are not sanctioned for usage in these cases, such as Kim Collins ' failed drug test due to asthma medication.

However, extensive clinical trials using recombinant human leptin as a therapeutic agent for treating obesity in humans have been inconclusive because only the most obese subjects who were given the highest doses of exogenous leptin produced statistically significant weight loss.

However, environmental factors and therapeutic interferences may cause some discrepancies between tumor burden and bioluminescence intensity in relation to changes in proliferative activity.

However, the Trudeau bill made an exception for abortions performed in a hospital with the approval of that hospital ’ s three-doctor therapeutic abortion committee.

However, it is well documented that very little therapeutic activity occurred in the new asylum system, that medics were little more than administrators who seldom attended to patients, and then mainly for other physical problems.

However, Fluosol-DA remains the only oxygen therapeutic ever fully approved by the FDA.

However the therapeutic use of blood comes with its significant risks which are enormous.

However, due to her belief that Trauma could and should use his powers in a therapeutic nature, Henry Peter Gyrich, who intends to use Trauma as a weapon for the Initiative, is quick to dismiss her from Camp Hammond once she provides Trauma with enough training in his powers.

However, azapirones are considered less effective in controlling symptoms in comparison and also require several weeks for their therapeutic benefits to come to prominence.

However, it is poorly absorbed when used topically, and usually requires oral dosing to reach the infection with therapeutic levels inside of a stye.

However, these problems associated with histocompatibility may be solved using autologous donor adult stem cells, therapeutic cloning, stem cell banks or more recently by reprogramming of somatic cells with defined factors ( e. g. induced pluripotent stem cells ).

However, expressive arts therapy is its own therapeutic discipline, an inter-modal discipline where the therapist and client move freely between drawing, dancing, music, drama, poetry, etc.

However, there is little evidence that a low-salicylate diet is beneficial for patients with AERD, and current clinical trials are underway to determine whether or not the difficult dietary changes truly provide worthwhile therapeutic improvement for these patients.

However, virtual colonoscopy is considered the gold standard by some professionals because it permits complete visualization of the entire colon, hence providing the opportunity to identify precancerous polyps and cancer, and then to do diagnostic biopsies or therapeutic removal of these lesions, as soon as possible.

However, in studies carried out after the clinical efficacy of cyclophosphamide was demonstrated, phosphoramide mustard proved to be cytotoxic in vitro ( footnote omitted ), but to have a low therapeutic index in vivo.

However, therapeutic cloning may be thought of as ethical, as it does not result in another human being.

However, most levodopa is decarboxylated to dopamine before it reaches the brain, and since dopamine is unable to cross the blood – brain barrier, this translates to little therapeutic gain with strong peripheral side effects.

However, the therapeutic use of water precedes this popular revival.

However, because of the small difference between therapeutic and toxic dose, epibatidine has never been used in humans.

" However, their operation is not primarily pharmaceutical, as they are not applied to or ingested by those who are sick, and perhaps bilongo is more accurately translated as " therapeutic substances .".

However, unlike anxiolytic compounds ( eg, benzodiazepines ) which exert their therapeutic effects through binding to GABA < sub > A </ sub >, GABA < sub > B </ sub >, and benzodiazepine receptors, pregabalin neither binds directly to these receptors nor augments GABA < small >< sub > A </ sub ></ small > currents or affects GABA metabolism ( Pfizer Inc. 2006 ).

However, because this vulnerability is mutual, it is to the advantage of neither side to destroy the opponent's cities, at least so long as the opponent has nuclear weapons with which to effect reprisal.

However, if the excited atom has been previously ionized, in particular if one of its inner shell electrons has been removed, a phenomenon known as the Auger effect may take place where the quantity of energy is transferred to one of the bound electrons causing it to go into the continuum.

However, the particulates responsible for acid rain ( sulfur dioxide and nitrogen oxides ) do have an adverse effect.

However other reports indicate that piracy does not have an adverse effect on the entertainment industry.

However, there still were several unsolved problems, most notably the description of superconductivity and the Kondo effect.

However, Pol Pot biographer David Chandler argues that the bombing " had the effect the Americans wanted – it broke the Communist encirclement of Phnom Penh ".

However, one might fix on non-psychological goods as the relevant effect.

However, while Muhammad Ali initiated the construction of public buildings in the city, those reforms had minimal effect on Cairo's landscape.

However, during 2006-8, several reviews of case reports and pilot studies have failed to confirm this effect, collectively indicating no statistically significant interaction between daily consumption of 250 mL cranberry juice and warfarin in the general population.

However, some drugs have a better side effect profile than others, enabling doctors to adjust treatment regimens to the advantage of patients in certain situations.

However, because of the Reid v. Covert decision, the U. S. adds a reservation to the text of every treaty that says, in effect, that the U. S. intends to abide by the treaty, but if the treaty is found to be in violation of the Constitution, then the U. S. legally can't abide by the treaty since the U. S. signature would be ultra vires.

However, the cost of calculators fell as components and their production techniques improved, and the effect of economies of scale were felt.

However, barbarian raids during the reign of Marcus Aurelius and removal of statues and other riches ( in effect looting ) by Constantine I caused it to decay.

However, when the slew rate of the current is not so severe ( e. g. Line frequency ) the effect can be safely ignored.

However, this argument has been described as an example of the fallacy of a statistical confounding effect ; it is now known that a herpesvirus, potentiated by HIV, is responsible for AIDS-associated KS.

However, the effect of chewing on the intake of macronutrients, such as sugars, fats, and proteins has not been observed.

However, not only did he reject the title of Dominus during his reign, but since he issued no official documentation or coinage to this effect, historians such as Brian Jones contend that such phrases were addressed to Domitian by flatterers who wished to earn favors from the emperor.

However, the later discovery of the photoelectric effect demonstrated that under different circumstances, light can behave as if it is composed of discrete particles.

" However, it also potentially has the effect of prohibiting tourist photographs of the tower at night from being published, as well as hindering non-profit and semi-commercial publication of images of the tower.

However, one might fix on non-psychological goods as the relevant effect.

However, after the new Constitution took effect, the Congress passed a code of ethics which imposes penalties on members who defy their party leadership on key votes.

However in nonlinear media, such as some crystals, interactions can occur between light and static electric and magnetic fields — these interactions include the Faraday effect and the Kerr effect.

However, the effect did not become widely known until 1820, when Ørsted performed a similar experiment.

However, the view that there is no causal instantaneous effect has also been proposed within the Copenhagen interpretation: in this alternate view, measurement affects our ability to define ( and measure ) quantities in the physical system, not the system itself.