If it were simple to ascertain the properties required to develop a lead discovered in vitro to one that is active in vivo, drug discovery would be as reliable as drug manufacturing.

If a drug is cleared too quickly from the body, this could force a patient to use high doses, but with drug delivery systems clearance can be reduced by altering the pharmacokinetics of the drug.

He said, " If every parent uses this chip wisely, it can become a powerful voice against teen violence, teen pregnancy, teen drug use, and for both learning and entertainment ," as he signed the law on February 8, 1996.

If a brain-dead individual is not an organ donor, ventilator and drug support is discontinued and cardiac death is allowed to occur.

If these drugs were legal and sold in a fair, competitive market, it would drive the price of these drugs down, which would result in fewer secondary crimes from drug addicts.

If the drug pilocarpine is administered, the pupils will constrict and accommodation is increased due to the parasympathetic action on the circular muscle fibers, conversely, atropine will cause paralysis of accommodation ( cycloplegia ) and dilation of the pupil.

If the granulate has a low drug content, the active substance may be premixed with one of the ingredients prior to being added to the granulation vessel to ensure good content uniformity.

If the highest percentage of absorption of a drug takes place in the stomach, a coating that dissolves quickly and easily in acid will be selected.

If an ELISA test is used for drug screening at workplace, a cut-off concentration, 50 ng / ml, for example, is established, and a sample containing the standard concentration of analyte will be prepared.

If a dietary supplement claims to cure, mitigate, or treat a disease, it would be considered an unauthorized new drug and in violation of the applicable regulations and statutes.

If a drug that inactivates the amygdalae is injected, the animals had impaired memory for the task.

If any of these native internalization sequences are present in a therapeutic, then the drug will be internalized by, and kill, untargeted epithelial cells as well as targeted cancer cells.

If there are enough drugs for sale or supply then Gardaí can arrest but the drug will be seized and the name and address of the individual will be taken.

If police suspect someone has consumed cannabis they could be ordered to take a drug test, which is seen as a way to prove consumption.

If a brain-dead individual is not an organ donor, ventilator and drug support is discontinued and cardiac death is allowed to occur.

If so, a drug user may increase the amount of drug consumed in order to feel its effects, and end up taking very large amounts of the drug.

If this biological product can be formed properly, it could be used to deliver a drug to a specific tissue in the body, such as a tumor.

Simultaneous treatment of multiple disorders requires strict consideration of compatibility of drugs and detailed adherence of rules of rational drug therapy, based on E. M. Tareev ’ s principles, which state: “ Each non-indicated drug is contraindicated ” and B. E. Votchal said: “ If the drug does not have any side-effects, one must think if there is any effect at all ”.

If the voltage changes by a large enough amount, an all-or-none electrochemical pulse called an action potential is generated, which travels rapidly along the cell's axon, and activates synaptic connections with other cells when it arrives.

If the erroneous command persists for more than a predetermined time, differential pressure sensing activates a selector valve to isolate and remove the defective servovalve hydraulic pressure, permitting the remaining channels and servovalves to control the actuator ram spool.

If the player successfully activates enough notes in sequence, the track is " captured " and the section will play automatically for a number of bars, freeing the player to capture another section.

If used with a 3-button gamepad, button C cycles through the items, and button A activates the item.

If the yaw sensor detects more / less yaw than the steering wheel angle should create, the car is understeering or oversteering and ESC activates one of the front or rear brakes to rotate the car back onto its intended course.

If it is, then the control unit activates a solenoid valve that directs boost pressure to the turbocharger's pneumatically controlled wastegate actuator, which opens the wastegate to bypass exhaust gases from the turbocharger directly to the exhaust pipe, lowering turbo boost pressure until the knock subsides.

If a stimulus is perceived as a threat, a more intense and prolonged discharge of the locus ceruleus activates the sympathetic division of the autonomic nervous system ( Thase & Howland, 1995 ).

If a thirty-second countdown passes and no-one activates the switch, the doomsday weapon will fire and leave the surface of the Earth uninhabitable within one week.

If the circumstances are faced frankly it is not reasonable to expect this to be true.

If his dancers are sometimes made to look as if they might be creatures from Mars, this is consistent with his intention of placing them in the orbit of another world, a world in which they are freed of their pedestrian identities.

If a work is divided into several large segments, a last-minute drawing of random numbers may determine the order of the segments for any particular performance.

If they avoid the use of the pungent, outlawed four-letter word it is because it is taboo ; ;

If Wilhelm Reich is the Moses who has led them out of the Egypt of sexual slavery, Dylan Thomas is the poet who offers them the Dionysian dialectic of justification for their indulgence in liquor, marijuana, sex, and jazz.

If he is the child of nothingness, if he is the predestined victim of an age of atomic wars, then he will consult only his own organic needs and go beyond good and evil.

If it is an honest feeling, then why should she not yield to it??

If he thus achieves a lyrical, dreamlike, drugged intensity, he pays the price for his indulgence by producing work -- Allen Ginsberg's `` Howl '' is a striking example of this tendency -- that is disoriented, Dionysian but without depth and without Apollonian control.

If love reflects the nature of man, as Ortega Y Gasset believes, if the person in love betrays decisively what he is by his behavior in love, then the writers of the beat generation are creating a new literary genre.

If he is good, he may not be legal ; ;

If the man on the sidewalk is surprised at this question, it has served as an exclamation.

If the existent form is to be retained new factors that reinforce it must be introduced into the situation.

If we remove ourselves for a moment from our time and our infatuation with mental disease, isn't there something absurd about a hero in a novel who is defeated by his infantile neurosis??

If many of the characters in contemporary novels appear to be the bloodless relations of characters in a case history it is because the novelist is often forgetful today that those things that we call character manifest themselves in surface behavior, that the ego is still the executive agency of personality, and that all we know of personality must be discerned through the ego.

If he is a traditionalist, he is an eclectic traditionalist.

If our sincerity is granted, and it is granted, the discrepancy can only be explained by the fact that we have come to believe hearsay and legend about ourselves in preference to an understanding gained by earnest self-examination.

If to be innocent is to be helpless, then I had been -- as are we all -- helpless at the start.