The Medici family effectively ruled Florence on a hereditary basis, from 1434 – 1494, 1512 – 1527, 1531, until 1533, when Alessandro de Medici was created Duke of Florence, thereby turning Florence into a hereditary monarchy.

He was created a marshal of France, and in 1527 he again received the command of the army of Italy.

Born at Bar-le-Duc ( Lorraine ), Guise was the son of Claude, Duke of Guise ( created Duke of Guise in 1527 ), and his wife Antoinette de Bourbon.

In 1527, he created a map depicting Verrazzano's travels.

The demographic crises created by the plague forced the Duke of Bragança, in 1527 to carry out small land reforms in order to promote the settlement Monsaraz.

King Louis II died at Mohács, and in 1527, and the Hungarian parliament elected János Szapolyai as the new king of Hungary.

They were supported by different factions of the nobility in the Hungarian kingdom ; Ferdinand also had the support of his brother the Emperor Charles V. After defeat by Ferdinand at the Battle of Tarcal in September 1527 and again in the Battle of Szina in March 1528, Zápolya gained the support of Suleiman the Magnificent, the Ottoman Sultan.

In 1527 the Habsburgs inherited those titles, together with the Hungarian crown.

1450 died aft. 1527 ) paternal grandmother Dorottya de Garay, was from a prominent Hungarian noble family.

* Christoph Frankopan ( Hungarian: Kristóf ) ( died 1527 ).

Jovan Nenad ( also Jovan the Black or Tsar Jovan Nenad ; ; c. 1492 – 26 July 1527 ) was a 16th-century military commander of Serb mercenaries in the Kingdom of Hungary who took advantage of a Hungarian military defeat in the Battle of Mohács and subsequent struggle over the Hungarian throne to carve out his own state and styled himself emperor ( tsar ), ruling over a short-lived area.

At first, Jovan Nenad supported Zápolya, but Hungarian nobles, whose lands in Bačka he had taken, estranged Zápolya from him, so in the beginning of 1527, he switched to Ferdinand.

After his earlier work in c. 1527 he edited a map of Hungary, today known as Tabula Hungariae, from the manuscript of Lazarus Secretarius, a Hungarian clerk.

** Hungarian campaign of 1527 – 1528

On January 6, 1527, the Slavonian nobility distanced themselves from this election and nominated John Zápolya the rival claimant to the Hungarian throne instead.

The Last Judgment was painted by Michelangelo between 1535 – 1541, after the Sack of Rome of 1527 by mercenary forces from the Holy Roman Empire, which effectively ended the Roman Renaissance, just before the Council of Trent.

It was on March 12, 1527 that Babur drew forward his guns and a kind of defensive cover that moved on wheels and which served as a breastwork supporting them by his matchlock men and all his army.

Florence remained a republic until 1537, traditionally marking the end of the High Renaissance in Florence, but the instruments of republican government were firmly under the control of the Medici and their allies, save during the intervals after 1494 and 1527.

By 1527 the Spanish had formed a government and established Catholicism on the islands.

* John Hooker ( English constitutionalist ) ( c. 1527 – 1601 ) English writer, solicitor, antiquary, civic administrator and advocate of republican government

In 1527 he passed preliminary exams to become a government official, but re-entered Sungkyunkwan at the age of 33 and socialized with the scholar Kim In-hu.

On 5 July 1527 as Div Sultan arrived for a meeting of the government, Tahmasp shot an arrow at him.

John Hooker, John Hoker or John Vowell ( c. 1527 – 1601 ) was an English writer, solicitor, antiquary, civic administrator and advocate of republican government.

* John Hooker ( English constitutionalist ) ( c. 1527 – 1601 ) English writer, solicitor, antiquary, civic administrator and advocate of republican government

Hoping to establish a more orderly government, to reduce the authority of Cortés, and secure the authority of the Spanish crown in the New World, on December 13, 1527 the metropolitan government of Charles V in Burgos named a Real Audiencia to take over the government of the colony.

The first bishop was Julian Garces and the seat was established in 1527.

* Between 1527 and 1689, Speyer is the seat of the Imperial Chamber Court.

The election of his old Medici patron as Pope Clement VII sent him briefly back to Rome, but death threats and an attempted assassination from one of the victims of his pen, Bishop Giovanni Giberti, in July 1525, set him wandering through northern Italy in the service of various noblemen, distinguished by his wit, audacity and brilliant and facile talents, until he settled permanently in 1527, in Venice, the anti-Papal city of Italy, " seat of all vices " Aretino noted with gusto.

In his youth Ngawang Namgyal was enthroned as the Eighteenth Drukpa or throne-holder and " hereditary prince " of the traditional Drukpa seat and estate of Ralung () and recognized there as the immediate reincarnation of the Fourth Gyalwang Drukchen (), the " Omniscient " Pema Karpo () ( 1527 – 1592 ).

The oldest known document using the German word Alphorn is a page from a 1527 account book from the former Cistercian abbey St. Urban near Pfaffnau mentioning the payment of two Batzen for an itinerant alphorn player from the Valais.

* 1527 – Spanish and German troops sack Rome ; some consider this the end of the Renaissance.

* 1527 – Hermann Finck, German composer ( d. 1558 )

* 1527 – Jerome Emser, German theologian ( b. 1477 )

* March 20 – Jerome Emser, German theologian ( d. 1527 )

* December 28 – Hermann Finck, German composer ( b. 1527 )

Maximilian II ( 31 July 1527 – 12 October 1576 ) was king of Bohemia and king of the Romans ( king of Germany ) from 1562, king of Hungary and Croatia from 1563, emperor of the Holy Roman Empire of the German Nation from 1564 until his death.

Most damaging was the May 6, 1527, Spanish and German troops ' sacking Rome that for two decades all but ended the role of the Papacy as the largest patron of Renaissance art and architecture.

The High Renaissance period is traditionally taken to begin in the 1490s, with Leonardo's fresco of the Last Supper in Milan and the death of Lorenzo de ' Medici in Florence, and to have ended in 1527 with the sacking of Rome by the troops of Charles V. This term was first used in German ( Hochrenaissance ) in the early nineteenth century, and has its origins in the " High Style " of painting and sculpture described by Johann Joachim Winckelmann.

In 1527 with the Reformation High German language came in use and with it the first usage of the version of the town's name (" Ohlau ") is reported.

In July 1527, an army of German mercenaries invaded Hungary.

* Heinrich Finck ( 1444 or 1445 – 1527 ), German composer of the Renaissance

* Hermann Finck ( 1527 – 1558 ), German composer, music theorist and organist of the Renaissance, great-nephew of Heinrich Finck

Heinrich Finck ( 1444 or 1445 – 9 June 1527 ) was a German composer.

Hermann Finck ( 21 March 1527 – 28 December 1558 ) was a German composer.

Kettler was of an old Westphalian noble family and the ninth child of the German knight Gotthard Kettler zu Melrich ( mentioned 1527 – 1556 ) and his wife Sophie of Nesselrode.

Paul Hainzel ( 1527 – 1581 ) was a German astronomer and the mayor of Augsburg, Germany.

Jerome ( or Hieronymus ) Emser ( March 20, 1477 – November 8, 1527 ), German theologian and antagonist of Luther, was born of a good family at Ulm.

active part in organizing a reformed Roman Catholic Church in Germany, and in 1527 published a German version of the New Testament as a counterblast to Luther's.