In 1727, John Digges, an Irish nobleman of Prince George's County, Maryland, obtained a grant of of land where Hanover is now located from Charles Calvert, the fourth Lord Baltimore.

The earliest known garden buildings at Cliveden were both designed by Giacomo Leoni for Lord Orkney ; the Blenheim Pavilion ( c. 1727 ) was built to commemorate Orkney's victory as a general at the Battle of Blenheim.

** Edward Russell, 1st Earl of Orford ( 1653 – 1727 ), English naval officer and First Lord of the Admiralty

He held a variety of government and court positions including Lord Lieutenant of Leicestershire 1721 – 1779, Chancellor of the Duchy of Lancaster 1727 – 1736, Lord Steward of the Household 1755 – 1761, and Master of the Horse 1761 – 1766.

Simon Harcourt, 1st Viscount Harcourt, of Stanton Harcourt, Oxfordshire, PC ( December 1661 – 23 July or 28 December 1727 ) was Queen Anne's Lord Chancellor of Great Britain.

* John Sempill, 11th Lord Sempill ( d. 1727 )

* George Forrester, 5th Lord Forrester ( 1688 – 1727 )

Lord Ilay was one of the founders of the Royal Bank of Scotland in 1727, and acted as the bank's first governor.

Charles Jenkinson, 1st Earl of Liverpool PC ( 26 April 1727 – 17 December 1808 ), known as the Lord Hawkesbury between 1786 and 1796, was a British statesman.

Lord Breadalbane and Holland's elder son Duncan Campbell, styled Lord Ormelie, was overlooked for the succession ( owing to his " incapacity ") and died childless in 1727.

** Duncan Campbell, Lord Ormelie ( c. 1660 – 1727 )

In 1727, Charles Calvert, 5th Lord Baltimore ( then governor of the Maryland Colony ) awarded a land grant for present day Mount Pleasant to James Holmead.

Lord Orford had no children and the titles became extinct on his death in 1727.

Lord Desart was the younger son of John Cuffe, who represented Thomastown in the Irish House of Commons between 1715 and 1727.

Jean Elliot ( April 1727 – 29 March 1805 ), also known as Jane Elliot, was a Scottish poet, and the third daughter of Sir Gilbert Elliot of Minto, Lord Justice Clerk of Scotland.

He held office under his father-in-law Sir Robert Walpole as a Lord of the Admiralty from 1727 to 1729, as a Lord of the Treasury from 1735 to 1736 and as Chancellor of the Duchy of Lancaster from 1736 to 1743 ( from 1742 to 1743 under the premiership of the The Earl of Wilmington.

He was Member of Parliament for Midlothian from 1722 to 1727, 1727 to 1734 and 1734 – 7 ; He was chief adviser of Lord Ilay's opponents.

He served as Lord of the Bedchamber to King George II from 1727 and, in 1735, he was appointed Master of the Horse.

In 1725 Byng was made a Knight Companion of the Order of the Bath and in 1727, on the accession of George II, he was made First Lord of the Admiralty.

He held the supreme post in the Admiralty Board for over a decade, before being dismissed as First Lord of the Admiralty on 2 August 1727, for opposing Sir Robert Walpole, and also left his office as Lord of the Bedchamber at this time.

* Benedict Leonard Calvert ( 1700 – 1732 ), the proprietary governor of the Maryland colony from 1727 through 1731, appointed by his brother, Charles Calvert, 5th Baron Baltimore.

Benedict Leonard Calvert ( 1700 – 1732 ), Governor of the Maryland colony from 1727 through 1731, appointed by his brother, Charles Calvert, 5th Baron Baltimore.

The first ophthalmic surgeon in Great Britain was John Freke, appointed to the position by the Governors of St Bartholomew's Hospital in 1727, but the establishment of the first dedicated ophthalmic hospital in 1805 ; now called Moorfields Eye Hospital in London, England was a transforming event in modern ophthalmology.

In 1727 he was appointed organist at the church of St. Paul in Paris, ahead of Jean-Philippe Rameau who was also a candidate.

In 1727, Münnich was appointed the Governor of Saint Petersburg city while the Imperial court was temporarily transferred to Moscow by Peter II.

In December 1727 he was appointed vice-principal of the Scots College at Paris, where he died on 28 January 1744.

On the death of John Radcliffe in 1714, Mead became the recognized head of his profession ; he attended Queen Anne on her deathbed, and in 1727 was appointed physician to George II, having previously served him in that capacity when he was prince of Wales.

In 1727, Stair tried, again unsuccessfully, to have Adam appointed Surveyor of the King's Works in Scotland, although the following year he acquired the lesser position of Clerk and Storekeeper of the King's Works in Scotland, under the Master of Works Sir John Anstruther.

The Qing imperial resident in Tibet was introduced in 1727 and most ambasa were appointed from the Manchu Eight Banners, a few were Han Chinese or Mongol.

In 1727, he became librarian of the German national Library in Leuven, in 1734, he was appointed educator of the Bavarian Princes Clemens und Max, sons of Prince Ferdinand Maria.

* Johann Franz Freiherr von Eckher von Kapfing und Liechteneck ( appointed 29 January 1695 ; died 23 February 1727 )

* James Gordon ( succeeded 12 October 1718 – appointed the Vicar Apostolic of Lowland District on 23 July 1727 )

* James Gordon ( appointed 23 July 1727 – died 18 February 1746 )

In 1727 Miranda was appointed " agent to receive and collect the perquisites and rights of Admiralty ," and on June 19, 1727, he was appointed " deputy judge of the Court of Vice-Admiralty "— the first judicial office held by a Jew in the provinces.

In 1727, he was appointed honorary Academician of the Accademia Clementina in Bologna.

In 1727, James Franklin ( brother of Benjamin ) was printing in Newport ; in 1732, he published the first newspaper, the Rhode Island Gazette.

He was born in Arbury, Warwickshire, the son of Sir Richard Newdigate, 3rd Baronet ( who died in 1727 ) and inherited the title 5th Baronet and the estates of Arbury and of Harefield in Middlesex on the early death of his brother in 1734.

* Francesco Giuseppe Casanova ( 1727 – 1803 ), Italian painter, brother of Giacomo Casanova

A highly rated composer was František Xaver Budinský ( 1676 – 1727 ), who appears to have been a Jesuit lay brother and worked in Trnava, Prešov, Košice, Trenčín, and elsewhere in Slovakia.

In 1727, he was returned both for Guildford and Surrey, with the highest majority ever recorded, and elected to serve for Surrey ; his younger brother Richard Onslow replaced him at Guildford in a by-election.

The Baronetcy, of Hawkestone in the County of Shropshire, was created in the Baronetage of Great Britain in 1727 for the first Viscount Hill's grandfather Rowland Hill, with remainder to his cousins Samuel Hill, of Shenstone, Thomas Hill, of Tern ( whose eldest son Noel Hill was created Baron Berwick in 1784 ) and Rowland Hill, brother of Thomas.

In November 1727, Bessler's maid, Anne Rosine Mauersbergerin, ran away from Bessler's household and testified under oath that she had turned the machines manually from an adjoining room, alternating in that job with Bessler's wife, his brother Gottfried, and Bessler himself.

* Abel-François Poisson, marquis de Marigny, ( 1727 – 1781 ), the brother of Madame de Pompadour, at 8, Place Vendôme

Empress Elizabeth of Russia lent her support to the latter faction, partly because she fondly remembered Adolf Frederick's brother, her projected spouse who had died several months before the wedding could take place ( in June 1727 ).

Their eldest daughter, Marie Françoise Julie Filleul ( Château de Longpré, 1751-Paris, 1822 ) married at the Château de Menars in 1767 Abel François Poisson, marquis de Vandières et de Marigny ( 1727 – 1781 ), the brother of Madame de Pompadour ; Adélaïde-Émilie married on 30 January 1779 Alexandre Sébastien de Flahaut de La Billarderie, comte de Flahaut de La Billarderie, a soldier of some reputation, who was many years her senior.