Edward Anthony Jenner, FRS ( 17 May 1749 – 26 January 1823 ) was an English physician and scientist from Berkeley, Gloucestershire, who was the pioneer of smallpox vaccine.

Edward Jenner was born on 17 May 1749 ( 6 May Old Style ) in Berkeley, as the eighth of nine children.

A bio-bibliography of Edward Jenner, 1749 – 1823.

A generation later, Father Le Loutre's War began when Edward Cornwallis arrived to establish Halifax with 13 transports on June 21, 1749.

* 1749 – Edward Rutledge, American statesman ( d. 1800 )

* January 26 – Edward Jenner, English physician and medical researcher ( b. 1749 )

* January 23 – Edward Rutledge, U. S. statesman ( b. 1749 )

The return of Louisbourg to French control by the peace treaty prompted the British to found Halifax in 1749 under Edward Cornwallis.

On July 24, 1749, the town layout as it appears today was surveyed and platted by Washington with the assistance of his chainmen John Lonem and Edward Corder as part of his service to Fairfax.

With the founding of both Halifax ( 1749 ) and Fort Edward, there was an Acadian Exodus that involved an emigration of most of the Acadians from the Municipality of East Hants ( 1750 ) and from West Hants ( Pisiguit ) as well.

Father Le Loutre's War began when Edward Cornwallis arrived to establish Halifax with 13 transports on June 21, 1749.

The war began when Edward Cornwallis arrived to establish Halifax with 13 transports and a sloop of war on June 21, 1749.

Edward Rutledge ( November 23, 1749 – January 23, 1800 ) was an American politician and youngest signer of the United States Declaration of Independence.

He prepared editions, which won the praise of Edward Gibbon, of the Ars poetica and Epistola ad Pisones ( 1749 ), and the Epistola ad Augustum ( 1751 ) of Horace.

Named after Edward Shepherd, tenant at the wheel from 1749 to 1794, when 10 men were employed here.

Harriot married firstly in 1726 Richard Eliot, having nine children including Edward Craggs-Eliot, 1st Baron Eliot and secondly in 1749 to John Hamilton by whom she had a son.

From 1749 – 55, there was massive Acadian migration out of British-occupied mainland Nova Scotia and into French-occupied Ile Saint-Jean ( Prince Edward Island ), Ile Royale ( Cape Breton ) and present-day New Brunswick.

* Edward Moseley, 1735 – 1749

* Edward Jenner FRS ( 1749 – 1823 ), English scientist and the first doctor to introduce and study the smallpox vaccine

Edward Morgan ( d. 1749 ), a native of Llangelynnin, was vicar of St Cadfan's from 1717.

* Edward Jenner ( 1749 – 1823 ), developed the smallpox vaccine

In 1749, British Governor Edward Cornwallis offered payment to New England Rangers for Indian scalps.

Born Edward Hussey, he was the husband of Lady Isabella Montagu, widow of the 2nd Duke of Manchester and daughter of the 2nd Duke of Montagu, and had assumed by Royal Licence the additional surname of Montagu in 1749.

* Edward Rutledge ( 1749 – 1800 ), U. S. politician, signer of the Declaration of Independence ; brother of John Rutledge

On 11 September 1749, Cornwallis wrote to the Board of Trade:

In 1749, Governor Cornwallis again asked the Acadians to take the oath and although he was unsuccessful, he took no drastic action against them.

Father Le Loutre's War began when Edward Cornwallis arrived to establish Halifax with 13 transports on June 21, 1749.

First settled in August 1749 by Captain John Gorham, acting on orders from Governor Edward Cornwallis to establish a military fort named Fort Sackville, Lower Sackville is now one of the fastest growing communities in Nova Scotia, and contains a mix of residential and commercial development in the Sackville River valley, immediately north of the former town of Bedford.

Originally established with the arrival of Edward Cornwallis and the out break of Father Le Loutre's War ( 1749 ), the current fort was built in the Victorian Era as the hub of the historic defence system for the port.

Rochford arrived at Turin on 9 September 1749.

Acadians first arrived at Shediac in 1749 as a result of the Acadian Exodus from peninsular Nova Scotia.

In 1749 he arrived in England to seek support, but eventually fell into debt and was confined in a debtors ' prison in London until 1755.

He traveled back to his home via Naples, Florence and Bologna, and arrived back in Valenciennes in the beginning of March 1749.

Hans Egede's Hope Colony was organized under the auspices of the Bergen Greenland Company prior to its bankruptcy in 1727 ; it was succeeded by the merchant Jacob Severin ( 1733 – 1749 ), the General Trade Company ( Det almindelige Handelskompagni ; 1749 – 1774 ), and finally the Royal Greenland Trading Department ( KGH ; 1776 – 1908 ).

In 1749, Rousseau was paying daily visits to Diderot, who had been thrown into the fortress of Vincennes under a lettre de cachet for opinions in his " Lettre sur les aveugles ," that hinted at materialism, a belief in atoms, and natural selection.

During this time, under the direction of court architects, Joseph Saint-Pierre and Carl von Gontard, numerous courtly buildings and attractions were created: the Margravial Opera House with its richly furnished baroque theatre ( 1744 – 1748 ), the New ' Castle ' and Sun Temple ( 1749 – 1753 ) at the Hermitage, the New Palace with its courtyard garden ( 1754 ff ) to replace the Old Palace which had burned down through the carelessness of the margrave, and the magnificent row of buildings in today's Friedrichstraße.

Zedler also published new works such as the trade lexicon Allgemeine Schatz-Kammer Der Kaufmannschafft ( 1741 – 1743, 4 volumes and 1 supplement volume ), stock exchange laws Corpus Juris Cambialis ( Johann Gottlieb Siegels, 1742, 2 volumes ) and the Historical-Political-Geographical Atlas of the whole world ( 1744 – 1749, 13 volumes ), published under the name of the Leipzig bookseller, Johann Samuel Heinsius the Elder.

The 1749 revival at Covent Garden, under the proper title of Messiah, saw the appearance of two female soloists who would henceforth be closely associated with Handel's music: Giulia Frasi and Caterina Galli.

* an edition of Basilius Faber's Thesaurus eruditionis scholasticae ( 1726 ), afterwards continued under the title Novus linguae et eruditionis Romanae thesaurus ( 1749 )

Burnet graduated from Princeton University in 1749, studied medicine under Dr. Staats in White Plains, New York, and started his practice in Newark.

Reynosa was founded on 14 March 1749 with 297 inhabitants by Carlos Cantú under the command of José de Escandón y Helguera the Count of Sierra Gorda.

Much of Brainerd's influence on future generations can be attributed to the biography compiled by Jonathan Edwards and first published in 1749 under the title of An Account of the Life of the Late Reverend Mr. David Brainerd.

Hester was the sister of Richard Temple, 1st Viscount Cobham, whose title she inherited under a special remainder in 1749 ; in the same year ( or maybe in 1751 ), her husband being long dead, she was created 1st Countess Temple.

In 1749, under Louis XV, a new tax based on the " dixième ", the " vingtième " ( or " one-twentieth "), was enacted to reduce the royal deficit, and this tax continued through the ancien régime.

His collections reached home in safety, and five years after his death his notes were published by Linnaeus under the title Iter Palæstinum, Eller Resa til Heliga Landet, Förrättad Ifrån år 1749 til 1752, which was translated into French and German in 1762 and into English in 1766 ( as Voyages and Travels in the Levant, in the Years 1749, 50, 51, 52 ).

In 1800, he spent a year at the mining academy in Freiberg, Saxony, where he studied under the noted geologist Abraham Gottlob Werner ( 1749 or 1750 – 1817 ).

It briefly passed into the possession of the French from 1746 to 1749, but was restored to Great Britain under the Treaty of Aix-la-Chapelle, which ended the War of the Austrian Succession.

At the time of his death in 1749, Shahu made the Peshwas his successors under such conditions.

In May 1748 he was appointed by the archbishop-elector Francis George von Schönborn as his auxiliary bishop, being consecrated at Mainz, in February 1749, under the title of bishop of Myriophiri in partibus.

In September 1746, Fort St George was taken by the French who ruled Madras as a part of French India until 1749 when Madras was handed back to the British under the terms of the Treaty of Aix-la-Chappelle.

It was once again remodelled in 1749, under the direction of Father Teodósio Ferreira de Melo.

The Music for the Royal Fireworks ( HWV 351 ) is a wind band suite composed by George Frideric Handel in 1749 under contract of George II of Great Britain for the fireworks in London's Green Park on 27 April 1749.

Admiral of the Fleet Sir John Norris ( 1670 or 1671 – 13 or 14 June 1749 ) was a British naval officer of the 17th and 18th centuries, who served as Commander-in-Chief of the Royal Navy under George II.