The spelling and names in both the 1609 – 1610 Douay Old Testament ( and in the 1582 Rheims New Testament ) and the 1749 revision by Bishop Challoner ( the edition currently in print used by many Catholics, and the source of traditional Catholic spellings in English ) and in the Septuagint ( an ancient translation of the Old Testament in to Greek, which is widely used by the Eastern Orthodox instead of the Masoretic text ) differ from those spellings and names used in modern editions which are derived from the Hebrew Masoretic text.

Edward Anthony Jenner, FRS ( 17 May 1749 – 26 January 1823 ) was an English physician and scientist from Berkeley, Gloucestershire, who was the pioneer of smallpox vaccine.

A Life of Gregory by the Vartabed Matthew was published in the Armenian language at Venice in 1749 and was translated into English by the Rev.

Thomas Cannon wrote what may be the earliest published defence of homosexuality in English, Ancient and Modern Pederasty Investigated and Exemplify'd ( 1749 ).

In 15 – 16th-century French and English depictions of relationships between women ( Lives of Gallant Ladies by Brantôme in 1665, John Cleland's 1749 erotica Memoirs of a Woman of Pleasure, L ' Espion Anglais by various authors in 1778 ), writers ' attitudes spanned from amused tolerance to arousal, whereupon a male character would participate to complete the act.

* 1675 – Richard Temple, 1st Viscount Cobham, English soldier and politician ( d. 1749 )

In the English-speaking world, the Douay-Rheims Bible — translated from the Latin Vulgate by expatriate recusants in Rheims, France in 1582 ( New Testament ) and in Douai, France in 1609 ( Old Testament )— which was revised by Bishop Richard Challoner in 1749 – 1752 ( the 1750 revision is that which is printed today ), was, until the prompting for " new translations from the original languages " given by Pope Pius XII in the 1942 encyclical letter Divino afflante spiritu and the Second Vatican Council, the translation used by most Catholics ( after Divino afflante spiritu, translations multiplied in the Catholic world, just as they multiplied in the Protestant world around the same time beginning with the Revised Standard Version, with various other translations being used around the world for English-language liturgies, ranging from the New American Bible, the Jerusalem Bible, the Revised Standard Version Second Catholic Edition, and the upcoming English Standard Version Catholic lectionary ).

Two men independently developed the octant around 1730: John Hadley ( 1682 – 1744 ), an English mathematician, and Thomas Godfrey ( 1704 – 1749 ), a glazier in Philadelphia.

* January 26 – Edward Jenner, English physician and medical researcher ( b. 1749 )

* April 3 – Mark Catesby, English naturalist ( d. 1749 )

* March 18 – Matthew Decker, English merchant and writer ( d. 1749 )

* October 24 – Richard Temple, 1st Viscount Cobham, English soldier and politician ( d. 1749 )

Accidental crosses were noticed as far back as 1749 in the southern English colonies of North America.

Derived from the ancient Greek word kharaktêr, the English word dates from the Restoration, although it became widely used after its appearance in Tom Jones in 1749.

The Radcliffe Camera ( Camera, meaning " room " in Italian ) ( colloquially, " Rad Cam "; " Radder " in 1930s slang ) is a building in Oxford, England, designed by James Gibbs in the English Palladian style and built in 1737 – 1749 to house the Radcliffe Science Library.

Another edition of the Lineae tertii ordinis was published in Paris in 1797 ; another edition of the Methodus differentialis in London in 1764 ; and a translation of the latter into English by Halliday in London in 1749.

In 1749, he represented the somewhat disorderly English troops on their March of the Guards to Finchley ( formerly located in Thomas Coram Foundation for Children, now Foundling Museum ).

Other major 18th century English novelists are Samuel Richardson ( 1689-1761 ), author of the epistolary novels Pamela, or Virtue Rewarded ( 1740 ) and Clarissa ( 1747-8 ); Henry Fielding ( 1707 – 54 ), who wrote Joseph Andrews ( 1742 ) and The History of Tom Jones, a Foundling ( 1749 ); Laurence Sterne ( 1713 – 68 ) who published Tristram Shandy in parts between 1759 and 1767 ; Oliver Goldsmith (? 1730-74 ) author of The Vicar of Wakefield ( 1766 ); Tobias Smollett ( 1721 – 71 ) a Scottish novelist best known for his comic picaresque novels, such as The Adventures of Peregrine Pickle ( 1751 ) and The Expedition of Humphry Clinker ( 1771 ), who influenced Charles Dickens ; and Fanny Burney ( 1752-1840 ), whose novels " were enjoyed and admired by Jane Austen ," wrote Evelina ( 1778 ), Cecilia ( 1782 ) and Camilla ( 1796 ).

First published on 28 February 1749, Tom Jones is among the earliest English prose works describable as a novel.

* Cater Rand ( 1749 – 1825 ), English surveyor

This aspect of the novel, plus Cleland's presumed offence at Westminster School, lack of intimate friends, and his unmarried status have aided conjecture that he was homosexual, as has his bitter falling out with friend Thomas Cannon, author of the pamphlet Ancient and Modern Pederasty Investigated and Exemplify'd ( 1749 ), the earliest surviving published defence of homosexuality in English ( Gladfelder ).

* November-Alethea Lewis, English novelist ( born 1749 )

* Fanny Hill ( 1749 ) by John Cleland – depicts mutual flagellation, between Fanny and an English client.

The Universal etymological English dictionary of 1749 gives the town as " Chester upon Street " ( and describes it as " a Village in the Bishoprick of Durham ").

Settled later by colonists from Dover and Somersworth, the town was granted in 1749 by John Mason.

Granted by the Masonian Proprietors in 1749 as Cochecho Township, New Durham was settled in 1750 almost entirely by colonists from Durham.

Modern-day Hidalgo was first settled by Spanish colonists led by José de Escandón in about 1749.

For protection, the colonists built several forts, including one near Bear Inlet, which was erected in 1749 and has since disappeared.

Upon the death of Sir George Downing, 3rd Baronet in 1749, the wealth left by his grandfather, Sir George Downing, who served both Cromwell and Charles II and built 10 Downing Street ( a door formerly from Number 10 is in use in the college ), was applied by his will.

Less noted is his published call in 1749 for the roofing-over of Perrault's classical colonnaded east front of the Palais du Louvre and the clearing away of the ramshackle structures, both those that had been built against it, in order to form a proper Place du Louvre, and those in the centre of the Cour Carré itself Sections of the palace were in danger of collapse, scarcely touched by royal indifference after 1678 ; work did begin in 1755 to clear the facade of the Louvre, overseen by the architect Jacques-Germain Soufflot and Marigny, supervisor of the Bâtiments du Roi.

Augusta Stone Church built in 1749

It replaced a structure built in 1749, but that was not the first mill at Hoxne, since a mill is shown on Kirby's map of Suffolk, dated 1736, and two mills are mentioned in the Domesday Book of 1086, although this probably meant that there were two sets of stones.

" Barnett concludes that ' more than twenty years ' before 1769 roughly corresponds to Sommer's appointment as minister, and that sometime between 1743 and 1749, the first church in Brunswick was built.

The earliest European settlement in the area was a French mission, built by Abbé Picquet in 1749.

James Witherspoon built the home in 1749 when the house was located six miles outside of town near where the Battle of the Lower Bridge took place.

The land on which the town is built was originally conveyed from Thomas Lord Fairfax to George Mason in 1749.

In 1749, Zinzendorf leased Lindsey House, a large manor in Chelsea built on the estate of Sir Thomas More to be a headquarters for work in England.

Fort Christiansværn built in 1749 and other buildings are maintained by the National Park Service as the Christiansted National Historic Site.

This story is false: the bridge was built of oak in 1749 by James Essex the Younger ( 1722 – 1784 ) to the design of the master carpenter William Etheridge ( 1709 – 1776 ), 22 years after Newton died.

The church was built in 1749 by Jakob and Hans Ulrich Grubenmann, and renovated in 1832 / 1833 by Gebhard Moosbrugger.

The building collapsed in 1749 and the present church of St. Michael's was built in 1758.

Great St. Mary's church was originally built in the 13th century ( although a church on the site existed in Saxon times ) and includes a Tudor tower containing a clock bell ( 1664 ) and eight ringing bells, the oldest of which dates from 1749.

He died on 24 March 1773 at Chesterfield House, Westminster, the grand London townhouse he had built in about 1749.

Built in 1749, the Melingriffith Tinplate Works just across the River Taff from Radyr was built on or near the site of an old corn mill that had operated as far back as the late 12th century.

The bridge was designed by William Etheridge, and built by James Essex in 1749.

Amalienborg is the centrepiece of Frederiksstaden, a district that was built by King Frederick V to commemorate in 1748 the tercentenary of the Oldenburg family's ascent to the throne of Denmark, and in 1749 the tercentenary of the coronation of Christian I of Denmark.

* was an 80-gun first rate built in 1694, then rebuilt and relaunched in 1722, and rebuilt for a third time to a 66-gun third rate in 1749.

* Studley Royal Park, Yorkshire, the stables ( c. 1729 ) built after his death by Roger Morris ( 1695 – 1749 )

The town hall was built between 1749 and 1754 to a design by John Wood the Elder replacing an earlier town hall nearby.

In 1749 the city's first General Infirmary was built on the site, followed by the Seaman's Hospital in 1752, a dispensary in 1778, and a lunatic asylum in 1789.