* Great Irish Famine ( 1845 – 1851 )

Revised versions of " Irish Countess " and " Schalken " were reprinted in Le Fanu's first collection of short stories, the very rare Ghost Stories and Tales of Mystery ( 1851 ).

* February 22 – George Francis FitzGerald, Irish mathematician ( born 1851 )

The Times is the first newspaper to have borne that name, lending it to numerous other papers around the world, including The Times of India ( 1838 ), The Straits Times ( 1845 ), The New York Times ( 1851 ), The Irish Times ( 1859 ), the Los Angeles Times ( 1881 ), The Seattle Times ( 1891 ), The Daily Times ( Malawi ) ( 1900 ), The Canberra Times ( 1926 ), The Times ( Malta ) ( 1935 ) and The Times of Israel ( Israel ) ( 2012 ).

The chimney-piece, which was exhibited at the Medieval Court of the Great Exhibition of 1851, was also designed by Pugin ( and Myers ) but was originally intended for Horstead Place in Sussex, it was rejected because it was too elaborate and subsequently bought for Lismore-the Barchard family emblems later replaced with the present Irish inscription Cead Mille Failte: a hundred thousand welcomes.

St. Bridget's was established in 1851 by early Irish settlers in the area.

In 1851, Irish and English pioneers moved to the area and called the place Wolf River.

* Lady Lucy Anne FitzGerald ( 1771 – 1851 ), who took part in the Irish Rebellion of 1798.

* August 17-Richard Lalor Sheil, Irish politician, author and orator ( died 1851 )

Earlier work by the Irish physician Robert Bentley Todd ( 1847 ), Ernest Horn, and Moritz Heinrich Romberg ( 1851 ) had described Tabes dorsalis and noted atrophy of the spinal cord, but in an important paper, Gull also stressed the involvement of the posterior column in paraplegia with sensory ataxia.

* February 22-George FitzGerald ( born 1851 ), Irish mathematician.

John Dillon ( 4 September 1851 – 4 August 1927 ) was an Irish politician from Dublin, who served as a Member of Parliament ( MP ) for over 35 years and was the last leader of the Irish Parliamentary Party.

* William Edward Wilson ( astronomer ) ( 1851 – 1908 ), Irish astronomer

George Francis FitzGerald ( 3 August 1851 – 22 February 1901 ) was an Irish professor of " natural and experimental philosophy " ( i. e., physics ) at Trinity College in Dublin, Ireland, during the last quarter of the 19th century.

George Noble Plunkett or Count Plunkett (; 3 December 1851 – 12 March 1948 ) was a biographer and Irish nationalist, and father of Joseph Mary Plunkett, one of the leaders of the Easter Rising of 1916.

The Cork, Bandon and South Coast Railway ( CB & SCR ) was one of the major Irish railways ; incorporated 1845, the first section opened 1851.

* Waterford and Tramore Railway 12 km ( 7. 25 mi ); incorporated 1851, opened 1853 ; four locomotives, 32 other vehicles ; unique in being the only line to remain unconnected to the rest of the Irish railway.

Bradford has experienced significant levels of immigration throughout the 19th and 20th centurys. In the 1840s Bradford's population was significantly increased by migrants from Ireland, particularly rural Mayo and Sligo, and by 1851 around 18, 000 people of Irish origin resided in the town, representing around 10 % of the population, the largest proportion in Yorkshire.

* James Campbell, 1st Baron Glenavy ( 1851 – 1931 ), Irish Solicitor-General, Attorney-General and Lord Chancellor

James Henry Mussen Campbell, 1st Baron Glenavy PC ( 4 April 1851 – 22 March 1931 ) was an Irish lawyer, politician in the Parliament of the United Kingdom of Great Britain and Ireland and later in the Oireachtas of the Irish Free State.

He was a Tory politician and sat as an Irish Representative Peer between 1838 and 1851.

* Edward Joseph Kennedy ( born 1851 ), Irish nationalist politician, Member of Parliament for South Sligo

* 1851 – Walter Reed, American physician and biologist ( d. 1902 )

* November 23 – Walter Reed, American army physician ( b. 1851 )

Kilmer was born 6 December 1886 in New Brunswick, New Jersey, the fourth and youngest child, of Annie Ellen Kilburn ( 1849 – 1932 ), a minor writer and composer, and Dr. Frederick Barnett Kilmer ( 1851 – 1934 ), a physician and analytical chemist employed by the Johnson and Johnson Company and inventor of the company's baby powder.

* Daniel Newnan ( 1780 – 1851 ), Politician and physician

* John Kidd ( 1775 – 1851 ), physician, chemist and geologist

* Theodore Dyke Acland ( 1851 – 1931 ), surgeon and physician

David Macbeth Moir ( 5 January 1798 – 6 July 1851 ) was a Scottish physician and writer.

John Kidd ( 10 September 1775 – 7 September 1851 ) was an English physician, chemist and geologist.

Major Walter Reed, M. D., ( September 13, 1851 – November 22, 1902 ) was a U. S. Army physician who in 1900 led the team that postulated and confirmed the theory that yellow fever is transmitted by a particular mosquito species, rather than by direct contact.

Joel Roberts Poinsett ( March 2, 1779 – December 12, 1851 ) was an American physician, botanist and statesman.

Dr. George II, Bruhn, a German physician, in the month of January, 1851, ( i. e. before Mr. Hargraves ' discovery at Summerhill ) started from Melbourne to explore " the mineral resources of this colony.

* Jonas Basanavičius ( 1851 – 1927 ), physician, scientist, patriot, activist, signer of the Act of Independence of Lithuania

* William Whitla ( 1851 – 1953 )-Politician and physician.

A physician and professor of medicine, Barreda studied in Paris under Auguste Comte between 1847 and 1851 and is widely credited with introducing positivism in Mexico.

Jacques-Arsène d ' Arsonval ( June 8, 1851 – December 13, 1940 ) was born in La Porcherie and was a French physician, physicist, and inventor of the moving-coil galvanometer and the thermocouple ammeter.

In 1851, a process for extraction of kerosene from bituminous shale was patented by Canadian physician and geologist Abraham Pineo Gesner.

Jean Guillaume Auguste Lugol ( 18 August 1786 – 16 September 1851 ) was a French physician.

Samuel George Morton ( 1799 – 1851 ) was an American physician and natural scientist.

Drapetomania was a supposed mental illness described by American physician Samuel A. Cartwright in 1851 that caused black slaves to flee captivity.

He originally trained to be a physician in Halle and Leipzig, and received his medical doctorate from Berlin in 1851.

Hodges was originally a physician, but served as both the mayor and coroner of Los Angeles from 1850 to 1851.

In psychiatry, dysaethesia aethiopica was an alleged mental illness described by American physician Samuel A. Cartwright in 1851, which proposed a theory for the cause of laziness among slaves.

* David Macbeth Moir ( 1798 – 1851 ), Scottish physician and writer