The fact that most of the early post-translational modifications found were concentrated within the tail extensions that protrude from the nucleosome core lead to two main theories regarding the mechanism of histone modification.

In fact, a slight modification of the decompressor to run at block sizes larger than 4x4 pixels produces a method of stretching images without causing the blockiness or blurriness of traditional linear resampling algorithms.

Upon analyzing of the results of the study it was concluded that the anterior cingulate cortex is indeed involved in the modification of cognitive tasks that require attention based on the fact that there was a change in the basal firing rate of neurons in that region during simulation of such tasks.

Of major concern is the fact that the polycyclic aromatic hydrocarbons found in tobacco smoke are potent inducers of CYP1A2 so that smokers may require significant modification of medication dosage.

The most notable example of the politicization of this topic was the modification of the National Cancer Institute ( NCI ) fact sheet by the George W. Bush administration from concluding no link to a more ambiguous assessment regarding the abortion-breast cancer hypothesis, despite the NCI's scientifically-based assessment to the contrary.

) This was so successful that application software and operating system software above the LIC layer that were compiled on the original S / 38 run without modification and without recompilation on the latest AS / 400 systems, despite the fact that the underlying hardware has been changed dramatically ; at least three different types of processors have been in use.

This was necessitated by the fact that 4 mm holes in the Soviet sockets could not accept 4. 8 mm Shuko pins without modification.

The fourth season finale revealed that, in fact, a genetic modification procedure known as Project Helix was used to create a double of Irina, and it is this woman whom Jack shot dead.

For certain applications, the slippage inherent in automatic transmissions can be advantageous ; for instance, in drag racing, the automatic transmission allows the car to be stopped with the engine at a high rpm ( the " stall speed ") to allow for a very quick launch when the brakes are released ; in fact, a common modification is to increase the stall speed of the transmission.

Considering the modification of the drepanosaur neck for the purposes of snap-action predation, it becomes more likely that superficial similarities in the cervicals of both taxa are in fact only convergent with Aves.

A phenomenon looks like regular shader to the user, and in fact may be a regular shader, but generally it will contain a link to a shader DAG, which may include the introduction or modification of geometry, introduction of lenses, environments, and compile options.

Reasons included the fact that larger SSGN and SSBN submarines now in the Fleet had more available space and could accommodate female Officers with little or no modification.

Of these the first is that the theory as stated, e. g., by Alexander Bain, lays far too much stress on the mere connexion of elements hitherto entirely separate ; whereas, in fact, every new mental state or synthesis consists in the development or modification of a pre-existing state or psychic whole.

In fact, he argues, artifacts and sites undergo, respectively post-use and post-occupational modification by diverse formation processes.

This was despite the fact that the 1784 creation of the earldom held by the Townshend family was then still extant ( hence the territorial designation " of Holkham ").

Proposals were made that the Townshend tax also be waived, but North opposed this idea, citing the fact that those revenues were used to pay the salaries of crown officials in the colonies.

In fact this debut was something of a family affair as her nieces Emma and Aminta Townshend were backup singers.

Russell also recalled that Pete Townshend initially balked at Russell's wish to have The Who performing behind Elton in the sequence ( they did not perform the audio here ), and also objected to wearing the pound-note suits ( which were in fact stitched together from novelty pound-note teatowels ).

Townshend, in fact, was the initiating force behind the album.

The conservative nature of these changes underlines the fact that Protestantism was by no means universally popular – a fact that the queen herself recognized: her revived Act of Supremacy, giving her the ambiguous title of Supreme Governor passed without difficulty, but the Act of Uniformity 1559 giving statutory force to the Prayer Book, passed through the House of Lords by only three votes.

The problem comes from the fact that before the Copyright Act of 1976 the number of years a work was copyrighted in the U. S. was based on publication rather than life of the author plus a certain number of years and that it was good for only 28 years.

It received its name from the fact that through an Act of Parliament, it could only be dissolved with the agreement of the members and those members did not agree to its dissolution until after the English Civil War and at the end of Interregnum in 1660.

This measure substantially increased the population of Canada west of the St. Lawrence-Ottawa River confluence during this period, a fact recognized by the Constitutional Act of 1791, which split Quebec into the Canadas: Upper Canada southwest of the St. Lawrence-Ottawa River confluence, and Lower Canada east of it.

In fact the locals lost their entire rights through the Code de l ' indigénat Act.

Most Democrats and Republicans in the Senate — in fact four-fifths of the members of his own party — voted for the Civil Rights Act, but not Senator Goldwater.

A reform of the King's title following an Imperial Conference decision and given effect by the Royal and Parliamentary Titles Act 1927, changed the King's royal title so that it took account of the fact that there was no longer a United Kingdom of Great Britain and Ireland.

Furthermore, the Chinese Exclusion Act did not address the problems that whites were facing ; in fact, the Chinese were quickly and eagerly replaced by the Japanese, who assumed the role of the Chinese in society.

In fact, some gang leaders were stashing liquor months before the Volstead Act was enforced.

In recognition of that fact, on November 30, 2004 President George W. Bush signed HR 1446, the " California Mission Preservation Act ", into law.

The Commission also had little power over networks ; in fact, the Radio Act of 1927 made almost no mention of the radio networks ( notably NBC and, a bit later CBS ) that were in the process of dominating radio.

Daniel and Honigmann cite Act 2, Scene 1, where Hortensio is omitted from the scene where Tranio ( as Lucentio ) and Gremio bid for Bianca, despite the fact that everyone knows Hortensio is also a suitor.

Most notably, Bassett's Toronto Northmen were forced to find a new home after the Canadian government threatened to ban any American football team from competing with the Canadian Football League ( despite the fact that the Toronto Rifles of the Continental Football League had played in Toronto just seven years prior ); though the Canadian Football Act never passed, the mere threat of it prompted Bassett to move the team to Memphis, where they became the Memphis Southmen, but were generally referred to by fans, local media, and even some official team materials as the " Grizzlies ".

The PRC views the Taiwan Relations Act as " an unwarranted intrusion by the United States into the internal affairs of China ," despite the fact that the post WWII Treaty of San Francisco did not award the territorial sovereignty of Taiwan to China.

In the courtroom of Kenesaw Mountain Landis, the future Commissioner of Baseball who perpetuated the baseball color line until his death, Johnson was convicted by an all-white jury in June 1913, despite the fact that the incidents used to convict him took place prior to passage of the Mann Act.

The use of the generic " he " was in fact enforced by an Act of Parliament and, despite its putative inclusiveness, has been used to deny women's entry into professions and schools.

Another concern is the fact that most webmail service providers are based in the U. S. A. and are therefore subject to the Patriot Act, which means that U. S. authorities can demand that a company must hand over whatever information it has about a user, without necessarily letting the user know, regardless of the country in which the user lives or where the information is stored.

These features were retained in the design despite the fact that by the time the station opened the 1921 Railway Act had been passed which spelt the end of the L & SWR as an independent concern.

The fact that enforcement of the federal Pure Food and Drug Act of 1906 was given to the Bureau of Chemistry rather than placed in the Department of Commerce or the Department of the Interior is a tribute to the scientific qualifications which the Bureau of Chemistry brought to the study of food and drug adulteration and misbranding.

Besides the chapel, it contains the Sängersaal ( Hall of the Minstrels ), which is in fact Wagner's setting for Act II of Tannhäuser and the Festsaal ( the Feast or Festival Hall ), both of which contain fine frescoes by Moritz von Schwind with the theme of the minstrels ' contest in the Sängersaal and frescoes of the triumphs of Christianity in the Festsaal.

However, formally, this still remains the standard method, a fact that is recited by the wording of the Letters Patent for the appointment of the Royal Commissioners, and by the wording of the Letters Patent for the granting of the Royal Assent in writing under the 1967 Act ("... And forasmuch as We cannot at this time be present in the Higher House of Our said Parliament being the accustomed place for giving Our Royal Assent ...").

The Act was intended to update the name of the United Kingdom as well as the King's title to reflect the fact that most of the island of Ireland had left the United Kingdom.