Their recreational appeal exists mainly due to their anticholinergic properties, that induce anxiolysis and, in some cases such as diphenhydramine, chlorpheniramine, and orphenadrine, a characteristic euphoria at moderate doses.

The disease is treated either with oral vancomycin or with intravenous metronidazole. Oral metronidazole at doses of 500 mg three times a day for 10 to 14 days can be used for mild to moderate cases of C. difficile.

The deleterious side-effects occur either under high dose or when moderate doses interact with potentiators such as azithromycin.

Leary says this circuit enables telepathic communication and is activated by low-to-moderate doses of LSD ( 50-150 µg ), moderate doses of peyote, and psilocybin mushrooms.

Clinical depression itself was reported to increase the occurrence of seizures two-to-sevenfold compared with the general population ; in this light, the above statistics could indicate that low to moderate doses of antidepressants, including bupropion, may actually have an anti-convulsive action.

Energy drinks, by contrast, are intended to improve mental energy by stimulating the central nervous system, usually with moderate to large doses of caffeine or other stimulants, though many also supply physical energy in the form of sugar.

# Once lipid-lowering therapy is initiated, patients with type 2 diabetes mellitus should be taking at least moderate doses of a statin ( the accompanying evidence report states " simvastatin, 40 mg / d ; pravastatin, 40 mg / d ; lovastatin, 40 mg / d ; atorvastatin, 20 mg / d ; or an equivalent dose of another statin ").

At moderate doses (> 150 mg / day ), it acts on serotonergic and noradrenergic systems, whereas at high doses (> 300 mg / day ), it also affects dopaminergic neurotransmission.

If ADHD is associated with sleep disturbances, low to moderate doses of clonidine can be taken at bedtime.

Though they are generally ineffective antidepressants, as most are short-acting, the rapid onset of alcohol and sedative / hypnotics softens rigid defenses and, in low to moderate doses, provides relief from depressive affect and anxiety.

Up to 75 % of patients with schizophrenia have increased signs and symptoms of their psychosis upon challenge with moderate doses of methylphenidate or amphetamine or other dopamine-like compounds, all given at doses at which control normal volunteers do not have any psychologically disturbing effects.

Pilocarpine is given in moderate doses ( about 2 mg ) to induce emesis in cats who have ingested foreign plants, foods, or drugs.

At moderate doses (> 150 mg / day ), it acts on serotonergic and noradrenergic systems, whereas at high doses (> 300 mg / day ), it also affects dopaminergic neurotransmission.

These tests were performed on patients with mild to moderate dementia, and the doses were 800-2400 mg orally twice a day for one to six months.

Systemic delivery into many cells in adult organisms can be accomplished by using covalent conjugates of Morpholino oligos with cell-penetrating peptides, and, while toxicity has been associated with moderate doses of the peptide conjugates, they have been used in vivo for effective oligo delivery at doses below those causing observed toxicity.

A clinical trial showed significant effect for a Rhodiola extract in doses of 340 – 680 mg per day in male and female patients from 18 to 70 years old with mild to moderate depression.

No side effects were demonstrated at these doses in the treatment of mild to moderate depression.

Extensive research has demonstrated that moderate doses of MDMA taken a limited number of times are sufficiently safe for human consumption.

: For every substance, small doses stimulate, moderate doses inhibit, large doses kill.

Even though alcoholism can increase the risk of liver cancer, studies have shown that a moderate consumption of alcohol ( 1 serving / day for women and 2 servings / day for men ) does not affect diabetes Type II greatly.

Colour can range from deep gold to light amber with a large, creamy, persistent white head, and moderate to moderately high carbonation, while alcohol content ranges from 6. 3 % to 7. 4 % by volume.

Some Protestant Christian denominations prohibit the drinking of alcohol based upon Biblical passages which condemn drunkenness ( such as Proverbs 23: 21, Isaiah 28: 1, Habakkuk 2: 15 ), but others allow moderate use of alcohol.

Jehovah's Witnesses allow moderate alcohol consumption amongst its members.

Alcohol consumption tends to raise HDL levels, and moderate alcohol consumption is associated with lower cardiovascular and all-cause mortality.

Mormons adhere to the Word of Wisdom, a health law or code that is interpreted as prohibiting the consumption of tobacco, alcohol, coffee and tea, while encouraging the use of wholesome herbs, grains, fruits, and a moderate consumption of meat.

In 1980, the World Health Organization ( WHO ) classified it as a drug of abuse that can produce mild to moderate psychological dependence ( less than tobacco or alcohol ), although the WHO does not consider khat to be seriously addictive.

In 1980, the WHO classified the plant as a drug of abuse that can produce mild to moderate psychological dependence ( less than tobacco or alcohol ), although the WHO does not consider khat to be seriously addictive.

Based on Cochrane's review the American Academy of Family Physicians ( AAFP ) recommends use of kava for patients with mild to moderate anxiety disorders who are not using alcohol or taking other medicines metabolized by the liver, but who wish to use “ natural ” remedies.

Patients should decrease fluid intake before bedtime, moderate the consumption of alcohol and caffeine-containing products, and follow timed voiding schedules.

As the disease worsened and the medication greatly altered Turner's looks, along with excess alcohol consumption that Turner said she used to kill her physical pain, her once promising film career as a leading lady took a nose dive and Turner was seen in fewer and fewer blockbusters — though Turner also blamed her age, stating that " when I was forty the roles started slowing down, I started getting offers to play mothers and grandmothers ..." She appeared in the low-budget House of Cards, experienced moderate success with John Waters's black comedy Serial Mom, and had supporting roles in A Simple Wish, The Real Blonde, and Sofia Coppola's acclaimed The Virgin Suicides.

For example, optimists smoke less, are more physically active, consume more fruit, vegetables and whole-grain bread, and consume more moderate amounts of alcohol.

Beers termed brown ale include sweet, low alcohol beers such as Manns Original Brown Ale, medium strength amber beers of moderate bitterness such as Newcastle Brown Ale, and malty but hoppy beers such as Sierra Nevada Brown Ale.

A “ session beer ”, such as a session bitter, is a beer that has a moderate or relative low alcohol content.

While full bodied recioto and Amarone styles reach alcohol levels of 15-16 %, most Valpolicellas have more moderate alcohol levels around 11 %.

It has been noted that every individual has an individual sensitivity level to alcohol or sedative hypnotic drugs, and what one person can tolerate without ill health, may cause another to suffer very ill health, and even moderate drinking can cause rebound anxiety syndrome and sleep disorders.

This latter explanation is in spite of evidence linking moderate alcohol consumption to reduced incidence of coronary disease.

Pratt is notorious for being unable to tolerate even moderate amounts of alcohol.

He dislikes intoxicants and drugs because they cloud the mind ; only on very rare occasions has he ever relaxed enough to imbibe even moderate amounts of alcohol, and then only in very secure surroundings.

The beers typically have a moderate alcohol content of 4 to 5 % ABV.

Mild hyponatremia ups the risk of fracture in elderly patients because hyponatremia has been shown to cause subtle neurologic impairment that affects gait and attention, similar to that of moderate alcohol intake.

* Byetta, a Type II Diabetes drug, will cause moderate nausea and loss of appetite

# Mitahara ( म ि तह ा र ): moderate appetite, neither eating too much nor too little ; nor consuming meat, fish, shellfish, fowl or eggs.

I tell you I am well looked after and at a charge so moderate that I am almost ashamed of my appetite.