Initially using the sea slug as an experimental model but later working with mice, he established that the formation of memories is a consequence of short and long-term changes in the biochemistry of nerve cellsGreengard was recognized for his discovery that dopamine and a number of other transmitters can alter the functional state of neuronal proteins, and also that such changes could be reversed by subsequent environmental signals.

Initially he experimented with individual cells in series, each cell being a wine goblet filled with brine into which the two dissimilar electrodes were dipped.

Initially all tape cells are marked with 0.

Initially a simple ball of cells, the blastula soon transforms into a cone-shaped echinopluteus larva.

" Initially designed to house 320 inmates ( 20 in solitary cells and 300 in two large communal blocks ), Evin expanded to hold more than 1500 prisoners ( including 100 solitary cells for the most important political prisoners ) by 1977.

Initially called Puck, it was designed to conduct experiments to test the technologies necessary for communication satellites, such as solar cells, telemetry and power systems.

Initially discovered in the cells that make up the retina of the eye, CNG channels have been found in many different cell types across both the Animal and the Plant Kingdoms.

Initially this high resolution low-loss mode was used to examine bacteriophage and blood cells in collaboration with researchers at NYU, and at the Veteran ’ s Administration Hospital in New Jersey however, the bulk of his work was devoted to using the microscopes as tools to scribe things using the lithography techniques that were becoming familiar for making silicon chips.

Initially, the endoderm consists of flattened cells, which subsequently become columnar.

Initially, much of the cell-space, the universe of the cellular automaton, is " blank ," consisting of cells in the ground state U. When given an input excitation from a neighboring ordinary-or special transmission state, the cell in the ground state becomes " sensitised ," transitioning through a series of states before finally " resting " at a quiescent transmission or confluent state.

Initially the studies were aimed at replacing cells that were damaged by disease with cells grown ex-vivo, however the field evolved and cells are instead used as secretors of factors that can ameliorate or change the course of disease.

Initially, the IEEE Foundation's role was to accept and administer donations for the IEEE Awards program, but donations increased beyond what was necessary for this purpose, and the scope was broadened.

Initially the team made numerous trades and increased their payroll in an effort to assemble a better team.

Initially the impact of the loss of jobs was masked by increased employment with Fort Dix and McGuire Air Force Base, especially during the period of the Vietnam War.

Initially he supported increased autonomy within the Russian Empire, in opposition to the Social Democrats in the coalition-Senate, who in vain strived for more far-reaching autonomy ; but after the Bolshevik October Revolution Paasikivi championed full independence — albeit in the form of constitutional monarchy.

Initially support was high in Utah, especially in the Beaver County area ; although opposition increased dramatically following a statement of disapproval by the leaders of The Church of Jesus Christ of Latter-day Saints.

Initially a small, informal group, Das Kleeblatt increased it influence in the Wiener Camera-Klub through its international connections, and several other organizations promoting pictorialism were created in other cities throughout the region.

Initially the competing electronic calculators were no cheaper nor smaller than the ANITA, but Bell Punch responded by opening a new research and development building on its Uxbridge site, and electronics research was increased for the calculators and the other Bell Punch products.

Initially, attendance increased.

Initially, average attendance had increased over previous seasons at Memorial Stadium.

Initially during increased exertion, muscle glycogen is broken down to produce glucose, which undergoes glycolysis producing pyruvate which then reacts with oxygen ( Krebs cycle ) to produce carbon dioxide and water and releasing energy.

Initially small and carried only on main and fore masts, they gradually increased in size and importance until by the middle of the 17th century and were the principal and largest sails of the ship, the first sails to be set and the last to be taken in.

Initially Zumtobel Group was targeting customers mainly from Europe and North America but in recent years operations in middle east has increased.

Initially, the NFL rule stated that a team may wear their third jersey only once a year, however, after one year this restriction was increased to twice a year.

Initially almost unemployed due to the lack of education and contacts which a university education would have provided, his business increased thanks to his friendships with John Dunning, who, overwhelmed with cases, allowed Kenyon to work many, and Lord Thurlow who secured for him the Chief Justiceship of Chester in 1780.

Initially hindered by political instability and turmoil on Madagascar during the mid-1970s, field studies resumed in the 1980s and have greatly increased our understanding of these primates.

Initially the constitution provided that the Executive Council would consist of between five and seven ministers ( not including its president ) but under a constitutional amendment adopted in 1927 this maximum limit was increased to twelve.

Initially, the tape was 60 meters ( 197 feet ) or 90 meters ( 295 ft .) long, although advancements in materials technology have allowed the length to be increased significantly in successive versions.

Initially bipedal, as their size increased they evolved to become graviportal quadrupeds ( like elephants ).

Initially the base versions of the R3 and R4 came with a thick C-pillar behind each of the rear doors although for a 400 franc supplement over the price of the basic R4 buyers could specify a body with the C-pillar filled by a third side window which increased the weight but which soon became standard for all R4s.

Initially it worked, but later an increased dosage transformed Algar physically, giving him a distorted body that is eel-like.

Initially, the medical school curriculum was three years in length, unlike most medical schools, but it later was increased to the usual four years in 1979.

Initially the activities were confined to providing legal aid to women, but gradually these activities increased to including legal awareness, education, protection from exploitation, legal research, counseling and providing legal assistance as well.

Initially 500 were to be made for the US Market, BMW later increased production to as many as 1, 370 units for the US and Canadian markets, although the generally accepted figure is 1, 244 units sold.

Initially it had room for only 10 patients, but it has continually increased its bed count throughout the years to 235 beds, in addition to expanding its services.

Initially the victims were killed with gas vans or by firing squad, but these methods proved impracticable for an operation of this scale.

Initially lacking a synchronizer, the Royal Flying Corps relied on pusher aircraft such as the Vickers F. B. 5 Gunbus and the Airco D. H. 2 in which the propeller was behind the pilot, and therefore out of the way of forward firing guns.

Initially the soldier claimed the shooting occurred during an armed firefight between Israeli soldiers and Palestinian militants but the prosecuted soldier later admitted firing at him " as a deterrent ".

Initially heavy bronze or brass bodies were used, and the wires soldered, but later much lighter copper vessels were used, and the wire glued on before firing.

Initially its value was fixed, so that 1 SDR = 1 US dollar, but this was abandoned in favor of a currency basket after the 1973 collapse of the Bretton Woods system of fixed exchange rates.

Initially, she is incensed that a member of the powerful Galactic Federation's elite Observers ( which it is revealed that Mizuho has the honor of being its youngest member ) would stoop to marry such an evident primitive ( conveniently overlooking the fact that she is ostensibly the product of just such a union, claiming that the only time that she had ever seen Mizuho cry was when their father died ; the implication of wildly different growth rates between alien and human are suggested here, as Maho is much younger appearing than Mizuho and Mizuho had stated that she could barely recall her father's appearance ).

Initially, the need arose because of the high sickness and death rates of European sailors on India-bound ships, and their frequent desertions in India, which left ships short of crew for the return voyage.