Knowing that Kensuke Mitsuda had studied and described the “ Mitsuda Reaction ” ( Lepromin reaction ), He lobbied for the publication of an international journal, and finally Hayashi F, wrote the first article on the Mitsuda reaction in its first issue He opposed the prevalent practice in Japan of segregation of leprosy patients into sanatoriums.

Knowing she was severely ill, in 1878 Dorsey made over her will, leaving Beauvoir and her financial assets to Jefferson Davis and, in the case of his death, to his only surviving child, Winnie Davis.

Knowing her death was imminent, May Belle Mitchell wrote her daughter a brief letter and advised her:

" Knowing " means that the actor was aware or practically certain that the death would result.

Knowing that Willow is too strong to defeat, he tricks her into draining him of his white magics, which brings him near death.

* Knowing the time of death ( 預知時至 ): some prepare by bathing and reciting the name of the Buddha Amitabha.

Knowing features Nicolas Cage as a teacher who discovers a set of numbers that are actually the dates, death tolls and locations of disaster events both in the past and the future, while 2012, based on the supposed doomsday prediction by the Mayans, sees various disasters bring the world to an end.

Knowing his death would come before his son Toyotomi Hideyori came of age, Hideyoshi named five regents — one of whom was Hidetada's father, Ieyasu — to rule in his son's place.

Following the death of Ian Tomlinson, Street-Porter dedicated her editor-at-large column in the Independent on Sunday to painting a picture of Tomlinson as a " troubled man with quite a few problems ":" Knowing that he was an alcoholic is critical to understanding his sense of disorientation and his attitude towards the police, which might on first viewing of the video footage, seem a bit stroppy.

Knowing he will not come back alive, Johnny releases him and watches, with the authorities, as Bodhi goes to his death.

Knowing its poor legal grounds, Joseph negotiated a secret agreement with Charles Theodore shortly after Max Joseph's death.

Knowing he'd never be able to keep the team together for long, Doctor Octopus quickly formulated a battle plan in which each individual member of the Sinister Six would battle Spider-Man in a carefully chosen location, giving each of them personal glory and Spider-Man an early death.

Knowing that either a Tellarite or an Andorian death will forever halt peace talks in the region and that Graal, not being a warrior at all, would surely be the looser, Archer announces to Shran that he will fight him as Graal's replacement.

Knowing she failed to rescue Nejiru from a slow death, Doris was overridden with both guilt and concern as she is the only person outside the Gaou family to remember Nejiru.

Knowing that the Abbot of Holyrood was on the point of death, Robert, according to George Buchanan, wagered a large sum with James V that he would not present him to the first vacant benefice, while the King, quite well aware of what he referred to, accepted and won the wager.

Knowing of his death, a guilt-stricken White acknowledged that his previous prejudices against Colt, whom he had considered an amateurish detective afraid to sully his hands, were harsh, and that White could have helped him more.

Knowing her death is imminent, she plunges the Spear of Destiny into the ship's hull, to prevent Estacado from claiming the treasure.

Knowing that it would not be possible to conduct proper elections of the Patriarch upon his death, Patriarch Tikhon made a will where he appointed three candidates, one of whom would assume the leadership of the Church after Tikhon's own death.

Knowing and willful refusal to present oneself for and submit to registration as ordered is punishable by a maximum penalty of up to 5 years in Federal prison and / or a fine of US $ 250, 000, although there have been no prosecutions of draft registration resisters since 1987.

Knowing that the federal government would pay " top dollar ", the employees of a contractor in the Indiana Territory reportedly named Robert Hoosier asked their boss if they could go work for this higher wage in the neighboring state of Ohio.

Knowing that Christine had musical talent, they asked her to join.

Knowing he could handle the direction of the actors but would be at a loss with the action scenes, he asked David Lean to supervise the filming of those.

Knowing that lobbyists hostile to the suggestions would likely try to encourage legislative gridlock until the constitutionally-mandated end of the sixty day session, Chandler asked his allies in the General Assembly to adjourn after thirty-nine days and allow him to call a special legislative session that would not be time-limited and could only entertain the agenda he specified.

Knowing that officers of such youth would not be taken seriously, he asked General Naguib to assume leadership of the movement.

Knowing this, Cunningham made his way to the Bernabeu in the off season, and asked if they would like to sign him, thus getting the ball rolling with the negotiations at Ron Atkinson's house.

Knowing he could attain the location for very little, and being a savvy producer, Bender telephoned all the screenwriters he knew and asked if they had any screenplays that took place in a bank.

Knowing the allied force was low on grain, Li Li asked Fan Chou to pursuit and wipe the enemy out, but was refused by the former because of his friendship with Han Sui.

Knowing that r-pronunciation was a prestigious trait, many of the lower-class speakers in another Labov study — in which speakers were asked to read from word lists — added-r to words that did not have an r at all.

Knowing she came from the Liverpool area, he asked after her at the Golden Cross at Charing Cross and was told that a girl of her description had boarded the coach for Chester in the north at 7. 00 p. m. Mr Shetley took a postchaise with a Mr Lowe, and overtook the coach at St Albans.

Knowing what she did was wrong, Lizzie asked Phillip to forgive her and pointed out that she had taken good care of Emma.

Knowing the allied force was low on grain, Li Li asked Fan to pursuit and wipe the enemy out, but was refused by the former because of his friendship with Han.

Knowing about Jake's skill at the table, Macha and the three Eddies asked him to fill in the spot.

Knowing Judy cannot put up a good fight, Bobby points his hand at Beasely and encases him in a block of ice.

Knowing nothing about Rachel's theft, Jacob told Laban that whoever stole them should die and stood aside to let him search.

Knowing the Earth's velocity and the aberration angle, this enabled him to estimate the speed of light.

Knowing Luthor's role in the Army's attack against him, Superman confronts him and tells him that Metropolis doesn't belong to him: " You don't own us.

Knowing that Crusader forces were massed upon the frontier to intercept him, he took the desert route across the Sinai Peninsula to Ailah at the head of the Gulf of Aqaba.

Knowing that he is nearing the end of his life, Moses appoints Joshua his successor, bequeathing to him the mantle of leadership.

THX is consigned to another region of limbo, this one populated by a collection of other prisoners, including SEN. Knowing that THX filed the complaint against him, SEN nevertheless rallies him to join his undescribed cause.

Knowing of his design, the gods met him in full battle-array.

Knowing he cannot withstand Cuhullin, Finn asks his wife Oona to help him.

Knowing that such speculation, combined with Congressional grants of land sections to veterans of the Revolution, could result in a lucrative opportunity, Ebenezer Zane in 1796 petitioned the US Congress to grant him a contract to blaze a trail through Ohio, from Wheeling, West Virginia, to Limestone, Kentucky, ( near modern Maysville, Kentucky ) a distance of.

Knowing Gandhi's deep anguish regarding proposals of partition, Patel engaged him in frank discussion in private meetings over the perceived practical unworkability of any Congress-League coalition, the rising violence and the threat of civil war.

Knowing that the castle is too strong to take by force, Robin decides to use guile, visiting the bishop and " persuading " him to include Robin and his men, in disguise, in his entourage.

Knowing that choosing any of them would bring him the hatred of the other two, Zeus did not want to take part in the decision.

Knowing she is dying, Bernadette sends for Abbé Peyramale ( who in reality died a few years before Bernadette ) and tells him of her feelings of unworthiness and her concern that she will never see the lady again.

Knowing such a step could forever deprive him of power, Hitler decided to carry out his pact with the Reichswehr to suppress the SA.

Knowing that Thorfinn has more power and can easily overtake him, Brusi visits King Olaf to try to gain his support in helping him maintain his control over his share.

Knowing Sonic and Tails will try to track him down, and realizing he can use the Master Emerald to power the ship, Dr. Robotnik dupes Knuckles into believing Sonic is trying to steal his Emerald.

Knowing that Dior had created the sketches that morning and that the young man could not have seen them, de Brunhoff sent him to Dior, who hired him on the spot.

Knowing he is dying, Taylor ( after Zaius refuses to help him ) decides to stop the violence by detonating the bomb.