Lactoferrin ( LF ), also known as lactotransferrin ( LTF ), is a multifunctional protein of the transferrin family.

Lactoferrin is also present in secondary granules of PMN and is secreted by some acinar cells.

Lactoferrin also suppresses virus replication after the virus penetrated into the cell.

Lactoferrin acts, mostly in vitro, on a wide range of human and animal viruses based on DNA and RNA genomes, including the herpes simplex virus 1 and 2, cytomegalovirus, HIV, hepatitis C virus, hantaviruses, rotaviruses, poliovirus type 1, human respiratory syncytial virus and murine leukemia viruses.

Lactoferrin seems to destroy the cell wall and bind the plasma membrane of C. albicans.

Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions.

Lactoferrin can be purified from milk or produced recombinantly.

Lactoferrin is one of the components of the immune system of the body ; it has antimicrobial activity ( bacteriocide, fungicide ) and is part of the innate defense, mainly at mucoses.

Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.

Lactoferrin is one of the transferrin proteins that transfer iron to the cells and control the level of free iron in the blood and external secretions.

Lactoferrin belongs to the basic proteins, its isoelectric point is 8. 7.

Lactoferrin forms reddish complex with iron ; its affinity for iron is 300 times higher than that of transferrin.

Lactoferrin tends to polymerize both in vitro and in vivo, especially at high concentrations.

Lactoferrin belongs to the innate immune system.

Lactoferrin binds to lipopolysaccharide of bacterial walls, and the oxidized iron part of the lactoferrin oxidizes bacteria via formation of peroxides.

Lactoferrin not only disrupts the membrane, but even penetrates into the cell.

Lactoferrin binds to the same lipoproteins thereby repelling the virus particles.

Lactoferrin and lactoferricin inhibit in vitro growth of Trichophyton mentagrophytes, which are responsible for several skin diseases such as ringworm.

Lactoferrin has shown to have positive effects on bone turnover.

Lactoferrin hydrolyzes RNA and exhibits the properties of pyrimidine-specific secretory ribonucleases.

Lactoferrin, a component of innate immunity, prevents bacterial biofilm development.

Lactoferrin with hypothiocyanite has been granted orphan drug status by the EMEA and the FDA.

That fall he submitted to Professor Baker the first acts and outlines of the following acts of several plays, six of them, according to some of his associates, and he also worked on a play that he first called Niggertown, the material for which he had collected during the summer at home.

To achieve this destiny, acts as well as words are needed -- not only acts that lead to physical strength but also acts that lead to strength based on right doing and respect.

The freeway with narrowly spaced interchanges concentrates and mitigates the access problem, but it also acts inevitably as an artificial, isolating boundary.

Men also perform more altruistic acts in the early stages of a romantic relationship or simply when in the presence of an attractive woman.

Although they " were expecting to see activity in the brain's reward centers ", based on the idea that " people perform altruistic acts because they feel good about it ", what they found was that " another part of the brain was also involved, and it was quite sensitive to the difference between doing something for personal gain and doing it for someone else's gain ".

It is important to note that, while research supports the idea that altruistic acts bring about happiness, it has also been found to work in the opposite direction — that happier people are also kinder.

Additionally, while generous acts make people feel good about themselves, it is also important for people to appreciate the kindness they receive from others.

That was so because it not only was proof of excessive pride, but also resulted in violent acts by or to those involved.

They also maintained the acts of the Plebeian Council ( popular assembly ), the " plebiscites ".

* Stimulation of the posterior pituitary to release vasopressin ( antidiuretic hormone, ADH ) also acts on the kidneys to increase water retention.

Some also block or partially block serotonin receptors ( particularly 5HT < sub > 2A, C </ sub > and 5HT < sub > 1A </ sub > receptors ): ranging from risperidone, which acts overwhelmingly on serotonin receptors, to amisulpride, which has no serotonergic activity.

Amputation has also been used as a tactic in war and acts of terrorism ; it may also occur as a war injury.

Whether hand laid or built in a mould, FRP boats usually have an outer coating of gelcoat which is a thin solid colored layer of polyester resin that adds no structural strength, but does create a smooth surface which can be buffed to a high shine and also acts as a protective layer against sunlight.

There are also a number of acts both in the US ( Johnny Rogers, John Mueller ) and UK ( Marc Robinson, Spencer J etc.

Furthermore, the director's contract of service will usually entitle him to compensation if he is removed, and may often include a generous " golden parachute " which also acts as a deterrent to removal.

However, in instances an individual director may still bind the company by his acts by virtue of his ostensible authority ( see also: the rule in Turquand's Case ).

He was also known as The Originator because of his key role in the transition from the blues to rock, influencing a host of acts, including Buddy Holly, Jimi Hendrix, The Rolling Stones, The Velvet Underground, The Who, The Yardbirds, Eric Clapton, Elvis Presley, The Beatles, and George Michael, among others.

Celibacy excludes not only libidinous acts, but also sinful thoughts or desires of the flesh.

Such acts of recognition of a saint were authoritative, in the strict sense, only for the diocese or ecclesiastical province for which they were issued, but with the spread of the fame of a saint, were often accepted elsewhere also.

They were constituted as the conservators of public morality ; they were not simply to prevent crime or particular acts of immorality, but rather to maintain the traditional Roman character, ethics, and habits ( mos majorum )— regimen morum also encompassed this protection of traditional ways, which was called in the times of the empire cura (" supervision ") or praefectura (" command ").