Large-scale commercial hunting of Indian crocodilians for their skin began towards the end of the 19th century, and by the 1970s, crocodile populations were severely depleted.

Large-scale composting systems are used by many urban areas around the world.

Large-scale production resulted from the development of deep-tank fermentation by chemical engineer Margaret Hutchinson Rousseau.

Large-scale quantum computers could be able to solve certain problems much faster than any classical computer by using the best currently known algorithms, like integer factorization using Shor's algorithm or the simulation of quantum many-body systems.

Large-scale wildebeest migration is quite likely a consequence of decisions being made by individuals at multiple spatial scales, involving a balance of food abundance, food quality, local density of other wildebeest, social interactions, surface water, perceived predation risk, and culturally ( or possibly genetically ) learned routes and ranges.

Large-scale pineapple cultivation by U. S. companies began in the early 1900s on Hawaii.

Large-scale ( hundreds of miles ) lateral movement along the fault was first proposed in a 1953 paper by geologists Mason Hill and Thomas Dibblee.

Large-scale compositions by Finzi include the cantata Dies natalis for solo voice and string orchestra, and his concertos for cello and clarinet.

Large-scale hydrography is usually undertaken by national or international organizations which sponsor data collection through precise surveys and publish charts and descriptive material for navigational purposes.

Large-scale development of Kowloon began in the early 20th century, with the construction of the Kowloon-Canton Railway and the Kowloon Wharf, but due to Kowloon's close proximity to Kai Tak Airport, building construction was limited by flight paths.

Large-scale pieces such as De Staat ( 1972 – 76 ), for example, are influenced by the energy of the big band music of Count Basie and Stan Kenton and the repetitive procedures of Steve Reich, both combined with bright, clashing dissonances.

* Large-scale replica of the Santa María, one of the ships sailed by Christopher Columbus.

Large-scale pre-planning and extensive project scheduling are replaced by smaller experiments, which can be rapidly adapted as new improvements are suggested.

Large-scale terrorist operations have been prepared by the KGB and GRU against the United States, Canada and Europe, according to the Mitrokhin Archive, GRU defectors Victor Suvorov and Stanislav Lunev, and former SVR officer Kouzminov.

Large-scale interviews conducted since 1972 by the GSS of people in monogamous relationships reveals that the number of men admitting to extra marital affairs is 12 percent and for women, 7 percent.

Large-scale excavations were conducted at various times between 1930 and 1937 by Homer Thompson, in collaboration first with K. Kourouniotes and later with Robert Scranton.

Large-scale anti-criminal operations carried out by the Georgian Special Forces as of March 2004 () resulted in significant improvement of the situation.

Large-scale resemblances in plotting — the missing prince, the ruler and his heir who fall in love with the same woman — could be explained through derivation from common sources ; but these larger-scale elements are supported by specific lines and passages that occur in both plays.

Large-scale property developments along the West Rail were originally planned to generate new passenger demand but were delayed by government policy.

Large-scale sound reinforcement systems are designed, installed, and operated by audio engineers and audio technicians.

Large-scale systems are able to be calculated by this method.

Walters, " Large-scale management experiments and learning by doing ", in: Ecology.

Large-scale residential development is in progress, however, at Brockworth, on the other side of the M5 motorway, linked from Abbeymead Avenue by Lobleys Drive.

Large-scale expropriations of land in the Galilee have generally been avoided by Israeli governments since the 1980s.

Large-scale commercial growing often selects for different characteristics that hobbyist growers might want, such as resistance to root rot when overwatered, ability to be forced into budding early, ease of rooting or other propagation, and saleability.

Large-scale projects to support willow as an energy crop are already at commercial scale in Sweden, and in other countries, others are being developed through initiatives such as the Willow Biomass Project in the US and the Energy Coppice Project in the UK.

Large-scale commercial development is concentrated along the Interstate 494 corridor.

Large-scale commercial development began with Colony Square, the first mixed-use development in the Southeast, which was built between 1969 and 1973.

Large-scale gene transfer has also occurred between the ancestors of eukaryotic cells and prokaryotes, during the acquisition of chloroplasts and mitochondria.

Large-scale land clearing for agriculture has damaged habitats for native flora and fauna.

Large-scale emigration abroad as well as to Northern Italy, which began to diminish only in the 1970s, has had a lasting effect on the demographic situation in the region.

Large-scale West Indian immigration over the last century has also decreased the number of Black Bermudians who are multi-racial, and hardened attitudes.

Large-scale emigration has caused many of the smaller towns and villages to lose over 60 % of their population, while only a small number of larger towns have recorded significant gains.

Large-scale gene transfer has also occurred between the ancestors of eukaryotic cells and prokaryotes, during the acquisition of chloroplasts and mitochondria.

Large-scale captive breeding of Tiger salamanders has not been accomplished, for unknown reasons.

Large-scale habitat destruction and fragmentation has undoubtedly been important, and may well be the major factor, although there is some evidence that suggests the birds clearly favours agricultural land with patches of remnant native vegetation over intact areas of vegetation.

Large-scale wall-paintings were apparently much less regarded, relatively crudely executed, and rarely mentioned in contemporary sources ; they were probably seen as a cheap but inferior substitute for mosaic, which in this period must be treated as a fine art, though in recent centuries contemporary production has tended to be seen as decorative.

Large-scale restoration work carried out in the early 20th century with money from the returned Americanos has converted it into a spectacular building with Byzantine, Moorish, Renaissance and Modernist influences.

Large-scale tree mortality has been reported in only one instance, in northern Ontario, Canada, after two outbreak cycles in the early and late 1990s occurred back-to-back, resulting in more than six consecutive years of aspen defoliation in some areas.

Large-scale demolition has reduced the number of residents in the area, and replaced them with restaurants and large, Hong Kong-style shopping malls.

Large-scale population movements from rural to urban areas of Latin America and to other regions of the world have increased the geographic distribution of Chagas disease, and cases have been noted in many countries, particularly in Europe.

Large-scale rat control programs have been taken to maintain a steady level of the invasive predators in order to conserve the native species in New Zealand such as kokako and mohua.

Large-scale projects with significant financial demands and substantial human resource requirements have been avoided since they will not be realistic or sustainable.

Large-scale frequency oscillations and electrical rhythms have also been shown to regulate TC activity for long periods of time, as is evident during the sleep cycle.