Larger molecules are transported by transmembrane carrier proteins, such as permeases that change their conformation as the molecules are carried through, for example glucose or amino acids.

Larger molecules ( often proteins, DNA, or polysaccharides ) that have dimensions significantly greater than the pore diameter are retained inside the dialysis bag.

Larger proteins, even in smaller amounts, usually result in better engagement of antigen presenting antigen processing cells for a satisfactory immune response.

Larger molecules can only traverse the outer membrane by active transport through mitochondrial membrane transport proteins, and mitochondrial preproteins are imported through specialised translocase complexes.

Larger organisms require a biofilm to attach, which is composed of proteins, polysaccharides, and microorganisms.

Larger, extracellularly-derived AGE proteins cannot pass through the basement membrane of the renal corpuscle and must first be degraded into AGE-peptides and AGE free adducts.

Larger molecules ( such as proteins, or polysaccharides ) that have dimensions significantly greater than the pore diameter are retained inside the dialysis bag.

Larger earthquakes can generate very large shear loads on structures.

Larger cruise missiles can carry either a conventional or a nuclear warhead, while smaller ones carry only conventional warheads.

Larger sets such as double-twenty-one can theoretically exist but are rarely seen in retail stores, as identifying the number of pips on each domino becomes difficult, and a double-twenty-one set would have 253 pieces, far more than is normally necessary for most domino games even with eight players.

Larger containers such as plastic storage containers ( Tupperware or similar ) or ammunition boxes can also contain items for trading, usually toys or trinkets of little value.

Larger gates can be used for a whole building, such as a castle or fortified town, or the actual doors that block entry through the gatehouse.

Larger penguins can dive deep in case of need.

Larger networks have complex topologies that can change rapidly, making the manual construction of routing tables unfeasible.

Larger DS3 signals can also have their DS0 signals switched in Digital Network Unit SONET ( DNUS ) units, without demultiplexing them into DS1.

Larger species can reach over long and weigh well over.

Larger models, which can store over 200 litres ( 53 US gallons ), are often hooked up to compressed air, utilizing the Venturi effect to produce a partial vacuum.

Larger and faster models can improve access to commercial buildings ( NZ, commercial ).

Larger bamboos and Arundo donax have stout culms that can be used in a manner similar to timber, and grass roots stabilize the sod of sod houses.

Larger cities often have city courts which hear traffic offenses and violations of city ordinances ; in some states, such as New York State, these courts also have broader jurisdictions as inferior jurisdiction courts and can handle small civil claims and misdemeanor casees.

Larger animals may regard guinea pigs as prey, though some ( such as dogs ) can be trained to accept them.

Larger SAMs may be deployed in fixed launchers, but can be towed / re-deployed at will.

Larger craft can reach as far upstream as Leibsch, although the upper reaches are relatively shallow and are generally only used by leisure craft.

Larger doses can bring about respiratory depression, slurred speech, headache, and photophobia ( a symptom of excessive sensitivity to light ).

Larger airports usually have several runways in different directions, so that one can be selected that is most nearly aligned with the wind.

Larger amounts than 10 grams is considered trafficking and can lead to a maximum jail sentence of 5 years.

Larger wafers allow improvements in manufacturing efficiency, as more chips can be fabricated on each wafer, so there has been a steady drive to increase silicon wafer sizes.

Larger fans rotating more slowly, which produce less noise than smaller, faster fans with the same airflow, can be used.

Larger communities often have walk-in clinics where people with medical problems that would not be considered serious enough to warrant an emergency department visit can be seen.

Larger land-based SAM's can be deployed from fixed installations or mobile launchers.

Larger SAMs may be deployed in fixed launchers, but can be towed / re-deployed at will.

Larger particles cannot enter into as many pores.

Larger fish, such as rainbow and brown trout, prefer cooler, clear water where springbranch canyon tributaries enter the river.

Larger newspapers, traditionally associated with higher-quality journalism, are often called broadsheets, and this designation often remains in common usage even if the newspaper moves to printing on smaller pages, as many have in recent years.

Larger vessels were still built, as command ships, but they were more useful only if they could definitely get close to an enemy, rather than in a battle involving chasing or manoeuvring.

Larger tablets and staves may have been read without turning, if the reader were able to read upside-down.

Larger ( 100 to 140 liters ) free-ride boards are capable of planing at wind speeds as low as 12 knots if rigged with an adequate, well-tuned sail in the six to eight square meter range.

Larger planes will have no problems with the equipment but smaller aircraft will have problems communicating to each other if it lacks an essential component.

Larger Assembly Halls or Convention Centers of Jehovah's Witnesses, or any rented arena or stadium used for larger gatherings of Jehovah's Witnesses are also regarded ' as a large Kingdom Hall '; undignified behavior is considered inappropriate during their religious events, even if the facility is an entertainment venue.

Larger VR environments, covering a greater internal volume in greater detail, are cost-prohibitive even though VR worlds are computed selectively for inhabitants, reducing redundancy and extraneous objects and places to the minimum details required to provide a convincing experience to those inhabitants ; for example, a mirror not being looked at would be reduced to a reflection value, with details being " filled in " as necessary if its owner were to turn their model-of-a-head towards it.

* Larger benefits under some programs if married, including:

Larger hemlocks that are infected have large relatively high root systems that can bring other trees down if one falls.

Larger amounts of endotoxins can be mobilized if Gram-negative bacteria are killed or destroyed by detergents.

Larger objects ( such as vases ) described as shakudō may be mislabeled, especially if the glossy blue-black color is not evident.

Larger ( approximately ) aquariums are much more stable and water changes may not need to take place if the nitrogen cycle has fully established itself in the tank, although this is a controversial statement among aquarists.

Larger sand grains can be used to overcome this problem, but if significant amounts of large solids are in the feed they need to be removed upstream of the sand bed filter by a process such as settling.

; Latency issues: Larger CMSs can experience latency if hardware infrastructure is not up to date, if databases are not being utilized correctly, and if web cache files that have to be reloaded every time data is updated grow large.