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Page "Homeobox protein NANOG" ¶ 14
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Loss and function
* Loss function, in statistics, a function representing the cost associated with an event
* Loss of immune system function
Loss of function mutations in SLC2A9 and SLC22A12 cause hereditary hypouricaemia by reducing urate absorption and unopposed urate secretion.
Loss of mental function is a common complication of bypass surgery, and should influence procedure cost benefit considerations.
* Loss of muscle function or paralysis of the lower legs
Loss of the high ( spatial ) frequency content causes blurring and loss of sharpness ( see discussion related to Point spread function ).
Loss of right ventricular function is a strong predictor of death.
Loss of motor function results in dorsiflexion, contractures of the toes, loss of the interosseous muscle function and leads to contraction of the digits, so called hammer toes.
Loss of dopamine neurons in the substantia nigra is one of the main pathological features of Parkinson's disease, leading to a marked reduction in dopamine function in this pathway.
# Redirect Loss function
Loss of heterozygosity ( LOH ) in a cell is the loss of normal function of one allele of a gene in which the other allele was already inactivated.
Loss of function mutations in this channel may lead to long QT syndrome ( LQT2 ), while gain of function mutations may lead to short QT syndrome.
Loss or gain of AgRP function may result in inadequate adaptive behavioural responses to environmental events, such as stress, and may potentially contribute to the development of eating disorders.
Loss of function of LH receptors can cause male pseudohermaphroditism.
Loss of function for any reason results in an inability to close the eye, necessitating eye drops at the minimum to removal of the eye in extreme cases.

Loss and causes
Loss of consciousness may occur as the result of traumatic brain injury, brain hypoxia ( e. g., due to a brain infarction or cardiac arrest ), severe poisoning with drugs that depress the activity of the central nervous system ( e. g., alcohol and other hypnotic or sedative drugs ), severe fatigue, and other causes.
* Loss Prevention Bulletin The Seveso Disaster: An appraisal of its causes and circumstances, Marshall, V. C., LPB Issue 104, April 1992, IChemE, UK
Hypoxia first causes a greyout ( a dimming of the vision ), also called brownout, followed by tunnel vision and ultimately complete loss of vision ' blackout ' followed by g-induced Loss Of Consciousness or ' g-LOC '.
Loss of aeration also causes important changes in lung mechanical properties.
Loss of PTHrP or its receptor causes the mammary bud cell fate to change back into epidermis.
Loss aversion, therefore, cannot wholly explain the status quo bias, with other potential causes including regret avoidance, transaction costs and psychological commitment.
Loss of capping proteins causes telomere shortening and inappropriate joining by NHEJ, producing dicentric chromosomes which are then pulled apart during mitosis.
Also traumatic causes can lead to Acute Vision Loss.
Loss of neurons in the substantia nigra causes Parkinson's disease, while loss of immune cells impairs the immune system.
Loss of the rubber feet or foot causes the aluminum stile to make contact with the ground, and if a hard surface like concrete or tiling, a skid mark shows how and why the ladder slipped.

Loss and cells
If the traffic on a virtual circuit is exceeding its traffic contract, as determined by the GCRA, the network can either drop the cells or mark the Cell Loss Priority ( CLP ) bit ( to identify a cell as potentially redundant ).
The focus of the Space Tissue Loss – B ( STL-B ) experiment was direct video observation of cells in culture through the use of a video microscope imaging system with the objective of demonstrating near real-time interactive operations to detect and induce cellular responses.
Figure 3 shows the reference algorithm for SCR and PCR control for both Cell Loss Priority ( CLP ) values 1 ( low ) and 0 ( high ) cell flows, i. e. where the cells with both priority values are treated the same.
Loss of heterozygosity can be identified in cancers by noting the presence of heterozygosity at a genetic locus in an organism's germline DNA, and the absence of heterozygosity at that locus in the cancer cells.

Loss and into
In the song " Power and Glory " from Lou Reed's 1992 album Magic and Loss, Reed recalls the experience of seeing his friend dying of cancer and makes reference to the myth, " I saw isotopes introduced into his lungs / trying to stop the cancerous spread / And it made me think of Leda and The Swan / and gold being made from lead "
Loss of " prime " is usually due to ingestion of air into the pump.
The Loss of Sadness: How Psychiatry Transformed Normal Sorrow into Depressive Disorder.
Loss is minimized industrially by spraying into taller towers.
* Loss of a community's small-town feel: Proposals that might result in new people moving into the community, such as a plan to build many new houses, are often claimed to change the community's character.
The album received praise from Metal Maniacs for being, "... another confident step in turning Noumena into Finland ’ s biggest new export .” Earlier the same year they released the EP " Triumph and Loss " which was only made available online.
For research into safety, the Highway Loss Data Institute takes into account a combination of both vehicle size and other vehicle features with all passenger cars that do not fit the definition of either " sports " or " luxury ", are classified on the basis of both vehicle length and wheelbase.
He writes: “ The Ancients in All Towns were for having some intricate Ways and turn again Streets or loops, without any Passage through them, that if an Enemy comes into them, he may be at a Loss, and be in Confusion and Suspense ; or if he pushes on daringly, may be easily destroyed ”.
The album is split into three main parts, " Loss ", " Denial ", and " The Three Metaphors ", bookended by " Tongue " and " Demons Dance Alone ", and broken up by various untitled transitional instrumentals.
* Allan Horwitz and Jerome Wakefield, The Loss of Sadness: How Psychiatry has Transformed Normal Sadness into Depressive Disorder ( Oxford University Press, 2007 )
Loss of consortium has been brought into the law as a cause of action by civil codes, for example, in Maine or into the common law by action of justices.
Loss of GULO activity in the primate order occurred about 63 million years ago, at about the time it split into the suborders haplorrhini ( which lost the enzyme activity ) and the more primitive strepsirrhini ( which retained it ).
* Intellectual Property Loss – When entering into a contract, a company is divulging their formulas or technologies.

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