* The primary technical reference work on this topic is Nanosystems: Molecular Machinery, Manufacturing, and Computation, an in-depth, physics-based analysis of a particular class of potential nanomachines and molecular manufacturing systems, with extensive analyses of their feasibility and performance.

Drexler's 1992 book, Nanosystems: molecular machinery, manufacturing, and computation is technical treatment of similar material.

The feasibility of the basic technologies analyzed in Nanosystems has been the subject of a formal scientific review by U. S. National Academy of Sciences, and has also been the focus of extensive debate on the internet and in the popular press.

The feasibility of Drexler's proposals largely depends, therefore, on whether designs like those in Nanosystems could be built in the absence of a universal assembler to build them and would work as described.

They also claim that much of the other low-level chemistry in Nanosystems requires extensive further work, and that Drexler's higher-level designs therefore rest on speculative foundations.

“ Hybrid PNA / DNA Nanosystems .” In 1st International Conference on Nanoscale / Molecular Mechanics ( N-M2-I ), Outrigger Wailea Resort, Maui, Hawaii.

His 1992 technical book on advanced nanotechnologies Nanosystems: Molecular Machinery, Manufacturing, and Computation describes manufacturing systems that are desktop-scale factories with specialized machines in fixed locations and conveyor belts to move parts from place to place.

Nanosystems addresses chemical, thermodynamic, and other constraints on nanotechnology and manufacturing.

In 1992, Drexler published Nanosystems: Molecular Machinery, Manufacturing, and Computation, a detailed proposal for synthesizing stiff covalent structures using a table-top factory.

* Nanosystems: Molecular Machinery, Manufacturing and Computation index and sample chapters

A typical nanofactory would fit in a desktop box, in the vision of K. Eric Drexler published in Nanosystems: Molecular Machinery, Manufacturing and Computation ( 1992 ), a notable work of " exploratory engineering ".

In 2006, U. S. National Academy of Sciences released the report of a study of molecular manufacturing as part of a longer report, A Matter of Size: Triennial Review of the National Nanotechnology Initiative The study committee reviewed the technical content of Nanosystems, and in its conclusion states that no current theoretical analysis can be considered definitive regarding several questions of potential system performance, and that optimal paths for implementing high-performance systems cannot be predicted with confidence.

In 2006, U. S. National Academy of Sciences released the report of a study of molecular manufacturing as part of a longer report, A Matter of Size: Triennial Review of the National Nanotechnology Initiative The study committee reviewed the technical content of Nanosystems, and in its conclusion states that no current theoretical analysis can be considered definitive regarding several questions of potential system performance, and that optimal paths for implementing high-performance systems cannot be predicted with confidence.

Arlen is one of the few ( possibly the only ) composer Mercer has been able to work with so closely, for they held their meetings in Arlen's study.

In spite of the armistice negotiated by Amadee two years earlier, the war between Bishop Guillaume of Lausanne and Louis of Savoy was still going on, and although little is known about it, that little proves that it was yet another phase of the struggle against French expansion and was closely interwoven with the larger conflict.

There is, of course, nothing new about dystopias, for they belong to a literary tradition which, including also the closely related satiric utopias, stretches from at least as far back as the eighteenth century and Swift's Gulliver's Travels to the twentieth century and Zamiatin's We, Capek's War With The Newts, Huxley's Brave New World, E. M. Forster's `` The Machine Stops '', C. S. Lewis's That Hideous Strength, and Orwell's Nineteen Eighty-Four, and which in science fiction is represented before the present deluge as early as Wells's trilogy, The Time Machine, `` A Story Of The Days To Come '', and When The Sleeper Wakes, and as recently as Jack Williamson's `` With Folded Hands '' ( 1947 ), the classic story of men replaced by their own robots.

The theme of The Walnut Trees Of Altenburg is most closely related to its immediate predecessor in Malraux's array of novels: Man's Hope ( 1937 ).

Lawrence Ferlenghetti and Bruce Lippincott have concentrated on writing a new poetry for reading with jazz that is very closely related to both the musical forms of jazz, and the vocabulary of the musician.

This covered, wooden bridge is so closely identified with the first action in the early morning of June 3, 1861, and with subsequent troop movements of both armies in the Philippi area that it has become a part and parcel of the war story.

Although the standard deviation values on which spread of the lines is based are relatively larger for those centers which begin to ossify early ( Table 1 ), there are considerable differences in this value between centers having the closely timed Onsets.

The nuclei of these fibers, as is shown in Figures 3 and 4, showed remarkable proliferation and were closely approximated, forming a chainlike structure at either the center or the periphery of the fiber.

But even in relatively primitive laboratory animals such as the rat, sex activity closely identified with the hypothalamus and the visceral brain is enhanced by the neocortex.

Since morale is closely related to pattern maintenance and integration, the higher the morale and solidarity, the better the system can solve the problems of the system.

Since they commonly translate thoughts and feelings into deeds, hands naturally represent action, and since nearly half the characters in Great Expectations are of the underworld or closely allied to it, the linking of hands with crime or violence is not to be wondered at.

For circular fibers in a closely packed hexagonal array, the packing efficiency is given by: Af where Af, and 0.906 is the ratio of the area of a circle to that of the circumscribed hexagon.

The amateur is closely related to the collector, who is actually no more than the amateur who has taken to the field.

For while the past needs of the Church in this country may have been adequately met by collegiate institutions, which in temper and tone closely resembled junior colleges and finishing schools, it would seem that today's need is for the college which more closely resembles the university in its `` pursuit of excellence ''.

But in any case, one does not have to read very closely between the lines to realize that the situation is not regarded as a particularly happy one.

Colonialism alone would have been able to make these difficulties serious, for Christianity is so closely tied to colonialism in the minds of these people that repudiation of the one has tended automatically toward the repudiation of the other.

The order Caudata ( from the Latin cauda meaning " tail ") consists of the salamanders, elongated, low-slung animals that mostly resemble lizards in form, though this is a symplesiomorphic trait and the two groups are no more closely related than salamanders are to mammals.

Since the randomization-based analysis is complicated and is closely approximated by the approach using a normal linear model, most teachers emphasize the normal linear model approach.

To test the hypothesis that all treatments have exactly the same effect, the F-test's p-values closely approximate the permutation test's p-values: The approximation is particularly close when the design is balanced.

For the beatnik, like the hipster, is in opposition to a society that is based on the repression of the sex instinct.

The central concern of Erich Auerbach's impressive volume called Mimesis is to describe the shift from a classic theory of imitation ( based upon a recognition of levels of truth ) to a Christian theory of imitation in which the levels are dissolved.

The assumptions upon which the example shown in Figure 3 is based are: ( A ) One man can direct about six subordinates if the subordinates are chosen carefully so that they do not need too much personal coaching, indoctrinating, etc..

`` History has this in common with every other science: that the historian is not allowed to claim any single piece of knowledge, except where he can justify his claim by exhibiting to himself in the first place, and secondly to any one else who is both able and willing to follow his demonstration, the grounds upon which it is based.

Like ours, the economy of the space merchants must constantly expand in order to survive, and, like ours, it is based on the principle of `` ever increasing everybody's work and profits in the circle of consumption ''.

The American Medical Association is once again grinding out its tear-soaked propaganda based upon the high cost of the Veterans Administration medical program to the American taxpayer.

-- Your July 26 editorial regarding the position of Attorney General Robert F. Kennedy on prospective tax relief for DuPont stockholders is based on an erroneous statement of fact.

As is the case with the allotment provisions for support of vocational rehabilitation services, the matching requirements are also based on a statutory formula.

The shelter illustrated in figure 12 is based on such a room built in a new home in the Washington, D.C. area in the Spring of 1959.

The rules and policies to be applied in this process of course must be based on objectives which represent what is to be desired if radio service is to be of maximum use to the Nation.

This program is based on the policy of designing and building efficient machines which will help produce better textile values -- fabrics whose cost in relation to quality, fashion and utility provide the consumer with better textile products for the money.

But because science is based on mathematics doesn't mean that a hot rodder must necessarily be a mathematician.

and perhaps of even greater significance -- his music is strong 20th-Century evidence of the effectiveness of Evolution, based on a broad Traditionalism for the creative art of music.

Promotion is too often based on longevity and time in salary grade instead of merit.

The experimental arrangement as described below is based on the geometry of free burning arcs.

With detectors sensitive to three mass intervals and based on a few counts, the second and third Russian space probes indicate that the flux of the smallest particles detected is less than that of larger ones.

Oliver's 37-1/2 feet is partly based on this report and can be accepted as probable.

the former figure is based on a somewhat unusual birth of four by a Central American female ( see chapter on Laying, Brooding, Hatching, and Birth ), the latter on a `` normal '' newly born individual.

The following summary, based on Figures 5 and 6, is an example of one way of interpreting the 42 figures constructed from onset ages and completion ages of individual children with respect to the appropriate mean age for each growth center.

These differences in turn result from the fact that my Yokuts vocabularies were built up of terms selected mainly to insure unambiguity of English meaning between illiterate informants and myself, within a compact and uniform territorial area, but that Hoijer's vocabulary is based on Swadesh's second glottochronological list which aims at eliminating all items which might be culturally or geographically determined.