Once relatively inexpensive, Acthar Gel is currently an extremely expensive pharmaceutical product.

Once most of the system is built, the marginal cost of servicing additional clients or users tends to be relatively inexpensive, and may be negligible if there is no need to increase the peak capacity or the geographical extent of the network.

Once again the Italian moped scooter market was in a state of flux and would have to adapt and change as its smaller displacement units gave way to inexpensive imports.

Once the Bessemer process began to gain widespread use, other alloys of steel began to follow, such as mangalloy, an alloy of steel and manganese, which exhibits extreme hardness and toughness.

Once the Ionian revolt was finally crushed by the Persian victory at the Battle of Lade, Darius began plans to subjugate Greece.

Once judges began to regard each other's decisions to be binding precedent, the pre-Norman system of local customs and law varying in each locality was replaced by a system that was ( at least in theory, though not always in practice ) common throughout the whole country, hence the name " common law.

Once the price of inkjet printers dropped to the point where they were competitive with dot matrix printers, dot matrix printers began to fall out of favor for general use.

Once in office, when the Chinese began a buildup in the Kaesong sanctuary, he threatened to use nuclear force if an armistice were not concluded.

Once the new states began to form, conflicts among them began and dominance of the other nations could lead to wealth in the form of tribute.

Once the 1906 season got underway, many programs began experimenting with the forward pass.

Once protogalaxies began to form and contract, the first halo stars ( called Population III stars ) appeared within them.

Once land had been located that offered a better climate and room to expand, the group began plans to move.

Once equipped, he then began to learn turntablism and rapping.

Once war began in September 1939, Goebbels began a steady process of extending his influence over domestic policy.

Once the war began, there were frequent changes to the cabinet.

Once the talks began, Ribbentrop, who possessed a certain elan and sense of audacity, issued Sir John Simon an ultimatum.

Once memory theories like the Atkinson-Shiffrin memory model and Baddeley's working memory model were established as a theoretical framework in cognitive psychology, new cognitive frameworks of learning began to emerge during the 1970s, 80s, and 90s.

Once the financing was in place, Scorsese began to recruit his cast.

Once completed, a wave of assassinations of suspected Black September operatives began across Europe.

Once the modern World Series began in 1903, it took the Phillies 77 years from that point ( and 97 years from the club's establishment ) to win their first World Series — longer than any of the 16 teams that made up the major leagues for the first half of the 20th century.

Once the bombing and shelling had largely ceased, the ground invasion began as Soviet forces stormed the centre of Berlin street by street, building by building, aiming to capture the Reich Chancellery and other key symbols of the Nazi government.

Starting with the Once Upon a Time in Mexico DVD, Rodríguez began creating a series called, " Ten Minute Cooking School " where he revealed his recipe for " Puerco Pibil " ( based on Cochinita pibil, an old dish from Yucatán ), the same food Johnny Depp's character, " Agent Sands " ate in the film.

Once St Helena ’ s location was more widely known, English ships of war began to lie in wait in the area to attack Portuguese India carracks on their way home.

Once the SEALs assaulted MABOT via RHIB the Republican Guard forces immediately began to surrender.

Once in a while they said what a shame it was, with Granny dying, but they all agreed she wouldn't have wanted it any other way.

Once we have made clear that we are genuinely concerned with a country's development potential, we can be blunt in suggesting the technical conditions that must be met for development to occur.

Once the children have been commodified, Swift ’ s rhetoric can easily turn " people into animals, then meat, and from meat, logically, into tonnage worth a price per pound ".

Once he has received this blessing, the abbot not only becomes father of his monks in a spiritual sense, but their major superior under canon law, and has the additional authority to confer the ministries of acolyte and lector ( formerly, he could confer the minor orders, which are not sacraments, that these ministries have replaced ).

Once these projects have been approved by the United States Air Force or other agencies such as the CIA, and are ready to be announced to the public, operations of the aircraft are then moved to a normal air force base.

Once images have been acquired, the effects of decay and taphonomy must be accounted for before a correct anatomical reconstruction can be made.

Once the governing party-the National Movement Simeon II have not amassed enough votes to enter the parliament.

Once players have mastered these basic strokes, they can hit the shuttlecock from and to any part of the court, powerfully and softly as required.

CD-R is a Write Once Read Many ( WORM ) optical medium, although the whole disk does not have to be entirely written in the same session.

Once ten yards have been gained the offence gains a new set of three downs ( rather than the four downs given in American football ).

Once the team have come back empty handed, he argues with Scott for not telling him about the team he deployed to find former Acolytes.

Once all appeals have been exhausted on a case, the judgment is final and the action of the prosecution is closed ( code of penal procedure, art.

Once the High Lamas have found the home and the boy they believe to be the reincarnation, the boy undergoes a series of tests to affirm the rebirth.

Once these basic shapes have been assembled into a likeness, then the drawing can be refined into a more accurate and polished form.

Once the particles have accelerated to the required energies, separate electron and positron beams are brought into collision.

Once the onions have softened, niter kebbeh ( or, in the case of vegan dishes, vegetable oil ) is added.

Once trees have been removed by fire or logging, infiltration rates become high and erosion low to the degree the forest floor remains intact.

Once her sons had left for Paris, Eleanor may have encouraged the lords of the south to rise up and support them.

Once, Muhammad met a group of soldiers returning from a defensive battle and addressed them: " Welcome to the people who have concluded the minor jihad ( struggle ).

Once in the arena morgue, the corpse would have been stripped of armour, and probably had its throat cut to prove that dead was dead.

Once the actors are onboard the Protector, they finally realize the truth, but Sarris prevents them from leaving, so they assume their television roles in order to save the Thermians, who have very little concept of deception, or the art of acting / theater.

Nevertheless, Wells has this very same Time Traveller speak in terms unusual for socialist thought, referring as " perfect " and with no social problem unsolved, to an imagined world of stark class division between the rich assured of their wealth and comfort, and the rest of humanity assigned to lifelong toil: Once, life and property must have reached almost absolute safety.

Once the roots have reached the reservoir below, there is not a huge advantage with Bubbleponics over Deep Water Culture.

Once ignited and burnt, the combustion products — hot gases — have more available thermal energy than the original compressed fuel-air mixture ( which had higher chemical energy ).

Once he was done delivering the speech, everyone across the U. S. knew of the new AFL-CIO whose " mission to bring social and economic justice to our nation by enabling working people to have a voice on the job, in government, in a changing global economy and in their communities.