Once activated, p53 will induce a cell cycle arrest to allow either repair and survival of the cell or apoptosis to discard the damaged cell.

Once again, Titus personally compensated for the damaged regions.

Once over land, he circled twice to lose height, and cut his engine at an altitude of about, making a heavy landing due to the gusty wind conditions ; the undercarriage was damaged and one blade of the propeller was shattered, but Blériot was unhurt.

Once Tady and the others returned to the pits with their broken bikes, the former 500cc rider was permitted to go back out with a spare bike, as a mark of respect, but was ineligible to win since his original bike was badly damaged.

Once trained to perform a specific cognitive task these networks are often damaged or ' lesioned ' to simulate brain injury or impairment in an attempt to understand and compare the results to the effects of brain injury in humans.

Once perceived as a system exclusively involved in removing damaged protein from the cell, ubiquitination and subsequent protein degradation by the proteasome is now perceived as a universal regulatory mechanism for signal transduction whose importance approaches that of protein phosphorylation.

Once outer hair cells are damaged, they do not regenerate, and the result is a loss of sensitivity and an abnormally large growth of loudness ( known as recruitment ) in the part of the spectrum that the damaged cells serve.

Once completely damaged out, the tires will fall off and the car will be unusable for a few seconds before respawning.

Once the plane has landed, Bob is whisked away in a straitjacket, as everyone believes that he has gone insane ; however, the narrator informs the viewers that Bob's stay will be short-lived, and the final shot reveals why: The gremlin has left evidence of Bob's story, in the form of the damaged wing.

Once an ability is obtained, the only way Kirby can lose it is either by tapping a button in the bottom left corner or by being damaged.

Once clear of the tunnel, the canal passes Blisworth village and reaches Gayton Junction where the Northampton Arm branches off to the east.

Once a tunnel is found, the woodpecker chisels out wood until it makes an opening into the tunnel.

Once the team in possession of the ball has formed a successful phalanx, it attempts to pass the ball down the ' tunnel ' using the knees of the players forming it, to a player standing at the end of the phalanx, known as lines, whose job it is to kick the ball upfield.

Once a certain distance has been excavated ( roughly 1. 5-2 meters ), a new tunnel ring is built using the erector.

Once a tunnel is established, the network traffic between the peers is bidirectional.

Once per hour, the tunnel bores will be closed to regular traffic, and the trucks will be guided through the tunnel in a convoy with escorts.

Once construction was halted, the tunnel reached only to the height of the Jungfraujoch, rather than the Sphinx, with only two intermediate stations.

Once the decision was made to use the Cambie alignment for the Canada Line anyway, residents along the corridor successfully persuaded authorities to put the rail line in a tunnel instead of running it as a surface route, and to dig the tunnel using a tunnel boring machine.

Once the tunnel reaches a surge chamber at Louvie in Bagnes, it turns into a penstock which descends at a gradient of 73 % for until it reaches the power station.

Once the water main break was finally stopped on the same day, tunnel inspectors could enter the area.

Once the lots were full on weekends, traffic coming from the George Washington Bridge would be sent down the road towards the Lincoln Tunnel and the traffic coming from the tunnel would be sent towards the bridge, with no real place to go.

Once the SSH tunnel has been established, the user can connect to the specified local port to access the network service.

Once out of the tunnel, the L takes Ulloa Street to 15th Avenue and turns onto Taraval Street.

Once they had found a pay streak, miners would tunnel horizontally from the bottom of their prospect shaft, and follow the gold along the surface of the bedrock.

Once a ship has entered this tunnel, the forces inside propel it at incredible speed.

Pune -> Express way to Mumbai ( ask them for Khopoli exit, as you will pay lesser toll money ) -> Keep cruising along the expressway till the Ghats -> In the Ghats, locate the Khopoli exit ( it comes after the second tunnel ) -> Reach Khopoli and from there take the road to Pen ( may be marked as Alibaug as well ) -> Once in Pen, pass through the town to reach Mumbai-Goa highway -> Keep moving towards Alibaug -> around 1 – 2 km before Alibaug, take a left on the highway, to a road for Murud or Revdanda -> From there, keep following the road towards Murud at every intersection -> Around 35 – 37 km after Alibaug ( approx 20 km before Murud ) you will reach Kashid.

Once it was in use, the two tracks through the original tunnel were replaced by a single track along the centre ; the tunnel lining was repaired and thickened, and this tunnel then formed the up ( southbound ) single-line tunnel.

Once, pressing him, I learned that his job was only part-time, in the afternoons when nothing went on in the hall.

Once the door was open, they crowded him inside the dark building.

Once again, Tom Horn was the first and most likely suspect, and he was brought in for questioning immediately.

Once ( this was on the third day of school ) she kneeled down to pick up some books where they'd dropped on the floor and Jack looked up her dress -- at the bare expanse of incredibly white leg.

Once, then -- for how many years or how few does not matter -- my world was bound round by fences, when I was too small to reach the apple tree bough, to twist my knee over it and pull myself up.

Once covertly looking at Simms Purdew, the only man in the world whom he hated, he had seen the heavy, slack, bestubbled jaw open and close to emit the cruel, obscene banter, and had seen the pale-blue eyes go watery with whisky and merriment, and suddenly he was not seeing the face of that vile creature.

Once her trembling hand, with the pen grasped tight in it, was pressed against the paper the words came sharply, smoothly, as authoritatively as they would dropping from her own lips.

Once in a while they said what a shame it was, with Granny dying, but they all agreed she wouldn't have wanted it any other way.

Once the principle was established, the increase in state-owned vehicles came rapidly.

Once the full extent of this Russian military penetration of Cuba was clear, President Kennedy announced we would take whatever action was appropriate to prevent this, even if we had to go it alone.

Once the question of emancipation was settled to Palfrey's satisfaction, he faced a real problem in placing the freedmen in suitable homes as servants.

Once regarded as an agricultural nuisance, psyllium was sold in the 1930's as a mechanical laxative under 117 different brands.

`` Once, when the editor was just out of the hospital from a gallstone operation, Mrs. Calhoun and the mother of the bride went out to his house and fought it out beside his bed.

Once out in the street, the traffic was a gadfly maze in which he wandered stricken.

Once the figure was 30-30.

Once when she asked why he never went swimming and he answered, `` Don't feel like it '', he was tempted to tell her about being scared.

Once again, there was a negative shake.

Once it was, William thought.

They could still read the opening: `` Once, I was like you, stepping out of my window at the end of day, and letting the winds blow me gently toward the place I lived in.

Once his eyesight recovered sufficiently, he was able to study English literature at Balliol College, Oxford.

Once this was over, a massive development cooperation in the field of health and education brought in numerous civil personnel from Cuba.

Once he was firmly established in the Northern March, Albert's covetous eye lay also on the thinly populated lands to the north and east.