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Phase I and II reactions serve to increase the polarity and reduce the toxicity of the compounds, although many exceptions to the rule are seen.
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Phase and I
In many ways, Phase II can be considered an effort to make the earlier version ( never called Phase I ) more generic.
Phase I began in 1995, and limited sulfur dioxide emissions from 110 of the largest power plants to a combined total of 8. 7 million tons of sulfur dioxide.
One power plant in New England ( Merrimack ) was in Phase I.
from :-1700 till :-1500 text: Phase I
The first-in-human tests of a potential treatment are called Phase I studies.
The surfactant ( purple outline around particles ) positions itself on the interfaces between Phase II and Phase I, stabilizing the emulsion
Phase I of the GSM specifications were published in 1990.
In the Phase I trial enrolling five subjects with chronic HIV infection who had failed to respond to at least two antiretroviral regimens, a single intravenous infusion of autologous CD4 T cells genetically modified with VRX496 was safe and well tolerated.
Data from an ongoing Phase I / II clinical trial were presented at CROI 2009.
In the Phase I trial enrolling five subjects with chronic HIV infection who had failed to respond to at least two antiretroviral regimens, a single intravenous infusion of autologous CD4 T cells genetically modified with VRX496 was safe and well tolerated.
By 1987, the SDIO had developed a national missile defense concept called the Strategic Defense System Phase I Architecture.
Phase I was dedicated April 3, 2009.
I, " Superfluid and Vortex lines ; Disorder Fields, Phase Transitions ,", pp. 1 – 742, World Scientific ( Singapore, 1989 ); Paperback ISBN 9971-5-0210-0 ( readable online physik. fu-berlin. de )
In the US, studies are broken into Phase I, Phase II, and Phase III trials.
In December 2008, StemCells Inc., a biotech company in Palo Alto, received clearance from the U. S. Food and Drug Administration ( FDA ) to conduct Phase I clinical trials in PMD to assess the safety of transplanting human neural stem cells as a potential treatment for PMD.
* Phase I Environmental Site Assessment
As these target dates were missed, the Phase I process was later commenced on 1 November 2002, with Phase II and III beginning on 16 November 2003 and 21 February 2004 respectively.
Phase I ( 1974 )
( 1 ) Phase I companies: listed companies and financial institutions
Phase I companies:
Phase and II
A significant re-design was released in 1989 as AppleTalk Phase II.
Phase II also included changes to the underlying inter-networking protocols to make them less " chatty ", which had previously been a serious problem on networks that bridged over wide-area networks.
By this point Apple had a wide variety of communications products under development, and many of these were announced along with AppleTalk Phase II.
Phase II began in 2000, and affects most of the power plants in the country.
The most expensive was the building of the Phase II Silver Line tunnel under Fort Point Channel, done in coordination with Big Dig construction.
from :-1500 till :-1300 text: Phase II
Then, if these " digital modules " were able to build a self-sustaining business, the company would be free to use them to develop a complete computer in their Phase II.
With the company established and a successful product on the market, DEC turned its attention to the computer market once again as part of its planned " Phase II ".
Later studies, called Phase II and Phase III studies, enroll more people, and the goal is to determine whether the treatment actually works.
An emulsion of Phase II dispersed in Phase IC.
On September 8, 2006, the United States Senate Select Committee on Intelligence released " Phase II " of its report on prewar intelligence on Iraq.
In " Phase II " of their career, Dean Torrence led the touring operation.
* JNJ-Q2 Completed Phase II for MRSA
Many of these are set in the time of The Original Series, including Star Trek: Phase II which was nominated for a Hugo Award and received support from actors and writers who were involved with The Original Series.
This was the second time that Paramount had considered launching a network anchored by a Star Trek show: the studio planned to launch a network showcasing Star Trek: Phase II in 1977.
Category: Star Trek: Phase II characters
Ralph McQuarrie's redesigned Enterprise from Star Trek: Phase II
Before Star Trek: The Motion Picture, Paramount had planned a new Star Trek television series to have been named Star Trek: Phase II.
Phase and reactions
Phase I reactions ( also termed nonsynthetic reactions ) may occur by oxidation, reduction, hydrolysis, cyclization, and decyclization addition of oxygen or removal of hydrogen, carried out by mixed function oxidases, often in the liver.
Phase II reactions — usually known as conjugation reactions ( e. g., with
Products of conjugation reactions have increased molecular weight and tend to be less active than their substrates, unlike Phase I reactions which often produce active metabolites.
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