In town are the remnants of two castles from the Zemene Mesafint (" Era of Princes "), one ( pictured ) owned by Dej Desta, the other by the Ras Sebhat Aregawi.

Her father, Ras Betul Haile Maryam was less well known than her uncle Dejazmach Wube Haile Maryam, who was the ruler of much of Northern Ethiopia in the 1840s, and a rival of Emperor Tewodros II.

During the various wars between Ras Ali and his leading rival for power, Dejazmach Wube Haile Maryam of Semien, Emperor Yohannes was deposed and restored several times between 30 August 1840 and 1851, alternating with his cousin Sahle Dengel.

" Former diplomat Paul B. Henze supports this view that Aklilu was not interested in reform, but repeats Aklilu's rival Ras Asrate's opinion that " Aklilu was the primary reactionary influence on the Emperor.

Tekle Giyorgis then left for the court of Wolde Selassie's rival, Ras Gebre, and stirred up trouble between the two until Wolde Selassie met Gebre, and was undeceived ; Ras Wolde Selassie took custody of Tekle Giyorgis and afterwards exiled him to Axum, where he was kept under close watch until the Ras ' death.

When Hezqeyas heard that his rival had left Emakina, he advanced at the head of an army from Gondar, first to Tsenjana, then to the house of Dejazmach Haile Eshte where they were joined by Ras Aligaz, where they " took counsel together.

On his side, Dejazmach Haile Selassie resented that his cousin and rival Seyoum held the title of Ras while he was relegated to the lower rank of Dejazmach.

For much his reign Ras Ali was constantly at war, either putting down rebellions in his core territories, or defending his territory from rival warlords.

This family of proteins is homologous to Ras GTPases and is also called the Ras superfamily GTPases.

Ras is the name given to a family of related proteins found inside cells, including human cells.

All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells ( cellular signal transduction ).

The name ' Ras ' is an abbreviation of ' Rat sarcoma ', reflecting the way the first members of the protein family were discovered.

Other proteins exist which may augment the activity of Ras family proteins.

One example is GDI ( GDP Disassociation Inhibitor ); These function by slowing the exchange of GDP for GTP and thus, prolonging the inactive state of Ras family members.

Mutations in the Ras family of proto-oncogenes ( comprising H-Ras, N-Ras and K-Ras ) are very common, being found in 20 % to 30 % of all human tumours.

The Ras family is generally responsible for cell proliferation, Rho for cell morphology, Ran for nuclear transport and Rab and Arf for vesicle transport.

Her father's mother was a daughter of Ras Guga, a member of the powerful ruling family of Yejju, which was of Oromo origin and had converted to Christianity from Islam, and which had ruled as Regents for the powerless Emperors in Gondar during the Zemene Mesafint (" Era of the Princes ").

Of the three members ( H, N and K ) of the Ras family, K-Ras is the form found most often mutated in cancer.

Her mother Woizer Tishal was a member of a noble family of Begemder, while her paternal grandfather, Ras Wodajo, was a powerful and highly influential figure.

The Rab family of proteins is a member of the Ras superfamily of monomeric G proteins.

He was largely a figurehead, with real power in the hands of the Enderase or Regent, Ras Ali II a princeling of the Oromo ruling family of the district of Yejju.

Although a group of Tigrean nobles led by Ras Alula attempted to promote the claim of Ras Mengesha Yohannes ( the " natural " son of Yohannes ) as Emperor, many of the dead monarch's other relatives on both the Enderta and Tembien sides of his family objected and went into open rebellion against Mengesha.

A short time thereafter, he embraced a strict form of Christianity, adopted the name Ras Shorty I and moved with his family to the Piparo forest in the hills of southern Trinidad, where he and his family focused on creating faith-based music.

Hans Ras was born in 1926 in Rotterdam, the Netherlands, as the third son of a family of four children.

On expiry of Ras ’ three-year contract there, the family moved back to Leiden, where Ras became a lecturer in the Department of Languages and Cultures of Southeast Asia and Oceania.

Not long after this, the Ras family left the Netherlands for Jakarta to make the necessary preparations for the establishment of the first Indonesian office of the KITLV there.

In neurons, FLIM imaging using pulsed illumination has been used to study Ras, CaMKII, Rac, and Ran family proteins.

This homologous sequence is in the central portion of neurofibromin and being similar to the GAP family is recognized as a negative regulator of the Ras kinase.

* Al Qasimi family in Sharjah and Ras al-Khaimah

The forces were divided among Emperor Menelik, Empress Taytu Betul, Ras Welle Betul, Ras Mengesha Atikem, Ras Mengesha Yohannes, Ras Alula Engida, Ras Mikael of Wollo, Ras Makonnen Wolde Mikael, Fitawrari Gebeyyehu, and Negus Tekle Haymanot Tessemma.

The Emperor had risen early to begin prayers for divine guidance when spies from Ras Alula, his chief military advisor, brought him news that the Italians were advancing.

Negus Tekle Haymanot commanded the right wing, Ras Alula the left, and Rasses Makonnen and Mengesha the center, with Ras Mikael at the head of the Oromo cavalry ; the Emperor and his consort remained with the reserve.

* 1842 – Battle of Debre Tabor: Ras Ali Alula, Regent of the Emperor of Ethiopia defeats warlord Wube Haile Maryam of Semien.

The Italians expected disaffected potentates like Negus Tekle Haymanot of Gojjam, Ras Mengesha Yohannes, and the Sultan of Aussa to join them ; instead, all of the ethnic Tigrayan or Amharic peoples flocked to the Emperor Menelik's side in a display of both nationalism and anti-Italian feeling, while other peoples of dubious loyalty ( e. g. the Sultan of Aussa ), were watched by Imperial garrisons.

" The two most important historical figures who signify the introduction of the concepts of national boundary and sovereignty in Ethiopia are Emperor Menelik II and Ras Gobana Dachi, who used guns manufactured in Europe to bring a large swath of Biyas ( regions / nations ) under a centralized rule.

By the 1880s, Sahle Selassie, king of Shewa ( the later Emperor Menelik II ) allied with Ras Gobena's Shewan Oromo militia to expand his kingdom to the South and East, expanding into areas that hadn't been held together since the invasion of Ahmed Gragn.

* February 7 – Battle of Debre Tabor: Ras Ali Alula, Regent of the Emperor of Ethiopia, defeats warlord Wube Haile Maryam of Semien.

* October 6 – The Roman Catholic Ras Sela Kristos, half-brother of the Emperor Susenyos crushes a group of rebels in at Mount Amedamit in Gojjam, who were opposed to Susenyos ' pro-Catholic beliefs.

* May 23 – Ras Gugsa of Yejju, Regent of the Emperor of Ethiopia

* May – The Three battles of Sarbakusa: an alliance of three of the most powerful aristocrats of Ethiopia – Goshu of Amhara, Wand Bewossen, and Fasil of Damot – defeats Ras Mikael Sehul and Emperor Tekle Haymanot I, taking control of Ethiopia.

The Serbs and Bulgars concluded peace, and the Christianization of the Slavs began ; by the 870s the Serbs were baptized and had established the Eparchy of Ras, on the order of Emperor Basil I.

The Serbs and Bulgars concluded peace, and the Christianization of the Slavs began ; by the 870s the Serbs were baptized and had established the Eparchy of Ras, on the order of Emperor Basil I.

On the one hand, Napier made it clear to the Ethiopians that the sole intent of the British force was to rescue the imprisoned Europeans — not conquest ; on the other, Napier met with local potentates such as Ras Kassa ( the future Emperor Yohannes IV ), and arranged to purchase needed supplies with the 4. 35 million Maria Theresa Thalers ( the preferred currency of the area ) the British had purchased from the mint in Vienna.

In May 1909, shortly before the Emperor made this decision, Lij Iyasu was married to Woizero Romanework Mengesha, the daughter of Ras Mengesha Yohannes, granddaughter of Emperor Yohannes IV, and the niece of Empress Taitu.

Having deeply alienated Ras Kassa with his escape, and having deeply angered the Emperor, Iyasu was taken to a fortress on the slopes of Mount Gara Muleta in Girawa, where he was guarded closely by locals loyal to Emperor Haile Selassie.

Following a chance meeting with Ras Taferi Makonnen ( the later Emperor Haile Selassie ), he received a scholarship to study in France, and spent eight years at the University of Montpellier, where he received his doctorate in Law.