* Significant clinical discomfort or impairment at work, social situations, or other important life areas.

Significant emphasis was also placed on town planning, with new conservation areas introduced and a new generation of new towns built, notably Milton Keynes – this trend itself a continuation of efforts initiated in the latter years of the preceding Conservative administration.

Significant areas have been converted to plantations, or for use in agriculture and pasture.

Significant remaining forested areas are in the Gascony region and north in the Alsace-Ardennes area.

Significant additions have been made to the campus since January 1999, when a powerful tornado destroyed nearly complete new school buildings and historic residential areas surrounding the downtown area.

Significant amounts of precipitation occur in all seasons in most areas.

Significant concentrations of support exist in the north of the city, areas such as Hillsborough, Stannington, Parson Cross, Ecclesfield, Chapeltown, Wisewood, and Stocksbridge in particular.

Significant numbers of Russians and other Slavs, as well as groups from various nationalities mainly from the Caucasus, migrated to urban areas.

Significant areas of farmland were abandoned during the Great Depression and incorporated into nascent national forests.

Significant water areas include the Shawsheen River and Haggetts Pond, located in west Andover, which serves as the town's reservoir.

Significant non-surge areas of Escambia County south of US 98 were included in evacuation areas because of the potential for isolation by flooding.

Significant portions of the river's shores are within the Mystic River Reservation and are administered by the Massachusetts Department of Conservation and Recreation, which include a variety of recreation areas.

Significant areas of the park are pine plantations ( white and red ) from the mid-twentieth century, when the land was purchased, originally as the Athens State Forest.

* Significant expansion of current Institute of Peace program involvement in educational affairs, in areas such as:

Significant severe areas ( referred to as " hatched areas " because of their representation on outlook maps ) refer to a threat of increased storm intensity that is of " significant severe " ( F2 / EF2 or stronger tornado, 2 inches ( 5 cm ) or larger hail, or 75 mph ( 120 km / h ) winds or greater ) level.

Significant areas of the collection include antiquities, specifically their collection of Egyptian antiquities spanning over 3, 000 years.

Significant wetland areas in Mount Waverley are found within Valley Reserve and in the Scotchmans Creek valley.

Significant rainfall was also recorded in the Carolinas and Georgia, with numerous areas recording over.

Significant problems occur with airports where the grounds were or have become nesting areas for birds.

Significant areas have become desertified following extensive slash-and-burn activity primarily from 1970 onward, as population pressures led indigenous peoples to seek agricultural production in increasingly unsustainable methods.

Significant areas of thought on identity fermented over the long centuries of seclusion under the Tokugawa regime.

Significant flooding was a serious problem for the local population and a major flood in 1877 led to widespread erosion and changed the course of the river in several areas.

Significant factors in the development of armour include the economic and technological necessities of armour production.

Significant industries include IT, pharmaceuticals, biomedical engineering, biotechnology, electronics, traffic engineering, and renewable energy.

: Significant rivers include the Jimani River, Río Yaque del Norte, Río Jamao del Norte, Río Isabela and the Ozama River

Significant strands of this infrastructure include: The Scottish Arts Council, Edinburgh College of Art, Talbot Rice Gallery ( University of Edinburgh ) and the Edinburgh Annuale.

* African festivals Significant African festivals based on the continent include the biannual Panafrican Film and Television Festival of Ouagadougou FESPACO in Burkina Faso, the annual Durban International Film Festival which has grown in importance for industry with the addition of a co-production forum and Talent Campus.

Significant parallels include the prince feigning madness, his mother's hasty marriage to the usurper, the prince killing a hidden spy, and the prince substituting the execution of two retainers for his own.

Significant publications include a collection of texts, a grammar and a lexicon ( both published posthumously ), in addition to a theoretically significant article on Menomini phonological alternations.

Significant fields of study in microeconomics include general equilibrium, markets under asymmetric information, choice under uncertainty and economic applications of game theory.

Significant finds include the Superior Valley 014 Acapulcoite, one of two of its type found within the United States as well as the Blue Eagle meteorite, the first Rumuruti-type chondrite yet found in the Americas.

Significant AOR offshoots include classic rock and adult album alternative.

Significant investigations conducted by the NTSB in all modes of transportation in recent years include the collapse of the I-35 highway bridge in Minneapolis, Minnesota ; the collision between two transit trains in Washington, D. C .; the pipeline explosion that destroyed much of a neighborhood in San Bruno, California ; the sinking of an amphibious vessel in Philadelphia, Pennsylvania ; and the crash of a regional airliner near Buffalo, New York.

Significant natural resources in Ukraine include: iron ore, coal, manganese, natural gas, oil, salt, sulfur, graphite, titanium, magnesium, kaolin, nickel, mercury, timber, and arable land.

Significant passages include the beloved Laus Italiae of Book 2, the prologue description of the temple in Book 3, and the description of the plague at the end of Book 3.

Significant fashion trends of the 1960s include:

Significant hairstyle trends of the 1980s include the Perm ( started popularity in the late 1970s ), the Mullet ( evolved from the 1970s to a cleaner look using hair gel ), the Jheri curl, the Flattop, the Hi-top fade and Big hair.

Significant clothing trends of the 1980s include Shoulder pads, Jean jackets, Leather pants, Aviator jackets, Jumpsuits, Diane von Fürstenberg Wrap Dress, Members Only Jackets, Skin-tight acid-washed jeans, Miniskirts, Leggings and Leg warmers ( popularized in the film " Flashdance "), Off-the-Shoulder Shirts and Cut Sweatshirts ( popularized in the film " Flashdance ").

Significant windstorms in Clark County include the Columbus Day windstorm of October 12, 1962, and an April 6, 1972 tornado which rated F3 on the Fujita scale, striking a local school.

Significant through roads in Kensington include Maryland Routes 185 ( Connecticut Avenue ), 193 ( University Boulevard West ), and 547 ( Knowles Avenue ).

Significant crops in montane forest zones include tea and coffee, and the logging of unique species causes changes to the forest structure.

Significant blizzards include:

Significant factors in the local economy include services such as banking, insurance, healthcare and logistics.

Significant weather forecasting problems that occur in the 0-to 12-hr range include severe weather in all seasons ( for example, tornadoes, thunderstorms, snow, and ice storms ) and hazards to aviation ( for example, clear air turbulence, icing, and downbursts ).

Significant film appearances include The Snow Creature ( 1954 ), Half Human ( 1955 ), The Abominable Snowman ( 1957 ), Yeti-il gigante del 20. secolo ( 1977 ), Snowbeast ( 1977 ), Monsters, Inc. ( 2001 ), and The Mummy: Tomb of the Dragon Emperor ( 2008 ), Yeti: Curse of the Snow Demon, ( 2008 ) Yetiko Khojima ( Yeti ; in search of Yeti, 2010 ).

Significant towns in the county include Brilliant, Guin, Hackleburg, Hamilton and Winfield.