Since the regulation of vascularization in the mature retina involves a balance between endogenous positive growth factors, such as vascular endothelial growth factor ( VEGF ) and inhibitors of angiogenesis, such as pigment epithelium-derived factor ( PEDF ), rAAV-mediated expression of PEDF, angiostatin, and the soluble VEGF receptor sFlt-1, which are all antiangiogenic proteins, have been shown to reduce aberrant vessel formation in animal models.

* Familiar size – Since the visual angle of an object projected onto the retina decreases with distance, this information can be combined with previous knowledge of the object's size to determine the absolute depth of the object.

Ophthalmologist Walter B. Lancaster had this to say: " Since seeing is only partly a matter of the image on the retina and the sensation it produces, but is in still larger part a matter of the cerebral processes of synthesis, in which memories play a principal role, it follows that by repetition, by practice, by exercises, one builds up a substratum of memories useful for the interpretation of sensations and facilitates the syntheses which are the major part of seeing.

Since there are few porphyrins naturally found in the skin, the treatment is believed safe except in patients with porphyria ; although eye protection is used due to light-sensitive chemicals in the retina.

Since the absorbance of light by retina pigments corresponds to the wavelengths that best activate photoreceptor cells, this experiment showed the wavelengths that the eye could best detect.

Since the vision processing pathways are still intact, a person who has lost the ability to retrieve data from the retina can still see subjective images by using data gathered from other sensory modalities such as touch or audition.

Since these cells respond mostly to blue light, it has been suggested that they have a role in mesopic vision and that the old theory of a purely duplex retina with rod ( dark ) and cone ( light ) light vision was simplistic.

Since the work is done by hand, the only limitation, it is said, `` is that of human conception ''.

Since many scientific applications require incubation at temperatures close to human body temperature ( 37 ° C ), agar is more appropriate than other solidifying agents that melt at this temperature, such as gelatin.

Since human plague is rare in most parts of the world, there is no need to vaccinate people other than those at particularly high risk of exposure.

Since meat has a higher energy density than vegetables, and cooking it allows more nutrients to be liberated to the body, the introduction of cooked meat in the human diet reduced the energy requirements of the digestive system.

Since people are human, one should teach first about humans, not machines or techniques.

Since Galen states that he is using observations of monkeys ( human dissection was prohibited ) to give an account of what the body looks like, Vesalius could portray himself as using Galen's approach of description of direct observation to create a record of the exact details of the human body, since he worked in a time when human dissection was allowed.

Since the early 1940s, Kingman Reef has had very little human contact, though amateur radio operators from around the world have occasionally visited the reef to put it " on the air " in what is known as a DX-pedition.

Since this fountain ends in death, it may also simply represent the life span of a human, from violent birth to a sinking end.

:" Since you desire to know everything, I have written this ' book of notes ,' that you may learn of what the universe and its elements consist, what the world contains, and what the human race has done.

Since the expulsion the UK has suspended direct government aid, citing concerns over governance and human rights.

Since the CFCs themselves are equally powerful greenhouse gases, the mere substitution of HFCs for CFCs does not significantly increase the rate of anthropogenic global warming, but over time a steady increase in their use could increase the danger that human activity will change the climate.

Since organizations can be viewed as systems, management can also be defined as human action, including design, to facilitate the production of useful outcomes from a system.

Since it must have been deliberately placed there, this could indicate one of the first ( known ) human finds of a meteorite in Europe.

Since 2004, she has also been Professor of Practice in International Affairs at Columbia University, where she teaches international human rights.

Since all people including the most isolated indigenous groups such as the Andamanese or the Tasmanian aboriginals possess language, then it was presumedly present in the ancestral populations in Africa before the human population split into various groups to inhabit the rest of the world.

Since reason is the means of human knowledge, it is therefore each person's most fundamental means of survival and is necessary to the achievement of values.

Since the 1970s, dozens of oncogenes have been identified in human cancer.

If one adds two whole parts the result is one whole and if one whole is subtracted from another whole the result is another whole-it means there is one whole universe and it is all prevaded by " Him ". Since the universe has come forth from the Divine, all things and beings are sacred and must be treated so in human thought and action.

" Since the human race started from the point of greatest poverty, that is, from the point where there were the most obstacles to be overcome, it is clear that all that has been gained from one era to the next has been due to the spirit of property.

Since the soul is a spiritual substance it is not brought into being through transformation of matter, but directly by God, whence the special uniqueness of each person .." Fifty years later, Pope John Paul II, stating that scientific evidence now seemed to favour the evolutionary theory, upheld the distinction of Pius XII regarding the human soul.

Since people are human, one should teach first about humans, not machines or techniques.

Since the breakup of the former Yugoslavia, Slovenia has instituted a stable, multi-party, democratic political system, characterized by regular elections, a free press, and an excellent human rights record.

Since the ongoing civil war of 2011, and associated killings and human rights abuses, Syria has been increasingly isolated from the countries in the region, and the wider international community.

Since the overwhelming majority of light rays from a given light source do not make it directly into the viewer's eye, a " forward " simulation could potentially waste a tremendous amount of computation on light paths that are never recorded.

Since looking directly at the Sun with the naked eye permanently damages vision, amateur observation of sunspots is generally conducted indirectly using projected images, or directly through protective filters.

Since olive trees are not very tall, this would suggest that the condemned was crucified at eye level.

Since the cones have a much lesser power of merging signals, the fovea allows for the sharpest vision the eye can attain.

Since 2002, a topical emulsion of ciclosporin for treating inflammation caused by keratoconjunctivitis sicca ( dry eye syndrome ) has been marketed under the trade name Restasis ( 0. 05 %).

Since objects can be seen by light in the visible spectrum from a source reflecting off their surfaces and hitting the viewer's eye, the most natural form of invisibility ( whether real or fictional ) is an object that neither reflects nor absorbs light ( that is, it allows light to pass through it ).

Since there is no form of punishment in the Torah that calls for the maiming of an offender, there is no case where a conspiratorial false witness could possibly be punished by the court injuring to his eye, tooth, hand, or foot.

Since the oculomotor nerve controls most of the eye muscles, it may be easier to detect damage to it.

Since the raster image is only perceptible to the human eye as a whole for a very short time, the raster must be refreshed many times per second to give the appearance of a persistent display.

Since her retirement in 1999, she has stayed away from the public eye and rarely gives interviews to talk about her past with Sierra On-Line.

* Since ( by definition ), binocular depth perception requires two functioning eyes, a person with only one functioning eye has no binocular depth perception.

Since the camera is only able to see the electromagnetic radiation that is impossible to detect with the human eye, it will build a picture in the viewer and record a visible picture, usually in a JPG format.

Since most analytes are not visible to the naked eye a detector is needed.

Since an image from the compound eye is created from the independent picture elements produced by ommatidia, it is important for the ommatidia to react only to that part of the scene directly in front of it.

* Since the depth-fail method only offers an advantage over depth-pass in the special case where the eye is within a shadow volume, it is preferable to check for this case, and use depth-pass wherever possible.

Since first contact leaves an impression on the buyer, professional conduct, including attire, a handshake, and eye contact, is advised.

Since the eye is an optical system, radiance and its cousin luminance are good indicators of how bright an object will appear.

Since then the number of such groups has consolidated to around 50, of which 14 are still regularly in the eye of police.

Since a building that contains Prussian blue staining would exhibit much higher levels of detectable cyanides than one without anyway, Green writes that Leuchter's and Rudolf's measurements reveal nothing more than what is already visible to the naked eye.

" Since the early 1990s, Los Angeles – based artist Uta Barth has examined photographic and visual perception — how the human eye sees differently from the camera lens and how the incidental and atmospheric can become subject matter in and of themselves.

Since then, the Dawgz have won 3 straight to push their record to 7-5 with an eye still on the playoffs.

Since vultures frequently can be seen flying in numbers ( groups are called " kettles "), Zone-tailed Hawks can mingle with them and are perhaps most often missed by the human eye in such kettles.