Such disorders usually manifest in early childhood and affect predominantly tissues with high energy demands ( brain, heart, muscle ).

Such conflicting demands may exacerbate ethnic and national conflicts and make their resolution more difficult.

Such narcissists maintain self-esteem by seeing themselves as misunderstood and a subject to intolerable demands.

Such " council schools ", also referred to in Mississippi lexicon as " academies ", were established by the White Citizens ' Council movement in reaction to the demands for racial integration by the American Civil Rights movement.

Such was not to be, but he showed his tough streak within the cabinet when he forced McMahon to accede to the Country Party's demands on petrol prices and other issues which affected rural voters.

Such demands intend to challenge the capitalist class's right to rule.

Such security concerns led to demands for a year-round transportation system that British reinforcements could use should their territory be attacked during winter when the St. Lawrence River was frozen, and the only railway for British reinforcements to use would be the Grand Trunk connection at Portland, in the United States.

Such demands on energy, if long continued, would produce a strong, virile, and self-contained race which would inevitably overwhelm in battle nations whose weaker elements had not been purged by the conditions of an equally severe environment.

Such demands were unfeasible for Qasim who knew that such a concession would damage his image, and the military campaign waged on against Barzani's rebellion.

Such complexity demands a more rigorous mode of research that is capable of dealing with the complications of socio-educational experience.

Such " confederations " acted in lieu of state authority or to force their demands upon that authority.

Such a firebox could sustain a rate of steam generation to meet any demands of the locomotive's cylinders, even at high speed.

Such an understanding of limited government, as explained by James Madison, does not place arbitrary and ideologically biased parameters on the actions of a government thus allowing government to change as time demands.

Such demands constrained female birth intervals and consequently their fertility ; thus providing an opportunity for selection to favour the grandmother hypothesis.

Such concerns have continued to underpin Tillyer's practice to the present day, the artist balancing formal and technical experimentation against the demands of subject matter-demanding multiple reactions from the viewer.

Such tuning is through to better facilitate the technical demands imposed on the lead guitarist in the creation of new motifs and variations.

Such stretches have an inhuman moonlike quality.

Such writers as William Faulkner and Robert Penn Warren have led the field of somewhat less important writers in a sort of post-bellum renaissance.

Such problems are of extreme interest as well as importance and are so much like fighting in a rain forest or guerrilla warfare at night in tall grass that we might have to re-examine primitive conflicts for what they could teach.

Such activity may or may not have irritated the Kremlin, but it has frequently condemned America to an unnatural defensiveness that has undermined our effort to give leadership to the free world.

Such performance is a great tribute to American scientists and engineers, who in the past five years have had to telescope time and technology to develop these long-range ballistic missiles, where America had none before.

Such a situation regarding the Board of War could hardly have helped Morgan's chances for promotion when that matter came before the group later on.

Such treatments of the conjugates have usually been successful in eliminating nonspecific staining in several other systems ( Coons, 1958 ).

Such a difference might have resulted from: 1.

Such associations suit well with the gothic or mystery-story aspects of Dickens' novel, but, on a deeper plane, they relate to the themes of sin, guilt, and pursuit that have recently been analyzed by other critics.

`` Such a vicious statement can only have its origin in the desire of a new political candidate to try to make his name known by condemning a man of world stature.

Such a decision should have placed a powerful weapon in the hands of the entire housing industry, but there is little evidence that realtors, or at least their associations, have repudiated the principle in such clauses.

Such a man must be able and willing to give clear and sensible advice to the whole group, a person in whom all the member nations will have absolute confidence.

Such cooperative behaviors have sometimes been seen as arguments for left-wing politics such by the Russian zoologist and anarchist Peter Kropotkin in his 1902 book Mutual Aid: A Factor of Evolution and Peter Singer in his book A Darwinian Left.

Such defenders, or rather destroyers, of the church, have caused themselves to be called abbots, and presumed to attribute to themselves a title, as well as estates, to which they have no just claim.

Such a deep controversy within the Church during this period of its development could not have materialized without significant historical influences providing a basis for the Arian doctrines.

Such ideas are described as " Counter-Enlightenment " because they are contrary to the Enlightenment's ideal that humans have the capacity to make their lives and societies a heaven on earth using their own power and reason.

Such names have not yet been shown conclusively to predate the twelfth century, but there are indications that they may be considerably older.

Such changes could have rendered previous methods of codebreaking insufficient, with serious implications for the conduct of the war.

Such influence has caused Aramaic to have many Persian loanwords that can be seen in later historical texts.

Such numbers may have amounted to a substantial proportion, if not all, of the Peucini Bastarnae: Victor claims that the Carpi resettled in Pannonia by Diocletian at the same time, together with those previously transferred by Aurelian, amounted to the entire Carpi tribe.

Such restrictions have been said to account for the animal's limited distribution.

Such agents have duties to discharge of a fiduciary nature towards their principal.

Such printers would have either 9 or 24 pins on the print head.

Such doors pose a substantial fire risk to occupants of occupied buildings when they are locked.

Such projects have the additional effect of constricting downstream water supply ; Toktogul deprives the lower reaches of the Syr Darya in Uzbekistan and the Aral Sea Basin of substantial amounts of water.

Such anomalies would include any sudden and substantial increase in funds, a large withdrawal, or moving money to a bank secrecy jurisdiction.

Such languages demonstrate a preference for singular pronouns but attest plurals in a substantial minority of cases.

Such interactions have become both more numerous and more continual and substantial in recent times.

Such elements include the essential idea of narrative structure, with identifiable beginnings, middles and endings, or exposition-development-climax-resolution-denouement, normally constructed into coherent plot lines ; a strong focus on temporality, which includes retention of the past, attention to present action, and protention / future anticipation ; a substantial focus on characters and characterization which is " arguably the most important single component of the novel "; a given heterogloss of different voices dialogically at play – " the sound of the human voice, or many voices, speaking in a variety of accents, rhythms and registers "; possesses a narrator or narrator-like voice, which by definition " addresses " and " interacts with " reading audiences ( see Reader Response theory ); communicates with a Wayne Booth-esque rhetorical thrust, a dialectic process of interpretation, which is at times beneath the surface, conditioning a plotted narrative, and other at other times much more visible, " arguing " for and against various positions ; relies substantially on now-standard aesthetic figuration, particularly including the use of metaphor, metonymy, synecdoche and irony ( see Hayden White, Metahistory for expansion of this idea ); is often enmeshed in intertextuality, with copious connections, references, allusions, similarities, parallels, etc.

Such comparisons reveal that the treatment effect of TMS appears at least as effective as a variety of antidepressant medication therapies, but with a substantial reduction in the adverse effect burden that complicates the use of antidepressant medications.

Such clinal variation always indicates substantial gene flow among the apparently separate groups that make up the population ( s ).

Such stars are hypergiants and LBVs undergoing substantial mass loss due to Eddington instability, for example SN2005gl.

Such elements include the essential idea of narrative structure, with identifiable beginnings, middles and ends, or exposition-development-climax-denouement, with important inciting incidents, normally constructed into coherent plot lines ; a strong focus on temporality that includes retention of the past, attention to present action and protention / future anticipation ; a substantial focus on characters and characterization which is " arguably the most important single component of the novel " ( David Lodge The Art of Fiction 67 ); a given hetergloss of different voices dialogically at play, " the sound of the human voice, or many voices, speaking in a variety of accents, rhythms and registers " ( Lodge The Art of Fiction 97 ; see also the theory of Mikhail Bakhtin for expansion of this idea ); possesses a narrator or narrator-like voice, which by definition " addresses " and " interacts with " reading audiences ( see Reader Response theory ); communicates with a Wayne Booth-esque rhetorical thrust, a dialectic process of interpretation, which is at times beneath the surface, conditioning a plotted narrative, and other at other times much more visible, " arguing " for and against various positions ; relies substantially on now-standard aesthetic figuration, particularly including the use of metaphor, metonymy, synecdoche and irony ( see Hayden White, Metahistory for expansion of this idea ); is often enmeshed in intertextuality, with copious connections, references, allusions, similarities, parallels, etc.

Such positions were formally documented for the first time in 1697 by William Molyneux in a widely publicized letter to John Locke, and more extensively in 1713, when Anthony Collins wrote his Discourse of Free-thinking, which gained substantial popularity.

Such people are savvy businessmen that usually amass substantial fortunes in the process of running their business.

Such stationary engines were imprecise machines which often produced substantial exhaust smoke when fueled with kerosene, a common fuel used before catalytic cracking of petroleum became more common in the 1930s.

Such systems for consumers were first sold to cyclists, but by the 1990s also had found a substantial market among hikers.

Such complexity requires a substantial " energy " subsidy ( meaning resources, or other forms of wealth ).

Such complexity requires a substantial " energy " subsidy ( meaning the consumption of resources, or other forms of wealth ).

Such unions between Europeans, English, French and Portuguese, and local women, both Hindu and Muslim, were common throughout the 18th century in Calcutta, and are the origin of the city's substantial Anglo-Indian ( or Eurasian ) community today: by the early 19th century, however, increasing racial intolerance made marriages of this kind much rarer.

Such thresholds are to be published for public review and supported by substantial evidence before their adoption.

Such prizes are sometimes a substantial amount of money ; a social gaming hackathon at the TechCrunch Disrupt conference offered $ 250, 000 in funding to the winners.

Such a bag, if constructed of good Brussels carpeting and unquestionable workmanship, will last a lifetime, provided always that a substantial frame is used.

Such fines traditionally were paid with cattle or goats but nowadays substantial amounts of money can be asked for.

Such examples are hills, valley sides, mountains ( with substantial vegetation ) and buildings constructed from stone, brick or concrete but without reinforced steel.

Such a large improvement means that any substantial degree of anemia will have a large impact on the oxygen carrying capacity of the blood.