Such modifications can also determine the localization of the protein, e. g., the addition of long hydrophobic groups can cause a protein to bind to a phospholipid membrane.

Such " multi-subunit " assemblies usually involve a circular arrangement of identical or homologous proteins closely packed around a water-filled pore through the plane of the membrane or lipid bilayer.

Such studies estimate that at the MAM, which may comprise up to 20 % of the mitochondrial outer membrane, the ER and mitochondria are separated by a mere 10-25 nm and held together by protein tethering complexes.

Such movement can be described by the Fluid Mosaic Model, that describes the membrane as a mosaic of lipid molecules that act as a solvent for all the substances and proteins within it, so proteins and lipid molecules are then free to diffuse laterally through the lipid matrix and migrate over the membrane.

Such v-SNARES are hypothesised to exist on the vesicle membrane, while the complementary ones on the target membrane are known as t-SNAREs.

Such hypothetical civilizations have either transcended their universe of origin or arose within a multiverse or other higher-order membrane of existence, and are capable of universe-scale manipulation of individual discrete universes from an external frame of reference.

Such supplies include resistors and capacitors for RC-circuit frequency equalization, if necessary ; step-up transformers ; perforated metal sheets or grids and insulating plastics for the stators ; polymer film and conductive paint ( e. g. a liquid graphite suspension ) for the membrane ; simple tensioning equipment for proper membrane tuning ; and a frame, usually of wood, to hold everything together.

Such ion pumps take in ions from one side of the membrane ( decreasing its concentration there ) and release them on the other side ( increasing its concentration there ).

Such radicals and reactive oxygen species attack cell membrane lipids, proteins, and glycosaminoglycans, causing further damage.

Such a movement of one ion across the membrane would result in a net imbalance of charge across the membrane and a membrane potential.

Such water is produced using ion-exchange processes or combinations of membrane and ion-exchange methods.

Such signals can arise either from the release of stored calcium or the calcium influx across the plasma membrane, but more characteristically, from both routes.

Such an association with the plasma membrane creates the relatively new perception of the ER and theme of “ a neuron within a neuron .” The ER ’ s structural characteristics, ability to act as a Ca2 + sink, and specific Ca2 + releasing proteins, serve to create a system that may produce regenerative waves of Ca2 + release that may communicate both locally and globally in the cell.

Such unprecedented levels of computational power are key to investigating areas, such as designing fusion reactors that could provide carbon neutral, sustainable energy ; engineering proteins to provide new therapies for diseases or release energy from biomass efficiently ; studying climate change ; and designing new materials with specialized properties.

Such VCD studies of proteins are often combined with X-ray diffraction of protein crystals, FT-IR data for protein solutions in heavy water ( D < sub > 2 </ sub > O ), or ab initio quantum computations to provide unambiguous structural assignments that are unobtainable from CD.

Such work shows that the fetal proteins detected in pregnant woman ’ s blood originate from a diverse group of tissues and organs from the developing fetus.

Such proteins are capable of both homotropic and heterotropic interactions.

Such proteins can be separated from the biological membranes only using detergents, nonpolar solvents, or sometimes denaturing agents.

Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.

Such proteins violate Anfinsen's dogma.

Such proteins are involved in immune response, for example.

Such mechanism is necessary for incorporation of polar α-helices into structures of transmembrane proteins.

Such proteins include splicing activators that promote the usage of a particular splice site, and splicing repressors that reduce the usage of a particular site.

Such proteins contain RNA recognition motifs and arginine and serine-rich ( RS ) domains.

Such communication between proteins allows for the efficient transfer substrates from one active site to the next.

Such proteins are homologous to their functional analogues in organisms which thrive at lower temperatures, but have evolved to exhibit optimal function at much greater temperatures.

Such hyperthermostable proteins are often commercially important, as chemical reactions proceed faster at high temperatures.

Such antibodies are typically formed in response to an infection ( against a given microorganism ), against other foreign proteins ( in response, for example, to a mismatched blood transfusion ), or to one's own proteins ( in instances of autoimmune disease ).

Such receptors are closely related to chaperones ( namely heat shock proteins hsp90 and hsp56 ), which are required to maintain their inactive ( but receptive ) cytoplasmic conformation.

Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.

Such problems are of extreme interest as well as importance and are so much like fighting in a rain forest or guerrilla warfare at night in tall grass that we might have to re-examine primitive conflicts for what they could teach.

Such manipulations are frequently encountered in his essay on the suppression of the monasteries during the English reformation.

Such support should not be difficult to come by if all the plans to be presented by the NCTA are as attractive as this outline of express buses coming into the downtown area.

Such measures are essential to its job of presenting business and Government with the facts required to meet the objective of expanding business and improving the operation of the economy.

Such additional daytime class 2, assignments are appropriate if optimum use is to be made of these frequencies, and the Commission has over the years made a large number of them.

Such locks are nearly always used where the switch points `` face '' oncoming traffic.

Such disks are very handy for cutting and shaping small parts.

Such modifications are all for the best but it takes something as different as a Deerstalker or a Jet to change arms-making concepts.

Such sweeping distractions are hardly conducive to `` Oscar '' winning performances.

Such ambiguous exercises compound confusion by making it worse compounded, and they are sometimes expanded until the cream of the jest sours.

Such high-resolution observations as these are needed at several wave lengths in order that the radio emission of the moon can be properly interpreted.

Such an instrument is expected to be especially useful if it could be used to measure the elasticity of heavy pastes such as printing inks, paints, adhesives, molten plastics, and bread dough, for the elasticity is related to those various properties termed `` length '', `` shortness '', `` spinnability '', etc., which are usually judged by subjective methods at present.

Such an indicator, or indicators, are needed as means of recognizing specific periods of delay in skeletal developmental progress.

Such specialized training institutions could be located near the most rapidly growing industries, where the equipment and job experience exist and where the future employment opportunities are located.

Such books are easy prey for critics.

Such systems are expensive and are oriented geographically.

Such projections, however, appear highly speculative and the capacities involved are far beyond those foreseen for food-preservation facilities.

Such cases are not considered here.

Such `` depletion allowances '', in the form of percentages of sales are authorized by tax law for specified raw materials producers using up their assets.

Such judgments are meaningful only in so far as persons are members of a world, let us say a community, that embraces Scarsdale or Yonkers, but is also infinitely richer since it is all-inclusive.

And new vistas of hairshirt asceticism are opened by scholarly monographs entitled: `` Friends, Romans, Countrymen, Lend Me Your Ear-Muffs '', `` Such a Phrase as Drifts Through Dream '', and `` The New Vocabularianism ''.

Such explanations do not imply that humans are always consciously calculating how to increase their inclusive fitness when they are doing altruistic acts.